Biliary Lithiasis in Patients with Gastroesophageal Reflux (Acid and Alkaline)

  • Alberto del Genio
  • Gianluca Rossetti
  • Vincenzo Maffettone
  • Vincenzo Napolitano
  • Gianmattia del Genio
  • Luigi Brusciano
  • Francesco Pizza
  • Maria Di Martino
  • Salvatore Tolone


Gastroesophageal reflux (GERD) and cholelithiasis are both very common diseases. It is estimated that 15–20 million people in the United States have gallstones [1] and that 36% of the American population complains of at least one episode of heart-burn per month. In Spain, 10% of the population has ultrasonographically demonstrated cholelithiasis [2] and 30% of the population suffers from reflux symptoms, 10% of these on a weekly basis [3]. The two diseases have been connected for years. Saint’s triad [4], a well-known association of hiatal hernia with cholelithiasis and colon diverticula that was much in fashion during the 1980s, represented a paradigmatic expression of Westernization-induced gastrointestinal disturbances. However, this argument is very contentious, and we will try to analyze the controversy in this chapter.


Gastric Emptying Hiatal Hernia Gastroesophageal Reflux Lower Esophageal Sphincter Gallstone Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Alberto del Genio
    • 1
  • Gianluca Rossetti
    • 1
  • Vincenzo Maffettone
    • 1
  • Vincenzo Napolitano
    • 1
  • Gianmattia del Genio
    • 1
  • Luigi Brusciano
    • 1
  • Francesco Pizza
    • 1
  • Maria Di Martino
    • 1
  • Salvatore Tolone
    • 1
  1. 1.I Division of General and Gastrointestinal SurgerySecond University of NaplesNaplesItaly

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