The Impact of New Imaging, Mapping and Energy Delivery Technology on the Current Approach to Ablation of Atrial Fibrillation

  • Andrea Colella
  • Marzia Giaccardi
  • Luigi Padeletti
  • Gian Franco Gensini
Conference paper


Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. It is frequently symptomatic and contributes to significant morbidity and mortality, independent of all other cardiac comorbidities [1]. Providing effective treatment of AF is one of the challenges of electrophysiology, and it is the focus of major research initiatives in the scientific community. The level of concern and interest regarding AF has increased over the years with the advent of curative ablative techniques.


Atrial Fibrillation Pulmonary Vein Pulmonary Vein Isolation Magnetic Navigation Microwave Endometrial Ablation 
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  1. 1.
    Benjamin EJ, Larson MG, Keyes MJ et al (2004) Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study. Circulation 109:613–619PubMedCrossRefGoogle Scholar
  2. 2.
    Corley SD, Epstein AE, DiMarco JP et al (2004) Relationship between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study. Circulation 109:1509–1513PubMedCrossRefGoogle Scholar
  3. 3.
    Cox JL, Schuiessler RB, Lappas DG et al (1996) An 8?-year clinical experience with surgery for atrial fibrillation. Ann Surg 224:267–273PubMedCrossRefGoogle Scholar
  4. 4.
    Keane D, Reddy V, Ruskin J (2005) Emerging concepts on catheter ablation of atrial fibrillation from the tenth annual Boston Atrial Fibrillation Symposium. J Cardiovasc Electrophysiol 16:1025–1028PubMedCrossRefGoogle Scholar
  5. 5.
    Jais P, Haissaguerre M, Shah DC et al (1997) A focal source of atrial fibrillation treated by discrete radiofrequency ablation. Circulation 95:572–576PubMedGoogle Scholar
  6. 6.
    Haissaguerre M, Jais P, Shah DC et al (1998) Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med 339:659–666PubMedCrossRefGoogle Scholar
  7. 7.
    Pappone C, Rosanio S, Oreto G et al (2000) Circumferential radiofrequency ablation of pulmonary vein ostia: a new anatomic approach for curing atrial fibrillation. Circulation 102:2619–2628PubMedGoogle Scholar
  8. 8.
    Platt M, Mandapati R, Scherlag BJ et al (2004) Limiting the number and extent of radiofrequency applications to terminate atrial fibrillation and subsequently prevent its inducibility. Heart Rhythm 1:S11 (a bs)Google Scholar
  9. 9.
    Scherlag BJ, Nakagawa H, Jackman WM et al (2005) Electrical stimulation to identify neural elements on the heart: their role in atrial fibrillation. J Interv Card Electrophysiol 13(Suppl 1):37–42PubMedCrossRefGoogle Scholar
  10. 10.
    Nademanee K, McKenzie J, Kosar E et al (2004) A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate. J Am Coll Cardiol 43:2044–2053PubMedCrossRefGoogle Scholar
  11. 11.
    Bain C, Cooper KG, Parkin DE (2002) Microwave endometrial ablation versus endometrial resection: a randomized controlled trial. Obstet Gynecol 99:983–987PubMedCrossRefGoogle Scholar
  12. 12.
    Anidjar M, Teillac P (1995) Non-surgical instrumental treatment of benign hypertrophy of the prostate. Presse Med 24:1477–1480PubMedGoogle Scholar
  13. 13.
    D’Agostino HB, Solinas A (1995) Percutaneous ablation therapy for hepatocellular carcinomas. AJR Am J Roentgenol 164:1165–1167PubMedGoogle Scholar
  14. 14.
    Miyake O, Itatani H, Itoh H et al (1995) Laser-TURP with a lateral firing fiber for contact irradiation. Nippon Hinyokika Gakkai Zasshi 86:273–278PubMedGoogle Scholar
  15. 15.
    Kigure T, Harada T, Satoh Y et al (1996) Microwave ablation of the adrenal gland: experimental study and clinical application. Br J Urol 77:215–220PubMedGoogle Scholar
  16. 16.
    Hodgson DA, Feldberg IB, Sharp N et al (1999) Microwave endometrial ablation: development, clinical trials and outcomes at three years. Br J Obstet Gynaecol 106:684–694PubMedGoogle Scholar
  17. 17.
    Korn AP (2000) Endometrial cryoablation and thermal ablation. Clin Obstet Gynecol 43:575–583PubMedCrossRefGoogle Scholar
  18. 18.
    Johnson DB, Nakada SY (2001) Cryosurgery and needle ablation of renal lesions. J Endourol 15:361–368PubMedCrossRefGoogle Scholar
  19. 19.
    Mitka M (2002) Tumoricidal temperature-related treatments. JAMA 287:440–441PubMedCrossRefGoogle Scholar
  20. 20.
    Lister J, Hoffman BF (1964) Reversible cold block of the specialized conduction tissues of the anaesthesized dog. Science 145:723–725PubMedCrossRefGoogle Scholar
  21. 21.
    Gallagher JJ, Sealy WC, Anderson RW et al (1977) Cryosurgical ablation of accessory atrioventricular connections: a method for correction of the pre-excitation syndrome. Circulation 55:471–479PubMedGoogle Scholar
  22. 22.
    Harrison L, Gallagher JJ, Kasell J et al (1977) Cryosurgical ablation of the A-V node-His bundle: a new method for producing A-V block. Circulation 55:463–470PubMedGoogle Scholar
  23. 23.
    Dubuc M, Roy D, Thibault B et al (1999) Transvenous catheter ice mapping and cryoablation of the atrioventricular node in dogs. Pacing Clin Electrophysiol 22:1488–1498PubMedCrossRefGoogle Scholar
  24. 24.
    Rodriguez LM, Leunissen J, Hoekstra A et al (1998) Transvenous cold mapping and cryoablation of the AV node in dogs: observations of chronic lesions and comparison to those obtained using radiofrequency ablation. J Cardiovasc Electrophysiol 9:1055–1061PubMedCrossRefGoogle Scholar
  25. 25.
    Pappone C, Vicedomini G, Manguso F et al (2006) Robotic magnetic navigation for atrial fibrillation ablation. J Am Coll Cardiol 47:1390–1400PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 2007

Authors and Affiliations

  • Andrea Colella
    • 1
  • Marzia Giaccardi
    • 2
    • 3
  • Luigi Padeletti
    • 1
  • Gian Franco Gensini
    • 1
  1. 1.Heart and Vessels DepartmentAzienda Ospedaliera Universitaria CareggiFlorence
  2. 2.Pediatric CardiologyAzienda A. MeyerFlorence
  3. 3.Don Gnocchi FoundationFlorenceItaly

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