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Predisposition to Sepsis

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Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.

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Abstract

Sepsis is defined as the host response to invasive infection [1]. But while the trigger — infection — typically originates outside the host, the response that drives the phenotype of the illness arises endogenously. As a consequence, it is highly, and perhaps counterintuitively, shaped by pre-existing factors within the host that predispose him or her to a distinctive risk of acquiring infection, and having acquired that infection, of surviving the acute illness.

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Authors and Affiliations

  1. Department of Surgery, and the Interdepartmental Division of Critical Care Medicine, University of Toronto, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario, Canada

    J. C. Marshall

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Editors and Affiliations

  1. Department of Anaesthesia and Intensive Care Head, Postgraduated School of Anaesthesia and Intensive Care, Catania University Hospital, Catania, Italy

    Antonino Gullo M.D. (Head) (Head)

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Marshall, J.C. (2008). Predisposition to Sepsis. In: Gullo, A. (eds) Anaesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/978-88-470-0773-4_22

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  • DOI: https://doi.org/10.1007/978-88-470-0773-4_22

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