An Update on Therapeutics: The Cancer Anorexia/Weight Loss Syndrome in Advanced Cancer Patients
Experienced oncologists acknowledge that the cancer anorexia/weight loss syndrome predicts a shorter survival for patients with advanced, incurable disease. Several powerful, well-conducted studies have borne out this clinical impression. DeWys et al. focused on weight loss in a multiinstitutional, retrospective review of 3047 cancer patients and observed that loss of more than 5% of premorbid weight predicted an early demise . This prognostic effect occurred independently of tumour stage, tumour histology and patient performance status. Weight loss was also associated with a trend towards lower chemotherapy response rates.
KeywordsClin Oncol Creatine Supplementation Anabolic Androgenic Steroid Advanced Cancer Patient North Central Cancer Treatment Group
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