Abstract
Curative treatment of hilar cholangiocarcinoma leads to a major reduction of hepatic function due to the need for extended hepatectomy with biliary tract resection; therefore, it is exposed to the risk of postoperative hepatic failure [1,2]. Makuuchi [3] can take the credit, for introducing preoperative embolic occlusion of portal branches (PVE) in patients with hilar cholangiocarcinoma to stimulate compensatory hypertrophy of the future remnant liver (FRL) and prevent the sudden increase of portal pressure after hepatectomy. Diversion of portal flow following PVE entails an improvement of the functional reserve of residual liver and allows extending the indications for surgical therapy even in patients with a marginal hepatic function.
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Guglielmi, A., Ruzzenente, A., Iacono, C. (2008). Preoperative Portal Vein Embolization. In: Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-0729-1_7
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DOI: https://doi.org/10.1007/978-88-470-0729-1_7
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