A small but significant percentage of hemangiomas develop at an extracutaneous location. The location has important prognostic and therapeutic implications. These hemangiomas are difficult to detect on physical examination and imaging studies are required in order to assess both size and behavior. An extracutaneous hemangioma is more serious than a cutaneous one. When detected in an infant, immediate intervention is required. In this chapter we describe the unique characteristics of central nervous system hemangiomas (that occur on the surface of the brain and spinal cord), parotid gland hemangiomas (in which the high overall response rate to pharmacological treatment does not exclude surgical treatment), thoracic hemangiomas (emphasizing the difficult differential diagnosis of intramuscular and congenital heart hemangiomas), and abdominal hemangiomas (with special focus on the management of focal, multicentric and diffuse liver hemangiomas — formerly known as hemangioendotheliomas — as well as the less common group of intestinal or genito-urinary hemangiomas).
KeywordsVenous Malformation Infantile Hemangioma Hepatic Hemangioma Spastic Diplegia Liver Hemangioma
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Haggstrom AN, Drolet BA, Baselga E et al (2006) Prospective study of infantile hemangiomas: clinical characteristics predicting complications and treatment. Pediatrics 118(3):882–887CrossRefPubMedGoogle Scholar
Frieden IJ, Haggstrom AN, Drolet BA et al (2005) Infantile hemangiomas: current knowledge, future directions. Proceedings of a research workshop on infantile hemangiomas. Pediatr Dermatol 22(5):383–406CrossRefPubMedGoogle Scholar
Poindexter G, Metry DW, Barkovich AJ, Frieden IJ (2007) PHACE syndrome with intracerebral hemangiomas, heterotopia, and endocrine dysfunction. Pediatr Neurol 36(6):402–406CrossRefPubMedGoogle Scholar
Scheunemann H (1975) Conservative parotidectomy in infancy and childhood. J Maxillofac Surg 3:37–40CrossRefPubMedGoogle Scholar
Greene AK, Rogers GF, Mulliken JB (2005) Management of parotid hemangioma. Plast Reconstr Surg 116(2):676–677CrossRefPubMedGoogle Scholar
Mackie AS, Kozakewich HP, Geva T et al (2005) Vascular tumors of the heart in infants and children: case series and review of the literature. Pediatr Cardiol 26(4):344–349CrossRefPubMedGoogle Scholar
Fishman SJ, Fox VL (2001) Visceral vascular anomalies. Gastrointest Endosc Clin N Am 11(4):813–834PubMedGoogle Scholar
Fishman SJ, Burrows PE, Leichtner AM, Mulliken JB (1998) Gastrointestinal manifestations of vascular anomalies in childhood: varied etiologies require multiple therapeutic modalities. J Pediatr Surg 33(7):1163–1167CrossRefPubMedGoogle Scholar
Christison-Lagay ER, Burrows PE, Alomari A et al (2007) Hepatic hemangiomas: subtype classification and development of a clinical practice algorithm and registry. J Pediatr Surg 42:62–67CrossRefPubMedGoogle Scholar
Blei F, Orlow SJ, Geronemus R (1997) Multimodal management of diffuse neonatal hemangiomatosis. J Am Acad Dermatol 37(6):1019–1021PubMedGoogle Scholar
Enjolras O, Riche MC, Merland JJ, Escande JP (1990) Management of alarming hemangiomas in infancy: a review of 25 cases. Pediatrics 85(4):491–498PubMedGoogle Scholar
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