Principles of Therapy of Infantile Hemangiomas and Other Congenital Vascular Tumors of the Newborns and Infants

  • Hans Peter Berlien


As hemangiomas frequently involute spontaneously, a wait-and-see principle is common. However, some cases need early treatment: these include “dangerous hemangiomas” of the face, anogenital region and rapidly growing hemangiomas. The goal of treatment should be to stop proliferation, speed up regression of large hemangiomas and prevent functional problems. The most common treatments are drug therapy, laser treatment, and surgical excision. Treatments such as X-ray and sclerotherapy are no longer indicated, and cryotherapy has been replaced by laser, while embolization is only indicated as a final treatment option.


Laser Therapy Vascular Malformation Vascular Tumor Spontaneous Regression Adjuvant Systemic Therapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Stevens M (2005) Solide Tumore bei Kindern. Annales Nestle 63:127–139Google Scholar
  2. 2.
    Poetke M, Berlien H-P (2005) Angeborne Gefäßanomalien. In: Pschyrembel Handbuch Therapie 3. Auflage S, pp 327–329Google Scholar
  3. 3.
    Scholz A, Sebastian G, Baerthold W et al (1980) Ergebnisse der Kryochirurgie bei der Behandlung benigner vaskulärer Fehl-und Neubildungen. Arch Geschwulstforsch 50:785–793PubMedGoogle Scholar
  4. 4.
    Li ZP (1992) Therapeutic coagulation induced in cavernous hemangioma by use of percutaneous copper needles. Plast Reconstr Surg 89:613–622CrossRefPubMedGoogle Scholar
  5. 5.
    Brevière GM, Bonnevalle M, Pruvo JP et al (1993) Use of ethibloc in the treatment of cystic and venous angiomas in children. 19 Cases. Eur J Ped Surg 3:166–170CrossRefGoogle Scholar
  6. 6.
    Tonner PH, Scholz J (1994) Mögliche Lungenembolie nach Embolisation eines Hämangioms mit Fibrinkleber. Anaesthesist 43:614–617CrossRefPubMedGoogle Scholar
  7. 7.
    Demuth RJ, Miller SH, Keller F (1984) Complications of embolization treatment for problem cavernous hemangiomas. Ann Plast Surg 13:135CrossRefPubMedGoogle Scholar
  8. 8.
    Winter H (1996) 20jährige Erfahrungen mit der Sklerosierungstherapie von Hämangiomen. Zbl Haut 168:7Google Scholar
  9. 9.
    Kushner BJ, Lemke BN (1993) Bilateral retinal embolization associated with intralesional corticosteroid injection for capillary hemangioma of infancy [letter; comment]. J Pediatr Ophthalmol Strabismus 30:397–399PubMedGoogle Scholar
  10. 10.
    Elsas FJ, Lewis AR (1994) Topical treatment of periocular capillary hemangioma. J Pediatr Ophthalmol Strabismus 31:153–156PubMedGoogle Scholar
  11. 11.
    Mazzuccioni MG (2007) Therapy with high-dose Dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic Thrombocytopenic Purpura — a GIMEMA experience. Blood 109:1401–1407CrossRefGoogle Scholar
  12. 12.
    Chowdri NA, Darzi MA, Fazili Z, Iqbal S (1994) Intralesional corticosteroid therapy for childhood cutaneous hemangiomas. Ann Plast Surg 33:46–51CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia 2009

Authors and Affiliations

  • Hans Peter Berlien
    • 1
  1. 1.Department of LasermedicineElisabeth KlinikBerlinGermany

Personalised recommendations