Dietary Intake, Resting Energy Expenditure, Weight Loss, and Survival in Cancer Patients

  • Kent Lundholm
  • Ingvar Bosaeus


Weight loss is frequently seen in patients with advanced cancer and has long been recognised to be associated with decreased survival [1]. Cancer cachexia is a complex syndrome depending on cytokines, eicosanoids, and classical hormones, and characterised by progressive weight loss with depletion of host reserves of skeletal muscle and adipose tissue. It is the net result of profound metabolic changes that appear in patients with advanced stages of cancer, and is characterised by net breakdown of skeletal muscle and alterations in fat and carbohydrate metabolism. Cachexia is the most common paraneoplastic syndrome, and is also referred to as the cancer anorexia-cachexia syndrome, with features of anorexia, early satiety, weakness, and fatigue.


Energy Intake Lung Cancer Patient Total Energy Expenditure Cancer Cachexia Rest Energy Expenditure 
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Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • Kent Lundholm
    • 1
  • Ingvar Bosaeus
    • 2
  1. 1.Department of SurgeryGöteborg University, Sahlgrenska University HospitalGöteborgSweden
  2. 2.Clinical Nutrition, Göteborg University, Sahlgrenska University HospitalGöteborgSweden

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