Cardiac MRI in Diagnosis of Myocardial Disease in HIV-Infected Patients

  • J. Garot


The heart and great vessels are not the sites most frequently affected by opportunistic infections or tumors in patients with AIDS. However, cardiovascular complications are relatively common and may be responsible for sudden death. A wide spectrum of cardiovascular complications have been reported in HIV infection and AIDS, which may be depicted at imaging, including pericardial disease with effusion and tamponade, nonspecific or infectious myocarditis, dilated cardiomyopathy with global left ventricular dysfunction, endocardial valvular disease due to marantic or infective endocarditis, arrhythmias, human immunodeficiency virus-associated pulmonary hypertension, thrombosis, embolism, vasculitis, coronary artery disease, aneurysm, and cardiac involvement in AIDS-related tumors. However, more specifically, myocardial involvement in HIV seropositive patients is multifactorial and associated with increased morbidity and mortality. Classically, a variety of potential aetiologies have been postulated in HIV-related myocardial diseases, ultimately leading to cardiomyopathy, which include myocardial infection with HIV itself, opportunistic infections, viral infections, autoimmune response to viral infection, drug-related cardiotoxicity, ischemic myocardial damage, nutritional deficiencies, and prolonged immunosuppression. Of note, the epidemiology has changed dramatically since the introduction of highly active antiretroviral therapy (HAART). Coronary artery disease and dyslipidaemia, drugrelated cardiotoxicity and cardiac autonomic dysfunction are becoming increasingly prevalent.


Cardiovascular Magnetic Resonance Dilate Cardiomyopathy Infective Endocarditis Pericardial Effusion Microvascular Obstruction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia 2009

Authors and Affiliations

  • J. Garot
    • 1
  1. 1.Fédération de CardiologieHôpital Henri MondorCréteilFrance

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