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Biliary Lithiasis in Patients with Gastroesophageal Reflux (Acid and Alkaline)

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Biliary Lithiasis

Abstract

Gastroesophageal reflux (GERD) and cholelithiasis are both very common diseases. It is estimated that 15–20 million people in the United States have gallstones [1] and that 36% of the American population complains of at least one episode of heart-burn per month. In Spain, 10% of the population has ultrasonographically demonstrated cholelithiasis [2] and 30% of the population suffers from reflux symptoms, 10% of these on a weekly basis [3]. The two diseases have been connected for years. Saint’s triad [4], a well-known association of hiatal hernia with cholelithiasis and colon diverticula that was much in fashion during the 1980s, represented a paradigmatic expression of Westernization-induced gastrointestinal disturbances. However, this argument is very contentious, and we will try to analyze the controversy in this chapter.

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References

  1. Marshall JB (1994) Current opinions in gallstone management. What to do when symptoms are mild or absent. Postgrad Med 95:115–128

    PubMed  CAS  Google Scholar 

  2. Martinez de Pancorbo C, Carballo F, Horcajo P et al (1997) Prevalence and associated factors for gallstone disease: results of a population survey in Spain. J Clin Epidemiol 50:1347–1355

    Article  PubMed  CAS  Google Scholar 

  3. Diaz-Rubio M, Moreno-Elola-Olaso C, Rey E et al (2004) Symptoms of gastroesophageal reflux: prevalence, severity duration and associated factors in a Spanish population. Aliment Pharmacol Ther 19:95–106

    Article  PubMed  CAS  Google Scholar 

  4. Burkitt DP, Walker ARP (1976) Saint’s triad: confirmation and explanation. S Afr Med J 50:2136

    PubMed  CAS  Google Scholar 

  5. Fisher RS, Stelzer F, Rock E, Malmud LS (1982) Abnormal gallbladder emptying in patients with gallstones. Dig Dis Sci 27:1019–1024

    Article  PubMed  CAS  Google Scholar 

  6. Portincasa P, Di Ciaula A, Baldassarre G et al (1994) Gallbladder motor function in gallstone patients: sonographic and in vitro studies on the role of gallstones, smooth muscle function and gallbladder wall inflammation. J Hepatol 21:430–440

    Article  PubMed  CAS  Google Scholar 

  7. Pomeranz IS, Shaffer EA (1985) Abnormal gallbladder emptying in a subgroup of patients with gallstones. Gastroenterology 88:787–791

    PubMed  CAS  Google Scholar 

  8. Van Erpecum KJ, van Berge-Henegouwen GP, Stolk MFJ et al (1992) Fasting gallbladder volume, postprandial emptying and cholecystokinin release in gallstone patients and normal subjects. J Hepatol 14:194–202

    Article  PubMed  Google Scholar 

  9. Stolk MFJ, van Erpecum KJ, Renooij W et al (1995) Gallbladder emptying in vivo, bile composition and nucleation of cholesterol crystals in patients with cholesterol gallstones. Gastroenterology 108:1882–1888

    Article  PubMed  CAS  Google Scholar 

  10. Klapdor R, Hammer E (1983) Interdigestive motilin secretion and gallstone disease. Klin Wochenschr 61:251–253

    Article  PubMed  CAS  Google Scholar 

  11. Heaton KW, Emmett PM, Symes CL, Braddon FEM (1993) An explanation for gallstones in normal-weight women: slow intestinal transit. Lancet 341:8–10

    Article  PubMed  CAS  Google Scholar 

  12. Jazrawi S, Walsh TN, Byrne PJ et al (1993) Cholecystectomy and esophageal reflux: a prospective evaluation. Br J Surg 80:50–53

    Article  PubMed  CAS  Google Scholar 

  13. Portincasa P, Di Ciaula A, Palmieri V et al (1997) Impaired gallbladder and gastric motility and pathological gastroesophageal reflux in gallstone patients. Eur J Clin Invest 27:653–661

    Article  PubMed  CAS  Google Scholar 

  14. Ibrarullah M, Mittal BR, Agarwal DK et al (1994) Gastric emptying in patients with gallstone disease with or without dyspepsia: effect of cholecystectomy. Aust N Z J Surg 64:247–250

    Article  PubMed  CAS  Google Scholar 

  15. Walker JP, Khalil T, Wiener I et al (1985) The role of neurotensin in human gallbladder motility. Ann Surg 201:678–683

    Article  PubMed  CAS  Google Scholar 

  16. Blackburn AM, Bloom SR, Long RG (1980) Effect of neurotensin on gastric function in man. Lancet 1:987–989

    Article  PubMed  CAS  Google Scholar 

  17. Rosell S, Thor K, Nyquist O et al (1980) Plasma concentration of neurotensin-like immunoreactivity and lower esophageal sphincter pressure in man following infusion of (Gln4)-neurotensin. Acta Physiol Scand 109:369–375

    Article  PubMed  CAS  Google Scholar 

  18. Wilson P, Welch NT, Hinder RA et al (1993) Abnormal plasma gut hormones in pathologic duodenogastric reflux and their response to surgery. Am J Surg 165:169–176

    Article  PubMed  CAS  Google Scholar 

  19. Capron JP, Payenneville H, Dumont M et al (1978) Evidence for an association between cholelithiasis and hiatus hernia. Lancet 2:329–331

    PubMed  CAS  Google Scholar 

  20. Baldwin JA (1978) Cholithiasis and hiatus hernia. Lancet 2:992

    Article  PubMed  CAS  Google Scholar 

  21. Honorf LH (1979) Cholelithiasis and hiatus hernia. Lancet 2:927–928

    Article  Google Scholar 

  22. Avidan B, Sonnenberg A, Schnell TG, Sontag SJ (2001) No association between gallstones and gastroesophageal reflux disease. Am J Gastroenterol 96:2858–2862

    Article  PubMed  CAS  Google Scholar 

  23. Svensson JO, Gelin J, Svanvik J (1986) Gallstones, cholecystectomy and duodenogastric reflux of bile acid. Scand J Gastroenterol 21:181–187

    Article  PubMed  CAS  Google Scholar 

  24. Cabrol J, Navarro X, Simo-Deu J, Segura R (1990) Evaluation of duodenogastric reflux in gallstone disease before and after simple cholecystectomy. Am J Surg 160:283–286

    Article  PubMed  CAS  Google Scholar 

  25. Bates T, Ebbs SR, Harrison M, A’Hern RP (1991) Influence of cholecystectomy on symptoms. Br J Surg 78:964–967

    Article  PubMed  CAS  Google Scholar 

  26. Brough WA, Taylor TV, Torrance HB (1984) The surgical factors influencing duodenogastric reflux. Br J Surg 71:770–773

    Article  PubMed  CAS  Google Scholar 

  27. Lorusso D, Mangini V, Misciagna G et al (1986) Pre-and postcholecystectomy duodenogastric reflux. Dig Surg 3:305–310

    Article  Google Scholar 

  28. Pedrikis G, Wilson P, Hinder R et al (1994) Altered antroduodenal motility after cholecystectomy. Am J Surg 168:609–615

    Article  Google Scholar 

  29. Bailey I, Walsh TN, Hill AD et al (1992) Effect of cholecystectomy on plasma cholecystokinin. Br J Surg 79:456

    Google Scholar 

  30. McDonnell CO, Bailey I, Stumpf T et al (2002) The effect of cholecystectomy on plasma cholecystokinin. Am J Gastroenterol 97:2189–2192

    Article  PubMed  CAS  Google Scholar 

  31. Clavè P, Gonzalez A, Martin M et al (1996) Endogenous cholecystokinin enhances post-prandial gastroesophageal reflux in healthy volunteers. Gastroenterology 4:A649

    Google Scholar 

  32. Lorusso D, Misciagna G, Mangini V et al (1990) Duodenogastric reflux of bile acids, gastrin and parietal cells and gastric acid secretion before and 6 months after cholecystectomy. Am J Surg 159:575–578

    Article  PubMed  CAS  Google Scholar 

  33. Jazrawi S, Walsh TN, Byrne PJ et al (1993) Cholecystectomy and esophageal reflux: a prospective evaluation. Br J Surg 80:50–53

    Article  PubMed  CAS  Google Scholar 

  34. Lujan-Mompean JA, Robles-Campos R, Parrilla-Paricio P et al (1993) Duodenogastric reflux in patients with biliary lithiasis before and after cholecystecomy. Surg Gynecol Obstet 176:116–118

    PubMed  CAS  Google Scholar 

  35. Rothwell JF, Lawlor P, Byrne PJ et al (1997) Cholecystectomy induced gastroesophageal reflux: is it reduced by the laparoscopic approach? Am J Gastroenterol 92:1351–1354

    PubMed  CAS  Google Scholar 

  36. Maddern GJ, Baxter PS (1997) The effect of laparoscopic cholecystectomy on gastroduodenal reflux. Aust N Z J Surg 67:703–705

    Article  PubMed  CAS  Google Scholar 

  37. Manifold DK, Anggiansah B, Owen WJ (2000) Effect of cholecystectomy on gastroesophageal and duodenogastric reflux. Am J Gastroenterol 95:2746–2750

    PubMed  CAS  Google Scholar 

  38. Ransohoff DF, Gracie WA (1993) Treatment of gallstones. Ann Intern Med 119:606–619

    PubMed  CAS  Google Scholar 

  39. Peterson R (1995) Gallstones during the course of 1066 abdominal sections for pelvic disease. Surg Gynecol Obstet 20:284–291

    Google Scholar 

  40. Lund J (1960) Surgical indication in cholelithiasis: prophylactic cholecystectomy elucidated on the basis of long-term follow up on 526 non operated cases. Ann Surg 151:153–162

    Article  PubMed  CAS  Google Scholar 

  41. Wenckert A, Robertson B (1966) The natural course of gallstone disease: eleven-year review of 781 non operated cases. Gastroenterology 50:376–381

    PubMed  CAS  Google Scholar 

  42. Klaus A, Hinder R, Swain J, Achem SR (2002) Incidental cholecystectomy during laparoscopic antireflux surgery. Am Surg 68:619–62

    PubMed  Google Scholar 

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del Genio, A. et al. (2008). Biliary Lithiasis in Patients with Gastroesophageal Reflux (Acid and Alkaline). In: Biliary Lithiasis. Springer, Milano. https://doi.org/10.1007/978-88-470-0763-5_34

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  • DOI: https://doi.org/10.1007/978-88-470-0763-5_34

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0762-8

  • Online ISBN: 978-88-470-0763-5

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