The Role of SDD in Liver Transplantation: a Meta-Analysis

  • Peter H. J. van der Voort
  • Hendrick K. F. van Saene


Wiesner et al. introduced SDD as infection prophylaxis in liver transplantation in 1987 and 1988 [1, 2]. These investigators reasoned that liver transplant recipients are the prime subset of patients to benefit from SDD prophylaxis for three reasons:
  1. 1.

    Liver transplant recipients are at high risk of infection

  2. 2.

    Most infections are endogenous following gut overgrowth

  3. 3.

    The potential pathogens causing infection in liver transplant recipients are aerobic Gram-negative bacilli (AGNB) and yeasts, the target microorganisms of SDD.



Liver Transplantation Orthotopic Liver Transplantation Liver Transplant Recipient Liver Transplant Patient Selective Digestive Decontamination 
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Copyright information

© Springer 2008

Authors and Affiliations

  • Peter H. J. van der Voort
    • 1
  • Hendrick K. F. van Saene
    • 2
  1. 1.Department of Intensive CareOnze Lieve Vrouwe GasthuisAmsterdamThe Netherlands
  2. 2.Department of Clinical Microbiology and Infection ControlRoyal Liverpool Children’s NHS Trust of Alder HeyLiverpoolUK

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