MDCT pp 42-51 | Cite as

Dual-Source CT: Practical Aspects of Techniques and Applications

  • Mannudeep K. Kalra


The quest for non-invasive imaging of cardiac maladies began with conventional radiography and continues to day. Echocardiography has established itself as the screening and diagnostic modality of choice for a variety of cardiac ailments. Since the early 1990s, cardiac magnetic resonance imaging (MRI) has also become an imaging standard of reference for a variety of cardiac pathologies, including cardiac tumors, myocarditis, cardiomyopathies, viability, complex congenital heart diseases, and valvular heart diseases. However, up until the development of multi-detector computed tomography (MDCT) scanners, the imaging of coronary artery diseases with a noninvasive imaging test was a largely elusive approach; instead, invasive conventional coronary catheterization remained and, to date, firmly remains, the imaging modality for most coronary artery diseases.


Dual Energy Compute Tomography Helical Compute Tomography Scanner Distal Coronary Artery Volume Compute Tomography Dose Index Pulse Window 
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  1. 1.
    Kalra MK, Maher MM, D’Souza R, Saini S (2004) Multidetector computed tomography technology: current status and emerging developments. J Comput Assist Tomogr 28(Suppl 1):S2–6CrossRefGoogle Scholar
  2. 2.
    Flohr TG, McCollough CH, Bruder H et al (2006) First performance evaluation of a dual-source CT (DSCT) system. Eur Radiol 2006 16(2):256–68. Epub 2005 Dec 10. Erratum in: Eur Radiol 2006 16(6): 1405CrossRefGoogle Scholar
  3. 3.
    Flohr TG, Schoepf UJ, Ohnesorge BM (2007) Chasing the heart: new developments for cardiac CT. J Thorac Imaging 22(1):4–16CrossRefPubMedGoogle Scholar
  4. 4.
    Marano R, Storto ML, Maddestra N, Bonomo L (2004) Non-invasive assessment of coronary artery bypass graft with retrospectively ECG-gated fourrow multi-detector spiral computed tomography. Eur Radiol 14(8):1353–1362CrossRefPubMedGoogle Scholar
  5. 5.
    Uppot RN, Sahani DV, Hahn PF et al (2006) Effect of obesity on image quality: fifteen-year longitudinal study for evaluation of dictated radiology reports. Radiology 240(2):435–439CrossRefPubMedGoogle Scholar
  6. 6.
    Uppot RN (2007) Impact of obesity on radiology. Radiol Clin North Am (2): 231–246CrossRefGoogle Scholar
  7. 7.
    Sirineni GK, Kalra MK, Pottala K et al (2007) Effect of contrast concentration, tube potential and reconstruction kernels on MDCT evaluation of coronary stents: an in vitro study. Int J Cardiovasc Imaging 23(2):253–263CrossRefPubMedGoogle Scholar
  8. 8.
    Schlosser T, Scheuermann T, Ulzheimer S et al (2007) In vitro evaluation of coronary stents and in-stent stenosis using a dynamic cardiac phantom and a 64-detector row CT scanner. Clin Res Cardiol 96(12):883–890CrossRefPubMedGoogle Scholar
  9. 9.
    Ritman EL, Kinsey JH, Robb RA et al (1980) Physics and technical considerations in the design of the DSR: a high temporal resolution volume scanner. AJR Am J Roentgenol 134:369–374PubMedGoogle Scholar
  10. 10.
    Ritman EL (2003) Cardiac computed tomography imaging: a history and some future possibilities. Cardiol Clin 21:491–513CrossRefPubMedGoogle Scholar
  11. 11.
    McCollough CH, Primak AN, Saba O et al (2007) Dose performance of a 64-channél dual-source CT scanner. Radiology 243(3):775–784CrossRefPubMedGoogle Scholar
  12. 12.
    Kyriakou Y, Kalender WA (2007) Intensity distribution and impact of scatter for dual-source CT. Phys Med Biol 52(23):6969–6989CrossRefPubMedGoogle Scholar
  13. 13.
    Kalra MK, Schmidt B, Suess C et al (2005) Comparison of single and dual source 64-channel MDCT scanners for evaluation of large patients: A phantom study. 91 st Annual Meeting of the Radiological Society of North America, Chicago, IL (Hot topic)Google Scholar
  14. 14.
    Johnson TR, Krauss B, Sedlmair M et al (2007) Material differentiation by dual energy CT: initial experience. Eur Radiol 17(6):1510–1517CrossRefPubMedGoogle Scholar
  15. 15.
    Swensen SJ, Yamashita K, McCollough CH et al (2000) Lung nodules: dual-kilovolt peak analysis with CT—multicenter study. Radiology 214(1):81–85PubMedGoogle Scholar
  16. 16.
    Primak AN, Fletcher JG, Vrtiska TJ et al (2007) Noninvasive differentiation of uric acid versus nonuric acid kidney stones using dual-energy CT. Acad Radiol 4(12):1441–1447CrossRefGoogle Scholar
  17. 17.
    Kalra MK, Blake MA, Sahani DV et al (2007) Dual energy CT for characterization of adrenal adenoma. 93rd Annual Meeting of the Radiological Society of North America (RSNA), Chicago, ILGoogle Scholar
  18. 18.
    Udayasankar U, Li J, Nye J, Small W (2007) Effect of Tube Potential on CT Histogram Analysis of Adrenal Masses. 93rd Annual Meeting of the Radiological Society of North America (RSNA), Chicago, ILGoogle Scholar
  19. 19.
    Deveci S, Coflkun M, Tekin MI et al (2004) Spiral computed tomography: role in determination of chemical compositions of pure and mixed urinary stones—an in vitro study. Urology 64(2):237–240CrossRefPubMedGoogle Scholar
  20. 20.
    Scheffel H, Stolzmann P, Frauenfelder T et al (2007) Dual-energy contrast-enhanced computed tomography for the detection of urinary stone-disease. Invest Radiol 42(12):823–9CrossRefPubMedGoogle Scholar
  21. 21.
    Flohr T, Raupach R, Bruder H (2006) Reduction of the Blooming Effect for Calcified Plaques in CT Angiographic Examinations by Means of dual energy CT. Radiological Society of North America, IL (Scientific paper presented on November, 28, 2006)Google Scholar
  22. 22.
    Scheffel H, Alkadhi H, Plass A et al (2006) Accuracy of dual-source CT coronary angiography: First experience in a high pre-test probability population without heart rate control. Eur Radiol 16(12):2739–2747CrossRefPubMedGoogle Scholar
  23. 23.
    Johnson TR, Nikolaou K, Busch S et al (2007) Diagnostic accuracy of dual-source computed tomography in the diagnosis of coronary artery disease. Invest Radiol 42(10):684–691CrossRefPubMedGoogle Scholar
  24. 24.
    Oncel D, Oncel G, Tastan A (2007) Effectiveness of dual-source CT coronary angiography for the evaluation of coronary artery disease in patients with a trial fibrillation: initial experience. Radiology 245(3):703–711CrossRefPubMedGoogle Scholar
  25. 25.
    Ropers U, Ropers D, Pflederer T et al (2007) Influence of heart rate on the diagnostic accuracy of dual-source computed tomography coronary angiography. J Am Coll Cardiol 50(25):2393–8CrossRefPubMedGoogle Scholar
  26. 26.
    Matt D, Scheffel H, Leschka S et al (2007) Dualsource CT coronary angiography: image quality, mean heart rate, and heart rate variability. AJR Am J Roentgenol 189(3):567–73CrossRefPubMedGoogle Scholar
  27. 27.
    Rist C, Johnson TR, Becker A et al (2007) Dualsource cardiac CT imaging with improved temporal resolution: Impact on image quality and analysis of left ventricular function. Radiologe 47(4):287–290, 292–294CrossRefPubMedGoogle Scholar
  28. 28.
    Busch S, Johnson TR, Wintersperger BJ et al (2007) Quantitative assessment of left ventricular function with dual-source CT in comparison to cardiac magnetic resonance imaging: initial findings. Eur Radiol [Epub ahead of print]Google Scholar
  29. 29.
    Groen JM, Greuter MJ, Vliegenthart R et al (2007) Calcium scoring using 64-slice MDCT, dual source CT and EBT: a comparative phantom study. Int J Cardiovasc Imaging [Epub ahead of print]Google Scholar
  30. 30.
    Pugliese F, Weustink AC, Van Mieghem C et al (2007) Dual-source coronary computed tomography angiography for detecting in-stent restenosis. Heart [Epub ahead of print]Google Scholar
  31. 31.
    Lell MM, Panknin C, Saleh R et al (2007) Evaluation of coronary stents and stenoses at different heart rates with dual source spiral CT (DSCT). Invest Radiol (7):536–541CrossRefGoogle Scholar
  32. 32.
    Mori S, Endo M, Nishizawa K et al (2006) Comparison of patient doses in 256-slice CT and 16-slice CT scanners. Br J Radiol 79(937):56–61CrossRefPubMedGoogle Scholar
  33. 33.
    Funabashi N, Yoshida K, Tadokoro H et al (2005) Cardiovascular circulation and hepatic perfusion of pigs in 4-dimensional films evaluated by 256-slice cone-beam computed tomography. Circ J 69(5):585–589CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Mannudeep K. Kalra
    • 1
  1. 1.Department of RadiologyMassachusetts General HospitalBostonUSA

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