Many staging systems have been proposed for hilar cholangiocarcinoma and none of them has been accepted unanimously.
  • Three different types of classification have been suggested:

  • Classification based on macroscopic biliary involvement (Bismuth-Corlette)

  • Histopathologic classification (TNM AJCC/UICC and Japanese Society for Biliary Surgery, JSBS)

  • Classification based on biliary and vascular involvement (Gazzaniga and Memorial Sloan Kettering Cancer Center, MSKCC)


Portal Vein Staging System Biliary Duct Hilar Cholangiocarcinoma Intrahepatic Cholangiocarcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Bismuth H, Corlette MB (1975) Intrahepatic cholangioenteric anastomosis in carcinoma of the hilus of the liver. Surg Gynecol Obstet 140(2):170–178PubMedGoogle Scholar
  2. 2.
    Bismuth H, Nakache R, Diamond T (1992) Management strategies in resection for hilar cholangiocarcinoma. Ann Surg 199 215(1):31–38CrossRefGoogle Scholar
  3. 3.
    Zervos EE, Osborne D, Goldin SB et al (2005) Stage does not predict survival after resection of hilar cholangiocarcinomas promoting an aggressive operative approach. Am J Surg 190(5):810–815PubMedCrossRefGoogle Scholar
  4. 4.
    Sobin LH, Wittekind C (eds) (2002) TNM classification of malignant tumours, 6th edn. Wiley, New YorkGoogle Scholar
  5. 5.
    Nishio H, Nagino M, Oda K et al (2005) TNM classification for perihilar cholangiocarcinoma; comparison between 5th and 6th editions of the AJCC/UICC staging system. Langenbecks Arch Surg 390(4):319–327PubMedCrossRefGoogle Scholar
  6. 6.
    Kitagawa Y, Nagino M, Kamiya J et al (2001) Lymph-node metastasis from hilar cholangiocarcinoma: audit of 110 patients who underwent regional and paraaortic node dissection. Ann Surg 233(3):385–392PubMedCrossRefGoogle Scholar
  7. 7.
    Liu CL, Fan ST, Lo CM et al. (2006) Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma. Br J Surg 93(12):1488–1494PubMedCrossRefGoogle Scholar
  8. 8.
    Hong S-M, Kim M-J, Pi DY et al (2005) Analysis of extrahepatic bile duct carcinomas according to the new American Joint Committee on Cancer Staging System focused on tumour classification problems in 222 patients. Cancer 104(4):802–810PubMedCrossRefGoogle Scholar
  9. 9.
    Ebata T, Nagino M, Kamiya J et al (2003) Hepatectomy with portal vein resection for hilar cholangiocarcinoma: audit of 52 consecutive cases. Ann Surg 238(5):720–727PubMedCrossRefGoogle Scholar
  10. 10.
    Japanese Society of Biliary Surgery (2004) Classification of biliary tract carcinoma. 2nd English edn. Kanehara, TokyoGoogle Scholar
  11. 11.
    Gazzaniga GM, Faggioni A, Bonanza G et al (1984) Classificazione anatomo-chirurgica dei tumori dell’ ilo epatico. Notiz Chir 5:128–129Google Scholar
  12. 12.
    Gazzaniga GM, Filauro M, Faggioni A et al (1986) Neoplasie primitive dell’ ilo epatico: trattamento e risultati. Chir Epatobil 5:59–63Google Scholar
  13. 13.
    Burke EC, Jarnagin WR, Hochwald SN et al (1998) Hilar Cholangiocarcinoma: patterns of spread, the importance of hepatic resection for curative operation, and a presurgical clinical staging system. Ann Surg 228(3):385–394PubMedCrossRefGoogle Scholar
  14. 14.
    Jarnagin WR, Fong Y, DeMatteo RP et al (2001) Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma. Ann Surg 234(4):507–517; discussion 517–519PubMedCrossRefGoogle Scholar

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