Antimicrobial Resistance During 20 Years of Clinical SDD Research

  • Durk F. Zandstra
  • Hendrick K. F. van Saene
  • Peter H. J. van der Voort


Selective decontamination of the digestive tract (SDD) is probably the most investigated clinical intervention in critically ill patients treated in intensive care units (ICU). Several meta-analysis studies have been published underlining its efficacy and significance in the reduction of infections in the critically ill patient, especially of ventilator-associated pneumonia (VAP) and bloodstream infections with consequent reductions of mortality by 20% [1]–[3].


Antimicrobial Resistance Selective Digestive Decontamination Selective Decontamination Protected Specimen Brush Abnormal Flora 
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Copyright information

© Springer 2008

Authors and Affiliations

  • Durk F. Zandstra
    • 1
  • Hendrick K. F. van Saene
    • 2
  • Peter H. J. van der Voort
    • 1
  1. 1.Department of Intensive CareOnze Lieve Vrouwe GasthuisAmsterdamThe Netherlands
  2. 2.Department of Clinical Microbiology and Infection ControlRoyal Liverpool Children’s NHS Trust of Alder HeyLiverpoolUK

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