Estratto
L’impiego di sostanze chimiche per prevenire o ritardare l’alterazione degli alimenti deriva in parte dal fatto che tali composti sono utilizzati con grande successo nel trattamento di patologie dell’uomo, degli animali e delle piante. Ciò non implica che qualsivoglia composto chemioterapico possa o debba essere impiegato come conservante per alimenti. D’altra parte vi sono alcuni composti chimici utili come conservanti che potrebbero essere inefficaci o addirittura tossici come chemioterapici. A eccezione di alcuni antibiotici, nessuno dei conservanti per alimenti oggi utilizzati trova un impiego reale per la cura dell’uomo e degli animali. Sebbene molteplici sostanze chimiche abbiano un certo potenziale come conservanti alimentari, solo un numero relativamente piccolo è consentito nei prodotti alimentari, ciò è dovuto in gran parte alle stringenti norme di sicurezza stabilite dalla FDA e in misura minore al fatto che non tutti i composti che mostrano attività antimicrobica in vitro esplicano la stessa azione negli alimenti. Di seguito sono descritti i composti maggiormente utilizzati, le loro modalità di azione — se conosciute — e le tipologie di alimenti in cui vengono impiegati. I conservanti chimici generalmente riconosciuti sicuri (GRAS, generally recognized as safe) sono riassunti nella tabella 13.1.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Bibliografia
Abee T (1995) Pore-forming bacteriocins of Gram-positive bacteria and self-protection mechanisms of producer organisms. FEMS Microbiol Lett, 129: 1–10.
Achen M, Yousef AE (2001) Efficacy of ozone against Escherichia coli O157:H7 on apples. J Food Sci, 66: 1380–1384.
Alakomi HL, Skytta E, Saarela M, Mattila-Sandholm T, Latva-Kala K, Helander IM (2000) Lactic acid permeabilizes Gram-negative bacteria by disrupting the outer membrane. Appl Environ Microbiol, 66: 2001–2005.
Amézquita A, Brashears MM (2002) Competitive inhibition of Listeria monocytogenes in ready-toeat meat products by lactic acid bacteria. J Food Protect, 65: 316–325.
Anderson GL, Caldwell KC, Beuchat LR, Williams PL (2003) Interaction of a free-living soil nematode, Caenorhabditis elgans, with surrogates of foodborne pathogenic bacteria. J Food Protect, 66: 1543–1549.
Atterbury RJ, Connerton PL, Dodd CER, Rees CED, Connerton IF (2003) Application of host-specific bacteriophages to the surface of chicken skin leads to a reduction in recovery of Campylobacter jejuni. Appl Environ Microbiol, 69: 6302–6306.
Atterbury RJ, Connerton PL, Dodd CER, Rees CED, Connerton IF (2003) Isolation and characterization of Campylobacter bacteriophages from retail poultry. Appl Environ Microbiol, 69: 4511–4518.
Aymerich MT, Hugas M, Monfort JM (1998) Review: Bacteriocinogenic lactic acid bacteria associated with meat products. Food Sci Technol Int, 4: 141–158.
Banks JG, Board RG (1982) Sulfite inhibition of Enterobacteriacae including Salmonella in British fresh sausage and in culture systems. J Food Protect, 45: 1292–1297, 1301.
Bari ML, Sabina Y, Isobe S, Uemura T, Isshiki K (2003) Effectiveness of electrolyzed acidic water in killing Escherichia coli O157:H7, Salmonella Enteritidis, and Listeria monocytogenes on the surfaces of tomatoes. J Food Protect, 66: 542–548.
Bari ML, Inatsu Y, Kawasaki S et al. (2002) Calcinated calcium killing of Escherichia coli 0157:H7, Salmonella, and Listeria monocytogenes on the surface of tomatoes. J Food Protect, 65: 1706–1711.
Barker C, Park SF (2001) Sensitization of Listeria monocytogenes to low pH, organic acids, and osmotic stress by ethanol. Appl Environ Microbiol, 67: 1594–1600.
Bedie GK, Samelis J, Sofos JN, Belk KE, Scanga JA, Smith GC (2001) Antimicrobials in the formulation to control Listeria monocytogenes postprocessing contamination on frankfurters stored at 4 °C in vacuum packages. J Food Protect, 64: 1949–1955.
Berry BW, Blumer TN (1981) Sensory, physical, and cooking characteristics of bacon processed with varying levels of sodium nitrite and potassium sorbate. J Food Sci, 46: 321–327.
Beuchat LR, Ward TE, Pettigrew CA (2001) Comparison of chlorine and a prototype produce wash product for effectiveness in killing Salmonella and Escherichia coli O157:H7 on alfalfa seeds. J Food Protect, 64: 152–158.
Blake DF, Stumbo CR (1970) Ethylene oxide resistance of microorganisms important in spoilage of acid and high-acid foods. J Food Sci, 35: 26–29.
Bosund I (1962) The action of benzoic and salicylic acids on the metabolism of microorganisms. Adv Food Res, 11: 331–353.
Bowen VG, Deibel RH (1974) Effects of nitrite and ascorbate on botulinal toxin formation in wieners and bacon. In: Proceedings of the Meat Industry Research Conference. American Meat Institute Foundation, Chicago, pp. 63-68.
Branen AL, Davidson PM, Katz B (1980) Antimicrobial properties of phenolic, antioxidants and lipids. Food Technol, 34(5): 42–53, 63.
Bredholt S, Nasbakken T, Holck A (1999) Protective cultures inhibit growth of Listeria monocytogenes and Escherichia coli O157:H7 in cooked, sliced, vacuum-and gas-packaged meat. Int J Food Microbiol, 53: 43–52.
Breukink E, Wiedemann I, van Kraaij C, Kulpers OP, Sahl HG, de Kruijff B (1999) Use of the cellwall precursor lipid II by a pore-forming peptide antibiotic. Science, 286: 2361–2364.
Budu-Amoako E, Ablett RF, Harris J, Delves-Broughton J (1999) Combined effect of nisin and moderate heat on destruction of Listeria monocytogenes in cold-pack lobster meat. J Food Protect, 62: 46–50.
Bullerman LB, Lieu FY, Seier SA (1977) Inhibition of growth and aflatoxin production by cinnamon and clove oils, cinnamic aldehyde and eugenol. J Food Sci, 42: 1107–1109, 1116.
Buyong N, Kok J, Luchansky JB (1998) Use of a genetically enhanced, pedio-producing starter culture, Lactococcus lactis subsp. lactis MM217, to control Listeria monocytogenes in Cheddar cheese. Appl Environ Microbiol, 64: 4842–4845.
Byun M-W, Kwon O-J, Yook H-S, Kim K-S (1998) Gamma Irradiation and Ozone Treatment for Inactivation of Escherichia coli O157:H7 in Culture Media. J Food Protect, 61:728–730.
Caldwell KN, Adler BB, Anderson GL, Williams PI, Beuchat LR (2003) Ingestion of Salmonella enterica serotype Poona by a free-living nematode, Caenorhabditis elegans, and protection against inactivation by produce sanitizers. Appl Environ Microbiol, 69: 4103–4110.
Callaway TR, Carneiro de Melo AMS, Russell JB (1997) The effect of nisin and monensin on ruminal fermentations in vitro. Curr Microbiol, 35: 90–96.
Capita R, Alonso-Calleja C, Prieto M, del Camino Garcia-Fernández M, Moreno B (2003) Effectiveness of trisodium phosphate against Listeria monocytogenes on excised and nonexcised chicken skin. J Food Protect, 66: 61–64.
Carnio MC, Höltzel A, Rudolf M, Henle T, Jung G, Scherer S (2000) The macrocyclic peptide antibiotic micrococcin P1 is secreted by the food-borne bacterium Staphylococcus equorum WS2733 and inhibits Listeria monocytogenes on soft cheese. Appl Environ Microbiol, 66: 2378–2384.
Cassens RG (1995) Use of sodium nitrite in cured meats today. Food Technol, 49(7): 72–80, 115.
Castillo A, McKenzie KS, Lucia LM, Acuff GR (2003) Ozone treatment for reduction of Escherichia coli O157:H7 and Salmonella serotype Typhimurium on beef carcass surfaces. J Food Protect, 66: 775–779.
Cerrutti P, Terebiznik MR, de Huergo MS, Jagus R, Pilosof AMR (2001) Combined effect of water activity and pH on the inhibition of Escherichia coli by nisin. J Food Protect, 64: 1510–1514.
Chang PC, Akhtar SM, Burke T, Pivnick H (1974) Effect of sodium nitrite on Clostridium botulinum in canned luncheon meat: Evidence for a Perigo-type factor in the absence of nitrite. Can Inst Food Sci Technol J, 7: 209–212.
Cheng MKC, Levin RE (1970) Chemical destruction of Aspergillus niger conidiospores. J Food Sci, 35: 62–66.
Christiansen LN, Johnston RW, Kautter DA, Howard JW, Aunan WJ (1973) Effect of nitrite and nitrate on toxin production by Clostridium botulinum and on nitrosamine formation in perishable canned comminuted cured meat. Appl Microbiol, 25: 357–362.
Christiansen LN, Tompkin RB, Shaparis AB, Kueper TV, Johnston RW, Kautter DA, Kolari OJ (1974) Effect of sodium nitrite on toxin production by Clostridium botulinum in bacon. Appl Microbiol, 27: 733–737.
Collins-Thompson DL, Sen NP, Aris B, Schwinghamer L (1972) Nonenzymic in vitro formation of nitrosamines by bacteria isolated from meat products. Can J Microbiol, 18: 1968–1971.
Dack GM, Lippitz G (1962) Fate of staphylococci and enteric microorganisms introduced into slurry of frozen pot pies. Appl Microbiol, 10: 472–479.
Davidson PM (1983) Phenolic compounds. In: Branen AL, Davidson PM (eds) Antimicrobials in Foods. Marcel Dekker, New York. pp. 37–73.
Davidson PM, Brekke CJ, Branen AL (1981) Antimicrobial activity of butylated hydroxyanisole, tertiary butylhydroquinone, and potassium sorbate in combination. J Food Sci, 46: 314–316.
Delves-Broughton J (1990) Nisin and its uses as a food preservative. Food Technol, 44(11): 100, 102, 104, 106, 108, 111–112, 117.
Denny CB, Sharpe LE, Bohrer CW (1961) Effects of tylosin and nisin on canned food spoilage bacteria. Appl Microbiol, 9: 108–110.
DePaola A, Motes ML, Chan AM, Suttle CA (1998) Phages infecting Vibrio vulnificus are abundant and diverse in oysters (Crassostrea virginica) collected from the Gulf of Mexico. Appl Environ Microbiol, 64: 346–351.
Dethmers AE, Rock H, Fazio T, Johnston RW (1975) Effect of added sodium nitrite and sodium nitrate on sensory quality and nitrosamine formation in Thuringer sausage. J Food Sci, 40: 491–495.
Deuel HJ Jr, Calbert CE, Anisfeld L, McKeechan H, Blunden HD (1954) Sorbic acid as a fungistatic agent for foods. II. Metabolism of α,β-unsaturated fatty acids with emphasis on sorbic acid. Food Res, 19: 13–19.
Deutsch SM, Guezenec S, Piot M, Foster S, Lortal S (2004) Mur-LH, the broad-spectrum endolysin of Lactobacillus helveticus temperate-bacteriophage (Φt0303). Appl Environ Microbiol, 70: 96–103.
Dimick KP, Alderton G, Lewis JC, Lightbody HD, Fevold HL (1947) Purification and properties of subtilin. Arch Biochem, 15: 1–11.
Doores S (1983) Organic acids. In: Branen AL, Davidson PM (eds) Antimicrobials in Foods. Marcel Dekker, New York, pp. 75–107.
Doyle MP, Marth EH (1978) Bisulfite degrades aflatoxins. Effect of temperature and concentration of bisulfite. J Food Protect, 41: 774–780.
Duncan CL, Foster EM (1968) Role of curing agents in the preservation of shelf-stable canned meat products. Appl Microbiol, 16: 401–405.
Dymicky M, Trenchard H (1982) Inhibition of Clostridium botulinum 62A by saturated n-aliphatic acids, n-alkyl formates, acetates, propionates and butyrates. J Food Protect, 45: 1117–1119.
Eckert JW (1979) Fungicidal and fungistatic agents: Control of pathogenic microorganisms on fresh fruits and vegetables after harvest. In: Rhodes ME (ed) Food Mycology. Hall, Boston, pp. 164–199.
Eklund T (1985) The effect of sorbic acid and esters of p-hydroxybenzoic acid on the protonmotive force in Escherichia coli membrane vesicles. J Gen Microbiol, 131: 73–76.
El-Ziney MG, van den Tempel MGT, Debevere J (1999) Application of reuterin produced by Lactobacillus reuteri 12002 for meat decontamination and preservation. J Food Protect, 62: 257–261.
Entani E, Asai M, Tsujihata S, Tsukamoto Y, Ohta M (1998) Antibacterial action of vinegar against food-borne pathogenic bacteria including Escherichia coli O157:H7. J Food Protect, 61: 953–959.
Fabrizio KA, Cutter CN (2003) Stability of electrolyzed oxidizing water and its efficacy against cell suspensions of Salmonella Typhimurium and Listeria monocytogenes. J Food Protect, 66: 1379–1384.
Fisher TL, Golden DA (1998) Survival of Escherichia coli O157:H7 in apple cider as affected by dimethyl dicarbonate, sodium bisulfite, and sodium benzoate. J Food Sci, 63: 904–906.
Florey HW (1946) The use of micro-organisms for therapeutic purposes. Yale J Biol Med, 19: 101–118.
Fong YY, Chan WC (1973) Bacterial production of di-methyl nitrosamine in salted fish. Nature, 243: 421–422.
Food and Agriculture Organization/World Health Organization (FAO/WHO) (1976) Evaluation of Certain Food Additives. WHO Technical Report Series 599.
Francis GA, Thomas C, O’Beirne D (1999) Review paper: The microbiological safety of minimally processed vegetables. Int J Food Sci Technol, 34: 1–22.
Frank JF, Ehlers J, Wicker L (2003) Removal of Listeria monocytogenes and poultry soil-containing biofilms using chemical cleaning and sanitizing agents under static conditions. Food Protect Trends, 23: 654–663.
Freese E, Sheu CW, Galliers E (1973) Function of lipophilic acids as antimicrobial food additives. Nature, 241: 321–325.
Fung DYC, Lin CCS, Gailani MB (1985) Effect of phenolic antioxidants on microbial growth. CRC Crit Rev Microbiol, 12: 153–183.
Gaeng S, Scherer S, Neve H, Loessner MJ (2002) Gene cloning and expression and secretion of Listeria monocytogenes bacteriophage-lytic enzymes in Lactococcus lactis. Appl Environ Microbiol, 66: 2951–2958.
Gailani MB, Fung DYC (1984) Antimicrobial effects of selected antioxidants in laboratory media and in ground pork. J Food Protect, 47: 428–433.
Garcia A, Mount JR, Davidson PM (2003) Ozone and chlorine treatment of minimally processed lettuce. J Food Sci, 68: 2747–2751.
Gill AO, Holley RA (2000) Surface application of lysozyme, nisin, and EDTA to inhibit spoilage and pathogenic bacteria on ham and bologna. J Food Protect, 63: 1338–1346.
Glass KA, Granberg DA, Smith AL, McNamara AM, Hardin M, Mattias J, Ladwig K, Johnson EA (2002) Inhibition of Listeria monocytogenes by sodium diacetate and sodium lactate on wieners and cooked bratwurst. J Food Protect, 65: 116–123.
Goepfert JM, Kim HU (1975) Behavior of selected foodborne pathogens in raw ground beef. J Milk Food Technol, 35: 449–452.
Goode D, Allen VM, Barrow PA (2003) Reduction of experimental Salmonella and Campylobacter contamination of chicken skin by application of lytic bacteriophages. Appl Environ Microbiol, 69: 5032–5036.
Goodridge L, Gallaccio A, Griffiths MW (2003) Morphological, host range, and genetic characterization of two coliphages. Appl Environ Microbiol, 69: 5364–5371.
Gould GW (1964) Effect of food preservatives on the growth of bacteria from spores. In: Molin G (ed) Microbial Inhibitors in Foods. Almquist & Wiksell, Stockholm, pp. 17–24.
Gould GW, Brown MH, Fletcher BC (1983) Mechanisms of action of food preservation procedures. In: Roberts TA, Skinner FA (eds) Food Microbiology: Advances and Prospects. Academic Press, New York, pp. 67–84.
Gray JI, Pearson AM (1984) Cured meat flavor. Adv Food Res, 29: 1–86.
Greer GG (1986) Homologous bacteriophage control of Pseudomonas growth and beef spoilage. J Food Protect, 49: 104–109.
Hagler WM Jr, Hutchins JE, Hamilton PB (1982) Destruction of aflatoxin in corn with sodium bisulfite. J Food Protect, 45: 1287–1291.
Hamilton-Miller JMT (1974) Fungal sterols and the mode of action of the polyene antibiotics. Adv Appl Microbiol, 17: 109–134.
Harp E, Gilliland SE (2003) Evaluation of a select strain of Lactobacillus delbrueckii subsp. lactis as a biological control agent for pathogens on fresh-cut vegetables stored at 7 °C. J Food Protect, 66: 1013–1018.
Hawksworth G, Hill MJ (1971) The formation of nitrosamines by human intestinal bacteria. Biochem J, 122: 28–29P.
Hawksworth G, Hill MJ (1971) Bacteria and the N-nitrosation of secondary amines. Brit J Cancer, 25: 520–526.
Hechelman H, Leistner L (1969) Hemmung von unerwunschtem Schimmelpilzwachstum auf Rohwursten durch Delvocid (Pimaricin). Fleischwirtschaft, 49: 1639–1641.
Herranz C, Chen V, Chung HJ, Cintas LM, Hernández PE, Montville TJ, Chikindas ML (2001) Enterocin P selectively dissipates the membrane potential of Enterococcus faecium T136. Appl Environ Microbiol, 67: 1689–1692.
Holzapfel WH, Geisen R, Schillinger U (1995) Biological preservation of foods with reference to protective cultures, bacteriocins and food-grade enzymes. Int J Food Microbiol, 24: 343–362.
Holley RA (1981) Prevention of surface mold growth on Italian dry sausage by natamycin and potassium sorbate. Appl Environ Microbiol, 41: 422–429.
Holyoak CD, Stratford M, McMullin A, Cole MB, Crimmins K, Brown AJP, Coote PJ (1996) Activity of the plasma membrane H-ATPase and optimal glycolytic flux are required for rapid adaptation and growth of Saccharomyces cerevisiae in the presence of the weak-acid preservative sorbic acid. Appl Environ Microbiol, 62: 3158–3164.
Hoover DG, Steenson LR (eds) (1993) Bacteriocins of Lactic Acid Bacteria. Academic Press, New York.
Huhtanen CN (1980) Inhibition of Clostridium botulinum by spice extracts and aliphatic alcohols. J Food Protect, 43: 195–196, 200.
Hurst A (1981) Nisin. Adv Appl Microbiol, 27: 85–123.
Islam M, Chen J, Doyle MP, Chinnan M (2002) Control of Listeria monocytogenes on turkey frankfurters by generally-recognized-as-safe preservatives. J Food Protect, 65: 1411–1416.
Ivey FJ, Shaver KJ, Christiansen LN, Tompkin RB (1978) Effect of potassium sorbate on toxinogenesis by Clostridium botulinum in bacon. J Food Protect, 41: 621–625.
Jack RW, Tagg JR, Ray B (1995) Bacteriocins of Gram-positive bacteria. Microbiol Rev, 59: 171–200.
Jacobsen T, Budde BB, Koch AG (2003) Application of Leuconostoc carnosum for biopreservation of cooked meat products. J Appl Microbiol, 95: 242–249.
Jay JM (1997) Do background microorganisms play a role in the safety of fresh foods? Trends Food Sci Technol, 8: 421–424.
Jay JM (1982) Antimicrobial properties of diacetyl. Appl Environ Microbiol, 44: 525–532.
Jay JM (1982) Effect of diacetyl on foodborne microorganisms. J Food Sci, 47: 1829–1831.
Jay JM (1983) Antibiotics as food preservatives. In: Rose AH (ed) Food Microbiology. Academic Press, New York, pp. 117–143.
Jay JM, Rivers GM (1984) Antimicrobial activity of some food flavoring compounds. J Food Safety, 6: 129–139.
Juglal S, Govinden R, Odhav B (2002) Spice oils for the control of co-occurring mycotoxin-producing fungi. J Food Protect, 65: 683–687.
Kabara JJ (1983) Medium-chain fatty acids and esters. In: Branen AL, Davidson PM (eds) Antimicrobials in Foods. Marcel Dekker, New York, pp. 109–139.
Kabara JJ, Vrable H, Lie Ken Jie MSF (1977) Antimicrobial lipids: Natural and synthetic fatty acids and monoglycerides. Lipids, 12: 753–759.
Kang DH, Fung DYC (2000) Stimulation of starter culture for further reduction of foodborne pathogens during salami fermentation. J Food Protect, 63: 1492–1495.
Katla T, Naterstad K, Vancanneyt M, Swings J, Axelsson L (2003) Differences in susceptibility of Listeria monocytogenes strains to sakacin P, sakacin A, pediocin PA-1, and nisin. Appl Environ Microbiol, 69: 4431–4437.
Kemp GK, Aldrich ML, Waldroup AL (2000) Acidified sodium chlorite antimicrobial treatment of broiler carcasses. J Food Protect, 63: 1087–1092.
Kennedy JE Jr, Oblinger JL, Bitton B (1984) Recovery of coliphages from chicken, pork sausage and delicatessen meats. J Food Protect, 47: 623–626.
Kereluk K, Gammon HA, Lloyd RS (1970) Microbiological aspects of ethylene oxide sterilization. II. Microbial resistance to ethylene oxide. Appl Microbiol, 19: 152–156.
Kim KW, Thomas RL, Lee C, Park HJ (2003) Antimicrobial activity of native chitosan, degraded chitosan, and o-carboxymethylated chitosan. J Food Protect, 66: 1495–1498.
Kim JG, Yousef AE (2000) Inactivation kinetics of foodborne spoilage and pathogenic bacteria by ozone. J Food Sci, 65: 521–528.
Kim JG, Yousef AE, Dave SA (1999) Application of ozone for enhancing the microbiological safety and quality of foods: A review. J Food Protect, 62: 1071–1087.
Klis JB, Witter LD, Ordal ZJ (1964) The effect of several antifungal antibiotics on the growth of common food spoilage fungi. Food Technol, 13: 124–128.
Kniel KE, Sumner SS, Lindsay DS, Hackney CR, Pierson MD, Zajac AM, Golden DA, Fayer D (2003) Effect of organic acids and hydrogen peroxide on Cryptosporidium parvum viability in fruit juices. J Food Protect, 66: 1650–1657.
Kueper TV, Trelease RD (1974) Variables affecting botulinum toxin development and nitrosamine formation in fermented sausages. In: Proceedings of the Meat Industry Research Conference. American Meat Institute Foundation, Chicago, pp. 69–74.
Labbe RG, Kinsley M, Wu J (2001) Limitations in the use of ozone to disinfect maple sap. J Food Protect, 64: 104–107.
Lana RP, Russell JB (1997) Effect of forage quality and monensin on the ruminal fermentation of fistulated cows fed continuously at a constant intake. J Anim Sci, 75: 224–229.
Leistner L, Gould G (2002) Hurdle Technologies — Combination Treatments for Food Stability, Safety and Quality. Kluwer Academic Publishers, New York.
LeMarrec C, Hyronimus B, Bressollier P, Verneuil B, Urdaci MC (2000) Biochemical and genetic characterization of coagulin, a new antilisterial bacteriocin in the pediocin family of bacteriocins, produced by Bacillus coagulans I4. Appl Environ Microbiol, 66: 5213–5220.
Lin CCS, Fung DYC (1983) Effect of BHA, BHT, TBHQ, and PG on growth and toxigenesis of selected aspergilli. J Food Sci, 48: 576–580.
Lin CM, Moon SS, Doyle MP, McWatters KH (2002) Inactivation of Escherichia coli O157:H7, Salmonella enterica serotype Enteritidis, and Listeria monocytogenes on lettuce by hydrogen peroxide and lactic acid and by hydrogen peroxide with mild heat. J Food Protect, 65: 1215–1220.
Lin CM, Kim J, Du WX, Wei CI (2000) Bactericidal activity of isothiocyanate against pathogens on fresh produce. J Food Protect, 63: 25–30.
Lloyd AC (1975) Preservation of comminuted orange products. J Food Technol, 10: 565–567.
Loessner MJ, Maier SK, Schiwek P, Scherer S (1997) Long-chain polyphosphates inhibit growth of Clostridium tyrobutyricum in processed cheese spreads. J Food Protect, 60: 493–498.
Maier SK, Scherer S, Loessner MJ (1999) Long-chain polyphosphate causes cell lysis and inhibits Bacillus cereus septum formation, which is dependent on divalent cations. Appl Environ Microbiol, 65: 3942–3949.
McCann KB, Lee A, Wan J, Roginski H, Coventry MJ (2003) The effect of bovine lactoferrin and lactoferricin B on the ability of feline calicivirus (a norovirus surrogate) and poliovirus to infect cell cultures. J Appl Microbiol, 95: 1026–1033.
McDonnell G, Grignol G, Ankloga K (2002) Vapor phase hydrogen peroxide decontamination of food contact surfaces. Dairy Food Environ Sanit, 22: 868–873.
McEntire JC, Montville TJ, Chikindas ML (2003) Synergy between nisin and select lactates against Listeria monocytogenes is due to the metal cations. J Food Protect, 66: 1631–1636.
McMeekin TA, Presser K, Ratkowsky D et al. (2000) Quantifying the hurdle concept by modeling the bacterial growth/no growth interface. Int J Food Microbiol, 55: 93–98.
Melly E, Cowan AE, Setlow P (2002) Studies on the mechanism of killing of Bacillus subtilis spores by hydrogen peroxide. J Appl Microbiol, 93: 316–325.
Meyer JD, Cerveny JG, Luchansky JB (2003) Inhibition of nonproteolytic, psychrotrophic clostridia and anaerobic sporeformers by sodium diacetate and sodium lactate in cook-in-bag turkey breast. J Food Protect, 66: 1474–1478.
Miller SA, Brown WD (1984) Effectiveness of chlortetracycline in combination with potassium sorbate or tetrasodium ethylene-diaminetetraacetate for preservation of vacuum packed rockfish fillets. J Food Sci, 49: 188–191.
Miller ML, Martin ED (1990) Fate of Salmonella Enteritidis and Salmonella Typhimurium into an Italian salad dressing with added eggs. Dairy Food Environ Sanit, 10(1): 12–14.
Ming X, Daeschel MA (1995) Correlation of cellular phospholipid content with nisin resistance of Listeria monocytogenes Scott A. J Food Protect, 58: 416–420.
Morita H, Sakata R, Nagata Y (1998) Nitric oxide complex of iron (II) myoglobin converted from metmyoglobin by Staphylococcus xylosus. J Food Sci, 63: 352–355.
Morris JA, Khettry A, Seitz EW (1979) Antimicrobial activity of aroma chemicals and essential oils. J Am Oil Chem Soc, 56: 595–603.
Muthukumarasamy PJ, Han H, Holley RA (2003) Bactericidal effects of Lactobacillus reuteri and allyl isohiocyanate on Escherichia coli O157:H7 in refrigerated ground beef. J Food Protect, 66: 2038–2044.
Naidu AS (2002) Activated lactoferrin-A new approach to meat safety. Food Technol, 56(3): 40–45.
Naidu AS (2000) Microbial blocking agents: Anew approach to meat safety. Food Technol, 54(2): 112.
Nascimento HS, Silva N, Catanozi MPLM, Silva KC (2003) Effects of different disinfection treatments on the natural microbiota of lettuce. J Food Protect, 66: 1697–1700.
Nilsson L, Chen V, Chikindas ML, Huss HH, Gram L, Montville TJ (2000) Carbon dioxide and nisin act synergistically on Listeria monocytogenes. Appl Microbiol Environ, 66: 769–774.
Nilsson L, Gram L, Huss HH (1999) Growth control of Listeria monocytogenes on cold-smoked salmon using a competitive lactic acid bacteria flora. J Food Protect, 62: 336–342.
Niroomand F, Sperber WH, Lewandowski VJ, Hobbs LJ (1998) Fate of bacterial pathogens and indicator organisms in liquid sweeteners. J Food Protect, 61: 295–299.
No HK, Park NY, Lee SH, Hwang HJ, Meyers SP (2002) Antibacterial activities of chitosans and chitosan oligomers with different molecular weights on spoilage bacteria isolated from tofu. J Food Sci, 67: 1511–1514.
Nordin HR (1969) The depletion of added sodium nitrite in ham. Can Inst Food Sci Technol J, 2: 79–85.
O’Boyle AR, Rubin LJ, Diosady LL, Aladin-Kassam N, Comer F, Brightwell W (1990) A nitritefree curing system and its application to the production of wieners. Food Technol, 44(5): 88, 90–91, 93, 95–96, 98, 100, 102–104.
O’Leary V, Solberg M (1976) Effect of sodium nitrite inhibition on intracellular thiol groups and on the activity of certain glycolytic enzymes in Clostridium perfringens. Appl Environ Microbiol, 31: 208–212.
Ough CS (1983) Sulfur dioxide and sulfites. In: Branen AL, Davidson PM (eds) Antimicrobials in Foods. Marcel Dekker, New York, pp. 177–203.
Paquette MW, Robach MC, Sofos JN, Busta F (1980) Effects of various concentrations of sodium nitrite and potassium sorbate on color and sensory qualities of commercially prepared bacon. J Food Sci, 45: 1293–1296.
Park CM, Beuchat LR (1999) Evaluation of sanitizers for killing Escherichia coli O157:H7, Salmonella, and naturally occurring microorganisms on cantaloupes, honeydewmelons, and asparagus. Dairy Food Environ Sanit, 19: 842–847.
Perigo JA, Roberts TA (1968) Inhibition of clostridia by nitrite. J Food Technol, 3: 91–94.
Perigo JA, Whiting E, Bashford TE (1967) Observations on the inhibition of vegetative cells of Clostridium sporogenes by nitrite which has been autoclaved in a laboratory medium, discussed in the context of sublethally processed meats. J Food Technol, 2: 377–397.
Peterson AC, Black JJ, Gunderson MF (1962) Staphylococci in competition. I. Growth of naturally occurring mixed populations in precooked frozen foods during defrost. Appl Microbiol, 10: 16–22.
Pierson MD, Reddy NR (1982) Inhibition of Clostridium botulinum by antioxidants and related phenolic compounds in comminuted pork. J Food Sci, 47: 1926–1929, 1935.
Pitt WM, Harden TJ, Hull RR (2000) Behavior of Listeria monocytogenes in pasteurized milk during fermentation with lactic acid bacteria. J Food Protect, 63: 916–920.
Porto ACS, Franco BDGM, Sant’Anna ES, Call JK, Piva A, Luchansky JB (2002) Viability of a five-strain mixture of Listeria monocytogenes in vacuum-sealed packages of frankfurters, commercially prepared with and without 2.0 or 3.0% added potassium lactate, during extended storage at 4 and 10 °C. J Food Protect, 65: 308–315.
Raccach M, Baker RC (1978) Lactic acid bacteria as an antispoilage and safety factor in cooked, mechanically deboned poultry meat. J Food Protect, 41: 703–705.
Rayman K, Malik N, Hurst A (1983) Failure of nisin to inhibit outgrowth of Clostridium botulinum in a model cured meat system. Appl Environ Microbiol, 46: 1450–1452.
Reddy D, Lancaster JR Jr, Cornforth DP (1983) Nitrite inhibition of Clostridium botulinum: Electron spin resonance detection of iron-nitric oxide complexes. Science, 221: 769–770.
Robach MC, Pierson MD (1979) Inhibition of Clostridium botulinum types A and B by phenolic antioxidants. J Food Protect, 42: 858–861.
Robach MC, Pierson MD (1978) Influence of para-hydroxybenzoic acid esters on the growth and toxin production of Clostridium botulinum 10755A. J Food Sci, 43: 787–789, 792.
Roberts TA, Gibson AM, Robinson A (1981) Factors controlling the growth of Clostridium botulinum types A and B in pasteurized, cured meats. II. Growth in pork slurries prepared from “high” pH meat (range 6.3–6.8). J Food Technol, 16: 267–281.
Roberts TA, Gibson AM, Robinson A (1982) Factors controlling the growth of Clostridium botulinum types A and B in pasteurized, cured meats. III. The effect of potassium sorbate. J Food Technol, 17: 307–326.
Roberts TA, Ingram M (1966) The effect of sodium chloride, potassium nitrate and sodium nitrite on the recovery of heated bacterial spores. J Food Technol, 1: 147–163.
Roberts TA, Smart JL (1974) Inhibition of spores of Clostridium spp. by sodium nitrite. J Appl Bacteriol, 37: 261–264.
Ronning IE, Frank HA (1988) Growth response of putrefactive anaerobe 3679 to combinations of potassium sorbate and some common curing ingredients (sucrose, salt, and nitrite), and to noninhibitory levels of sorbic acid. J Food Protect, 51: 651–654.
Ronning IE, Frank HA (1987) Growth inhibition of putrefactive anaerobe 3679 caused by stringenttype response induced by protonophoric activity of sorbic acid. Appl Environ Microbiol, 53: 1020–1027.
Rose NL, Palcic MM, Sporns P, McMullen LM (2002) Nisin: A novel substrate for glutathione S-transferase isolated from fresh beef. J Food Sci, 67: 2288–2293.
Sabah JR, Thippareddi H, Marsden JL, Fung DYC (2003) Use of organic acids for the control of Clostridium perfringens in cooked vacuum-packaged restructured roast beef during an alternative cooling procedure. J Food Protect, 66: 1408–1412.
Sahl HG, Kordel M, Benz R (1987) Voltage-dependent depolarization of bacterial membranes and artificial lipid bilayers by the peptide antibiotic nisin. Arch Microbiol, 149: 120–124.
Savage RA, Stumbo CR (1971) Characteristics of progeny of ethylene oxide treated Clostridium botulinum type 62A spores. J Food Sci, 36: 182–184.
Sapers GM, Sites JE (2003) Efficacy of 1% hydrogen peroxide wash in decontaminating apples and cantaloupe melons. J Food Sci, 68: 1793–1797.
Sapers GM, Miller RL, Jantschke M, Mattrazzo AM (2000) Factors limiting the efficacy of hydrogen peroxide washes for decontamination of apples containing Escherichia coli. J Food Sci, 65: 529–532.
Schillinger U, Geisen R, Holzapfel WH (1996) Potential of antagonistic microorganisms and bacteriocins for the biological preservation of foods. Trends Food Sci Technol, 7: 158–164.
Schuenzel KM, Harrison MA (2002) Microbial antagonists of foodborne pathogens on fresh, minimally processed vegetables. J Food Protect, 65: 1909–1915.
Scott VN, Taylor SL (1981) Effect of nisin on the outgrowth of Clostridium botulinum spores. J Food Sci, 46: 117–120, 126.
Senne MM, Gilliland SE (2003) Antagonistic action of cells of Lactobacillus delbrueckii subsp. lactis against pathogenic and spoilage microorganisms in fresh meat systems. J Food Protect, 66: 418–425.
Setlow B, Loshon CA, Genest PC, Cowan AW, Setlow C, Setlow P (2002) Mechanisms of killing spores of Bacillus subtilis by acid, alkali and ethanol. J Appl Microbiol, 92: 362–375.
Seward RA, Deibel RH, Lindsay RC (1982) Effects of potassium sorbate and other antibotulinal agents on germination and outgrowth of Clostridium botulinum type E spores in microcultures. Appl Environ Microbiol, 44: 1212–1221.
Shahidi F, Rubin LJ, Diosady LL, Chew V, Wood DF (1984) Preparation of dinitrosyl ferrohemochrome from hemin and sodium nitrite. Can Inst Food Sci Technol J, 17: 33–37.
Shelef LA (1994) Antimicrobial effects of lactates: A review. J Food Protect, 57: 445–450.
Shelef LA, Seiter JA (1993) Indirect antimicrobials. In: Davidson PM (ed) Antimicrobials in Foods (2nd ed). Marcel Dekker, New York, pp. 539–569.
Shelef LA (1983) Antimicrobial effects of spices. J Food Safety, 6: 29–44.
Shelef LA, Liang P (1982) Antibacterial effects of butylated hydroxyanisole (BHA) against Bacillus species. J Food Sci, 47: 796–799.
Shelef LA, Naglik OA, Bogen DW (1980) Sensitivity of some common food-borne bacteria to the spices sage, rosemary, and allspice. J Food Sci, 45: 1042–1044.
Sofos JN (1989) Sorbate Food Preservatives. CRC Press, Boca Raton, FL.
Sofos JN, Busta FF, Allen CE (1980) Influence of pH on Clostridium botulinum control by sodium nitrite and sorbic acid in chicken emulsions. J Food Sci, 45: 7–12.
Sofos JN, Busta FF, Bhothipaksa K, Allen CE, Robach MC, Paquette MW (1980) Effects of various concentrations of sodium nitrite and potassium sorbate on Clostridium botulinum toxin production in commercially prepared bacon. J Food Sci, 45: 1285–1292.
Splittstoesser DF, Wilkison M (1973) Some factors affecting the activity of diethylpyrocarbonate as a sterilant. Appl Microbiol, 25: 853–857.
Swartling P, Lindgren B (1968) The sterilizing effect against Bacillus subtilis spores of hydrogen peroxide at different temperatures and concentrations. J Dairy Res, 35: 423–428.
Tanaka N, Gordon NM, Lindsay RC, Meske LM, Doyle MP, Traisman E (1985) Sensory characteristics of reduced nitrite bacon manufactured by the Wisconsin process. J Food Protect, 48: 687–692.
Tanaka N, Meske L, Doyle MP, Traisman E, Thayer DW, Johnston RW (1985) Plant trials of bacon made with lactic acid bacteria, sucrose and lowered sodium nitrite. J Food Protect, 48: 679–686.
Tanaka N, Traisman E, Lee MH, Cassens RG, Foster EM (1980) Inhibition of botulinum toxin formation in bacon by acid development. J Food Protect, 43: 450–457.
Tarr HLA, Southcott BA, Bissett HM (1952) Experimental preservation of flesh foods with antibiotics. Food Technol, 6: 363–368.
Thompson DP, Metevia L, Vessel T (1993) Influence of pH alone and in combination with phenolic antioxidants on growth and germination of mycotoxigenic species of Fusarium and Penicillium. J Food Protect, 56: 134–138.
Toledo RT (1975) Chemical sterilants for aseptic packaging. Food Technol, 29(5): 102–107.
Toledo RT, Escher FE, Ayres JC (1973) Sporicidal properties of hydrogen peroxide against food spoilage organisms. Appl Microbiol, 26: 592–597.
Tompkin RB (1983) Nitrite. In: Branen AL, Davidson PM (eds) Antimicrobials in Foods. Marcel Dekker, New York, pp. 205–206.
Tompkin RB, Christiansen LN, Shaparis AB (1978) Enhancing nitrite inhibition of Clostridium botulinum with isoascorbate in perishable canned cured meat. Appl Environ Microbiol, 35: 59–61.
Tompkin RB, Christiansen LN, Shaparis AB (1978) Causes of variation in botulinal inhibition in perishable canned cured meat. Appl Environ Microbiol, 35:886–889.
Tompkin RB, Christiansen LN, Shaparis AB (1979) Iron and the antibotulinal efficacy of nitrite. Appl Environ Microbiol, 37: 351–353.
Tompkin RB, Christiansen LN, Shaparis AB (1980) Antibotulinal efficacy of sulfur dioxide in meat. Appl Environ Microbiol, 39: 1096–1099.
Torriani S, Orsi C, Vescova M (1997) Potential of Lactobacillus casei culture permeate, and lactic acid to control microorganisms in ready-to-use vegetables. J Food Protect, 60: 1564–1567.
Ukuku DO, Sapers GM (2001) Effect of sanitizer treatments on Salmonella Stanley attached to the surface of cantaloupe and cell transfer to fresh-cut tissues during cutting practices. J Food Protect, 64: 1286–1292.
Vareltzis K, Buck EM, Labbe RG (1984) Effectiveness of a betalains/potassium sorbate system versus sodium nitrite for color development and control of total aerobes, Clostridium perfringens and Clostridium sporogenes in chicken frankfurters. J Food Protect, 47: 532–536.
Vas K, Ingram M (1949) Preservation of fruit juices with less SO2. Food Manuf, 24: 414–416.
Venkitanarayanan KS, Ezeike GO, Hung YC, Doyle MP (1999) Efficacy of electrolyzed oxiding water for inactivating Escherichia coli 0157:H7, Salmonella Enteritidis, and Listeria monocytogenes. Appl Environ Microbiol, 65: 4276–4279.
Wagner MK, Busta FF (1983) Effect of sodium acid pyrophosphate in combination with sodium nitrite or sodium nitrite/potassium sorbate on Clostridium botulinum growth and toxin production in beef/pork frankfurter emulsions. J Food Sci, 48: 990–991, 993.
Wang IN, Smith DL, Young R (2000) Holins: The protein clocks of bacteriophage infections. Ann Rev Microbiol, 54: 799–825.
Weissinger WR, Watters KH, Beuchat LR (2001) Evaluation of volatile chemical treatments for lethality to Salmonella on alfalfa seeds and sprouts. J Food Protect, 64: 442–450.
Weissinger WR, Beuchat LR (2000) Comparison of aqueous chemical treatments to eliminate Salmonella on alfalfa seeds. J Food Protect, 63: 1475–1482.
Wickramanayake GB, Rubin AJ, Sproul OJ (1984) Inactivation of Giardia lamblia Cysts with Ozone. Appl Environ Microbiol, 48:671–672.
Winarno FG, Stumbo CR (1971) Mode of action of ethylene oxide on spores of Clostridium botulinum 62A. J Food Sci, 36: 892–895.
Wisniewsky MA, Glatz BA, Gleason ML, Reitmeier CA (2000) Reduction of Escherichia coli O157:H7 counts on whole fresh apples by treatment with sanitizers. J Food Protect, 63: 703–708.
Wood DS, Collins-Thompson DL, Usborne WR, Pickard B (1986) An evaluation of antibotulinal activity in nitrite-free curing systems containing dinitrosyl ferrohemochrome. J Food Protect, 49: 691–695.
Woods LFJ, Wood JM (1982) A note on the effect of nitrite inhibition on the metabolism of Clostridium botulinum. J Appl Bacteriol, 52: 109–110.
Woods LFJ, Wood JM, Gibbs PA (1981) The involvement of nitric oxide in the inhibition of the phosphoroclastic system in Clostridium sporogenes by sodium nitrite. J Gen Microbiol, 125: 399–406.
Wu FM, Doyle MP, Beuchat LR, Wells JG, Mintz ED, Swaminathan B (2000) Fate of Shigella sonnei on parsley and methods of disinfection. J Food Protect, 63: 568–572.
Xu L (1999) Use of ozone to improve the safety of fresh fruits and vegetables. Food Technol, 53(10): 58–61, 63.
Yamazaki K, Suzuki M, Kawai Y, Inoue N, Montville TJ (2003) Inhibition of Listeria monocytogenes in coldsmoked salmon by Carnobacterium piscicola CS526 isolated from frozen surimi. J Food Protect, 66: 1420–1425.
Yang H, Svem BL, Li Y (2003) The effect of pH on inactivation of pathogenic bacteria on freshcut lettuce by dipping treatment with electrolyzed water. J Food Sci, 68: 1013–1017.
Yarbrough JM, Rake JB, Egon RG (1980) Bacterial inhibitory effects of nitrite: Inhibition of active transport, but not of group translocation, and of intracellular enzymes. Appl Environ Microbiol, 39: 831–834.
Young R, Bläsi U (1995) Holins: Form and function in bacteriophage lysis. FEMS Microbiol Rev, 17: 191–205.
Young SB, Setlow P (2003) Mechanisms of killing of Bacillus subtilis spores by hypochlorite and chlorine dioxide. J Appl Microbiol, 95: 54–67.
Yun J, Shahidi F, Rubin LJ, Diosady LL (1987) Oxidative stability and flavour acceptability of nitrite-free curing systems. Can Inst Food Sci Technol J, 20: 246–251.
Zaika LL, Kissinger JC, Wasserman AE (1983) Inhibition of lactic acid bacteria by herbs. J Food Sci, 48: 1455–1459.
Zaika LL, Scullen OJ, Fanelli JS (1997) Growth inhibition of Listeria monocytogenes by sodium polyphosphate as affected by polyvalent metal ions. J Food Sci, 62: 867–869, 872.
Zessin KG, Shelef LA (1988) Sensitivity of Pseudomonas strains to polyphosphates in media systems. J Food Sci, 53: 669–670.
Zimmer M, Vukov N, Scherer S, Loessner MJ (2002) The murein hydrolase of the bacteriophage o3626 dual lysis system is active against all tested Clostridium perfringens strains. Appl Environ Microbiol, 68: 5311–5317.
Zivanovic S, Basurto CC, Chi S, Davidson PM, Weiss J (2004) Molecular weight of chitosan influences — antimicrobial activity in oil-in-water emulsions. J Food Protect, 67: 952–959.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2009 Springer-Verlag Italia
About this chapter
Cite this chapter
(2009). Protezione degli alimenti mediante sostanze chimiche e sistemi di biocontrollo. In: Pulvirenti, A. (eds) Microbiologia degli alimenti. Food. Springer, Milano. https://doi.org/10.1007/978-88-470-0786-4_13
Download citation
DOI: https://doi.org/10.1007/978-88-470-0786-4_13
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-0785-7
Online ISBN: 978-88-470-0786-4
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)