Abstract
Gallbladder cancer is the most common malignant neoplasm of the biliary tract [1, 2]. The reported incidence of incidental gallbladder carcinoma during or after laparoscopic cholecystectomy ranges from 0.2% to 0.6% [3–5]. Most incidental gallbladder carcinomas are T1 (tumor invading the lamina propria or muscle layer). Despite recent progress in diagnostic techniques and equipment, preoperative diagnosis of gallbladder cancer is often difficult, especially if gallstone disease is present and tumor invasion is limited to the gallbladder wall [6]. If gallbladder cancer is suspected intraoperatively, the diagnostic accuracy of the frozen section is high, but the frozen section yields less reliable information about the depth of tumor invasion (T) [7].
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References
Misra S, Chaturvedi A, Misra NC, Sharma ID (2003) Carcinoma of the gallbladder. Lancet Oncol 4:167–176
Reid KM, De la Medina AR, Donohue JH (2007) Diagnosis and surgical management of gallbladder cancer: a review. J Gastrointest Surg 11:671–681
Antonakis P, Alexakis N, Mylonaki D et al (2003) Incidental finding of gallbladder carcinoma detected during or after laparoscopic cholecystectomy. Eur J Surg Oncol 29:358–360
Chan CP, Chang HC, Chen YL et al (2003) A 10-year experience of unsuspected gallbladder cancer after laparoscopic cholecystectomy. Int Surg 88:175–179
Contini S, Dalla Valle R, Zinicola R (1999) Unexpected gallbladder cancer after laparoscopic cholescystectomy. An emerging problem? Reflections on four cases. Surg Endosc 13:264–267
Onoyama H, Yamamoto M, Takada M et al (1999) Diagnostic imaging of early gallbladder cancer: retrospective study of 53 cases. World J Surg 23:708–712
Yamaguchi K, Chijiva K, Saiki S et al (1997) Reliability of frozen section diagnosis of gallbladder tumor for detecting carcinoma and depth of its invasion. J Surg Oncol 65:132–136
Benoist S, Panis Y, Fagniez PL and the French University Association for Surgical Research (1998) Long-term results after curative resection for carcinoma of the gallbladder. Am J Surg 175:118–122
Muratore A, Polastri R, Bouzari H et al (2000) Radical surgery for gallbladder cancer: a worthwhile operation? Eur J Surg Oncol 26:160–163
Shirai Y, Yoshida K, Tsukada K et al (1992) Early carcinoma of the gallbladder. Eur J Surg 158:545–548
Cubertafond P, Mathonnet M, Gainant A, Launois B (1999) Radical surgery for gallbladder cancer: Results of the French Surgical Association Survey. Hepatogastroenterology 46:1567–1571
Ouchi K, Sugawara T, Ono H et al (1999) Diagnostic capability and rational resectional surgery for early gallbladder cancer. Hepatogastroenterology 46:1557–1560
Wakai T, Shirai Y, Yokoyama N et al (2001) Early gallbladder carcinoma does not warrant radical resection. Br J Surg 88:675–678
Wagholikar GD, Behari A, Krishnani N et al (2002) Early gallbladder cancer. J Am Coll Surg 194:137–141
Ogura Y, Mizumoto R, Isaji S et al (1991) Radical operations for carcinoma of the gallbladder. World J Surg 15:337–343
Muratore A, Amisano M, Viganò L et al (2003) Gallbladder cancer invading the perimuscular conective tissue: results of reresection after prior non-curative operation. J Surg Oncol 83:212–215
Muratore A, Polastri R, Capussotti L (2000) Radical surgery for gallbladder cancer: current options. Eur J Surg Oncol 26:438–443
Hirai Y, Tsukada K, Ohtani T et al (1995) Hepatic metastases from carcinoma of the gallbladder. Cancer 75:2063–2068
Yoshikawa T, Araida T, Azuma T, Takasaki K (1998) Bisubsegmental liver resection for gallbladder cancer. Hepatogastroenterology 45:14–19
Tsukada K, Kurosaki I, Uchida K et al (1997) Lymph node spread from carcinoma of the gallbladder. Cancer 80:661–667
Bartlett DL, Fong Y, Fortner JG et al (1996) Longterm results after resection for gallbladder cancer: implications for staging and management. Ann Surg 5:639–646
Cubertafond P, Gainant A, Cucchiaro G (1994) Surgical treatment of 724 carcinomas of the gallbladder: results of the French Surgical Association Survey. Ann Surg 219:275–280
Yamaguchi K, Chijiwa K, Saiki K et al (1997) Retrospective analysis of 70 operations for gallbladder carcinoma. Br J Surg 84:200–204
Shirai Y, Yoshida K, Tsukada K, Muto T (1992) Inapparent carcinoma of gallbladder. An appraisal of radical second operation after simple cholecystectomy. Ann Surg 215:326–331
Wakai T, Shirai Y, Hatakeyama K (2002) Radical second resection provides survival benefit for patients with T2 gallbladder carcinoma first discovered after laparoscopic cholecystectomy. World J Surg 26:867–871
De Aretxabala X, Roa I, Burgos L et al (2006) Gallbladder cancer: an analysis of a series of 139 patients with invasion restricted to the subserosal layer. J Gastrointest Surg 10:186–192
Paolucci V, Schaeff B, Schneider M, Gutt C (1999) Tumor seeding following laparocopy: international survey. World J Surg 23:989–997
Lundberg O, Kristofferson A (1999) Port site metastases from gallbladder cancer after laparoscopic cholecystectomy. Results of a Swedish survey and review of published reports. Eur J Surg 165:215–222
Yamaguchi K, Chijiiwa K, Ichimiya H et al (1996) Gallbladder carcinoma in the era of laparoscopic cholecystectomy. Arch Surg 131:981–984
Doudle M, King G, Thomas WM, Hewett P (1996) The movement of mucosal cells of the gallbladder within the peritoneal cavity during laparoscopic cholecystectomy. Surg Endosc 10:1092–1094
Bouvy ND, Marquet RL, Jeekel J, Bonier HJ (1997) Laparoscopic surgery is associated with less tumor growth stimulation than conventional surgery: an experimental study. Br J Surg 84:358–361
Aoki Y, Shimura H, Li H et al (1999) A model of port-site metastases of gallbladder cancer: the influence of peritoneal injury and its repair on abdominal wall metastases. Surgery 125:553–559
Tsukada K, Hatakeyama K, Kurosaki I et al (1996) Outcome of radical surgery for carcinoma of the gallbladder according to the TNM stage. Surgery 120:816–822
Shimada H, Endo I, Togo S et al (1997) The role of lymph node dissection in the treatment of gallbladder carcinoma. Cancer 79:892–899
Kosuge T, Sano K, Shimada K et al (1999) Should the bile duct be preserved or removed in radical surgery for gallbladder cancer. Hepatogastroenterology 46:2133–2137
Yokomizo H, Yamane T, Hirata T et al (2007) Surgical treatment of pT2 gallbladder carcinoma: a reevaluation of the therapeutic effect of hepatectomy and extrahepatic bile duct resection based on the long-term outcome. Ann Surg Oncol 14:1366–1373
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Capussotti, L., Muratore, A., Ferrero, A., Viganò, L. (2008). Incidental Carcinoma of the Gallbladder. In: Biliary Lithiasis. Springer, Milano. https://doi.org/10.1007/978-88-470-0763-5_20
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DOI: https://doi.org/10.1007/978-88-470-0763-5_20
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-0762-8
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