Abstract
Cholangiocarcinoma is a malignant tumour composed of cells resembling those of the bile ducts. According to WHO classification[1] the term cholangiocarcinoma is reserved for carcinomas arising in the intrahepatic bile ducts. For this reason, tumours arising from extrahepatic bile ducts should be designated as extrahepatic bile duct carcinomas. However clinical and pathological differentiation of intrahepatic from extrahepatic bile duct cancers can be difficult. Cancers arising from the bile duct epithelium of the right and left hepatic ducts and at the bifurcation are also considered cholangiocarcinomas and are called “hilar cholangiocarcinomas”. Intrahepatic (or peripheral) cholangiocarcinoma is a primary liver cancer and can arise from any portion of the intrahepatic bile duct epithelium[2].
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Guglielmi, A., Ruzzenente, A., Iacono, C. (2008). Reporting Cholangiocarcinoma: Pathological Aspects. In: Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-0729-1_1
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DOI: https://doi.org/10.1007/978-88-470-0729-1_1
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