A Critical Assessment of the Outcome Measures and Goals of Intervention in Cancer Cachexia

  • Kenneth C. H. Fearon
  • Richard J. E. Skipwoth


Cancer cachexia is a multifactorial, multifaceted problem for which there is no uniform pathophysiological or clinical definition [1]. It is generally accepted as a complex syndrome with several cardinal features, including anorexia, early satiety, severe weight loss, muscle wasting, ischaemia, anaemia and oedema [2]. The essential characteristic that distinguishes cachexia from simple starvation is that the features of cachexia cannot be readily reversed by nutritional support alone [3].


Total Energy Expenditure Cancer Cachexia Reduce Food Intake Rest Energy Expenditure Cachexia Syndrome 
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Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • Kenneth C. H. Fearon
    • 1
  • Richard J. E. Skipwoth
    • 1
  1. 1.Department of Clinical and Surgical Sciences (Surgery)The University of EdinburghRoyal InfirmaryUK

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