Anesthesiological Problems in Thymus Gland Surgery

  • Vincenzo Lucio Indrizzi
  • Fabio Gazzotti
  • Maria Antonietta Fanigliulo
  • Alberto Tassi


In Italy, about 15,000 patients are known to suffer from myasthenia gravis; however, in other cases the condition is not diagnosed or is confused with other pathologies. In Europe, it is thought that about 6 in 100,000 inhabitants are affected, and in the USA the incidence has been estimated at 20 cases for every 100,000 inhabitants. As regards the patient’s age at onset, there are two peaks: between 20 and 40 years of age (women most affected) and 60 to 80 years (no difference between the sexes). This data would suggest that myasthenia gravis patients rarely undergo surgery; on the contrary, as thymectomy causes a significant improvement in symptoms in 40–90% of cases and complete remission of the disease in 25% of cases, surgery in patients with myasthenia gravis (especially in large centers with a Chest Surgery Unit) is not uncommon [1].


Orotracheal Intubation Plasma Cholinesterase Early Extubation Myasthenic Patient Nondepolarizing Muscle Relaxant 
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Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Vincenzo Lucio Indrizzi
    • 1
  • Fabio Gazzotti
    • 1
  • Maria Antonietta Fanigliulo
    • 1
  • Alberto Tassi
    • 1
  1. 1.2nd Anesthesia and Resuscitation ServiceUniversity of Modena and Reggio Emilia General HospitalModenaItaly

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