An Update on Therapeutics: The Cancer Anorexia/Weight Loss Syndrome in Advanced Cancer Patients

  • Aminah Jatoi
  • Karin F. Giordano
  • Phuong L. Nguyen


Experienced oncologists acknowledge that the cancer anorexia/weight loss syndrome predicts a shorter survival for patients with advanced, incurable disease. Several powerful, well-conducted studies have borne out this clinical impression. DeWys et al. focused on weight loss in a multiinstitutional, retrospective review of 3047 cancer patients and observed that loss of more than 5% of premorbid weight predicted an early demise [1]. This prognostic effect occurred independently of tumour stage, tumour histology and patient performance status. Weight loss was also associated with a trend towards lower chemotherapy response rates.


Clin Oncol Creatine Supplementation Anabolic Androgenic Steroid Advanced Cancer Patient North Central Cancer Treatment Group 
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Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • Aminah Jatoi
    • 1
  • Karin F. Giordano
    • 1
  • Phuong L. Nguyen
    • 2
  1. 1.Department of OncologyMayo ClinicRochesterUSA
  2. 2.Department of Laboratory Medicine and PathologyMayo ClinicRochesterUSA

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