MDCT pp 295-309 | Cite as

MDCT Perfusion in Acute Stroke

  • Sanjay K. Shetty
  • Michael H. Lev


Acute cerebrovascular stroke ranks amongst the foremost causes of morbidity and mortality in the world [1]. In acute settings, the rapid evaluation of acute stroke is invaluable due to the ability to treat patients with thrombolytics. In addition to anatomic information about the acute stroke, state-of-the-art radiologic techniques can also provide critical information about capillary-level hemodynamics and the brain parenchyma. Computed tomography perfusion (CTP) provides this information and can help in understanding the pathophysiology of stroke [2, 3, 4, 5]. CTP helps the physician to identify critically ischemic or irreversibly infarcted tissue (“core”) and to identify severely ischemic but potentially salvageable tissue (“penumbra”). This information can guide triage and management in actue stroke.


Acute Stroke Cerebral Blood Volume Mean Transit Time Compute Tomography Perfusion Ischemic Penumbra 
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Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Sanjay K. Shetty
    • 1
  • Michael H. Lev
    • 2
  1. 1.Department of Radiology Emory University School of MedicineEmory University HospitalAtlantaUSA
  2. 2.Emergency Neuroradiology and Neurovascular LabMassachusetts General HospitalBostonUSA

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