Abstract
For more than 50 years, sternal splitting thymectomy has been the gold standard ever since Blalock first introduced thymectomy for treatment of myasthenia in 1939 [1]. Jaretzki [2] and Masaoka [3] have demonstrated varied distribution of ectopic thymic tissues in the mediastinum and the neck. They both recommend a more extensive resection of tissue beyond the thymic gland itself, using a transcervical-transsternal approach. Minimally invasive thymectomy was introduced by Yim et al. using a right thoracoscopic approach in the early 1990s [4]. Some concern regarding this minimally invasive approach was raised mainly due to questioning the limited exposure, limited working space, and completeness of extended thymectomy which could endanger the therapeutic results [2]. Though controversy surrounds the selection of operation for patients with myasthenia gravis, we developed a novel technique to perform extended thymectomy using video-assisted thoracoscopy by a subxiphoid bilateral approach in early 2001.
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References
Blalock A, Masson MF, Morgan HJ, Riven SS (1939) Myasthenia gravis and tumors of the thymic region: Report of a case in which the tumor was removed. Ann Surg 110:544–561
Jaretzki A III, Wolff MM (1988) “Maximal” thymectomy for myasthenia gravis. J Thorac Cardiovasc Surg 96:711–716
Masaoka A, Nagaoka Y, Kotake Y (1975) Distribution of thymic tissue at the anterior mediastinum — Current procedures in thymectomy. J Thorac Cardiovasc Surg 70:745–754
Yim AP, Kay RLC, Ho JKS (1995) Video-assisted thoracoscopic thymectomy for myasthenia gravis. Chest 108:1440–1443
Hsu CP (2002) Subxiphoid approach for thoracoscopic thymectomy. Surg Endosc 16:1105
Hsu CP, Chuang CY, Hsu NY, Shia SE (2002) Subxiphoid approach for video-assisted thoracoscopic extended thymectomy in treating myasthenia gravis. Interactive Cardiovasc Thorac Surgery 1:4–8
Hsu CP, Chuang CY, Hsu NY, Chen CY (2004) Comparison between the right side and subxiphoid bilateral approaches in performing video-assisted thoracoscopic extended thymectomy for myasthenia gravis. Surg Endosc 18:821–824
Mack MJ, Landreneau RJ, Yim AP et al (1996) Results of VATS thymectomy in patients with myasthenia gravis. J Thorac Cardiovasc Surg 112:1352–1360
Savcenko M, Wendt GK, Prince SL, Mack M (2002) Video-assisted thymectomy for myasthenia gravis: An update of a single institution experience. Eur J Cardio Thorac Surg 22:978–983
Rückert JC, Sobel HK, Göhring S et al (2003) Matchedpair comparison of three different approaches for thymectomy in myasthenia gravis. Surg Endosc 17:711–715
Ashour M (1995) Prevalence of ectopic thymic tissue in myasthenia gravis and its clinical significance. J Thorac Cardiovasc Surg 109:632–635
Fukai I, Funato Y, Mizumo T et al (1991) Distribution of thymic tissue in the mediastinal adipose tissue. J Thorac Cardiovasc Surg 101:1099–1102
Özdemira N, Karab M, Dikmenb E et al (2003) Predictors of clinical outcome following extended thymectomy in myasthenia gravis Euro J Cardio Thorac Surg 23:233–237
Kido T, Hazama K, Inoue Y et al (1999) Resection of anterior mediastinal masses through an infrasternal approach. Ann Thorac Surg 67:263–265
Takeo S, Sakada T, Yano T (2001) Video-assisted extended thymectomy in patients with thymoma by lifting the sternum. Ann Thorac Surg 71:1721–1723
Uchiyama A, Shimizu S, Murai H et al (2001) Infrasternal mediastinoscopic thymectomy in myasthenia gravis: Surgical results in 23 patients. Ann Thorac Surg 72:1902–1905
Uchiyama A, Shimizu S, Murai H et al (2004) Infrasternal mediastinoscopic surgery for anterior mediastinal masses. Surg Endosc 18:843–846
Wright GM, Barnett S, Clarke CP (2002). Video-assisted thoracoscopic thymectomy for myasthenia gravis. Int Med J 32:367–371
Wolfe GI, Gross B (2004) Treatment review and update for myasthenia gravis. J Clinic Neuromuscular Dis 6:54–68
Manlulu A, Lee TW, Wan I et al (2005) Video-assisted thoracic surgery thymectomy for nonthymomatous myasthenia gravis. Chest 128:3454–3460
Jaretzki A III, Aarli JA, Kaminski HJ et al (2003) Thymectomy for myasthenia gravis: Evaluation requires controlled prospective studies. Ann Thorac Surg 76:1–3
Mantegazza R, Baggi F, Bernasconi P et al (2003) Video-assisted thoracoscopic extended thymectomy and extended thymectomy (T-3b) in non-thymomatous myasthenia gravis patients: Remission after 6 years of follow-up. J Neurol Sci 212:31–36
Jaretzki A III (2003) Thymectomy for myasthenia gravis: Analysis of controversies — Patient management. Neurologist 9:77–92
Huang CS, Hsu HS, Huang BS et al (2005) Factors influencing the outcome of transsternal thymectomy for myasthenia gravis. Acta Neurol Scand 112:108–114
Chang PC, Chou SH, Kao EL et al (2005) Bilateral video-assisted thoracoscopic thymectomy vs. extended transsternal thymectomy in myasthenia gravis: A prospective study. Eur Surg Res 37:199–203
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Hsu, CP., Chuang, CY. (2008). Open Videoassisted Techniques: Subxiphoid Approach with Bilateral Thoracoscopy. In: Lavini, C., Moran, C.A., Morandi, U., Schoenhuber, R. (eds) Thymus Gland Pathology. Springer, Milano. https://doi.org/10.1007/978-88-470-0828-1_18
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DOI: https://doi.org/10.1007/978-88-470-0828-1_18
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