Abstract
Since the initial description of the use of a transvenous endocardial lead for pacing in humans, in 1959 [1], the right ventricular apex (RVA) has served as the traditional site for lead positioning. However, RVA pacing produces an abnormal pattern of ventricular depolarization and there is growing evidence that pacing from this site is associated with adverse functional and structural changes in the left ventricle. This is manifested clinically in the deterioration of left ventricular (LV) function and increased morbidity and mortality. The results of numerous studies have described these observations, which were summarized in a recent review [2].
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Ovsyshcher, I.E. (2007). The Ideal Pacemaker for Complete AV Block. In: Gulizia, M.M. (eds) Current News in Cardiology. Springer, Milano. https://doi.org/10.1007/978-88-470-0636-2_40
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DOI: https://doi.org/10.1007/978-88-470-0636-2_40
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-0635-5
Online ISBN: 978-88-470-0636-2
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