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Dietary Intake, Resting Energy Expenditure, Weight Loss, and Survival in Cancer Patients

  • Chapter
Cachexia and Wasting: A Modern Approach

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Abstract

Weight loss is frequently seen in patients with advanced cancer and has long been recognised to be associated with decreased survival [1]. Cancer cachexia is a complex syndrome depending on cytokines, eicosanoids, and classical hormones, and characterised by progressive weight loss with depletion of host reserves of skeletal muscle and adipose tissue. It is the net result of profound metabolic changes that appear in patients with advanced stages of cancer, and is characterised by net breakdown of skeletal muscle and alterations in fat and carbohydrate metabolism. Cachexia is the most common paraneoplastic syndrome, and is also referred to as the cancer anorexia-cachexia syndrome, with features of anorexia, early satiety, weakness, and fatigue.

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Author information

Authors and Affiliations

  1. Department of Surgery, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden

    Kent Lundholm

  2. Clinical Nutrition, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden

    Ingvar Bosaeus

Authors
  1. Kent Lundholm
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  2. Ingvar Bosaeus
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Editor information

Editors and Affiliations

  1. Department of Medical Oncology, University of Cagliari, Cagliari, Italy

    Giovanni Mantovani

  2. Department of Clinical Cardiology, Imperial College, NHLI, London, UK

    Stefan D. Anker

  3. Department of Cardiology Charité, Applied Cachexia Research, Campus Virchow-Klinikum, Berlin, Germany

    Stefan D. Anker

  4. Department of Behavioral Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

    Akio Inui

  5. GRECC, VA Medical Center and Division of Geriatric Medicine, Saint Louis University, St. Louis, MO, USA

    John E. Morley

  6. Department of Clinical Medicine, University of Rome, La Sapienza, Rome, Italy

    Filippo Rossi Fanelli

  7. Department of Infectious Diseases, IRCCS S.Matteo Polyclinic, University of Pavia, Pavia, Italy

    Daniele Scevola

  8. Bone Marrow and Blood Stem Cell Transplantation Program, Center for Lymphoma and Myeloma, New York Presbyterian Hospital/Weill Medical Center, New York, NY, USA

    Michael W. Schuster

  9. Department of Medicine-Geriatrics, University of New York at Stony Brook VAMC, Northport, NY, USA

    Shing-Shing Yeh

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© 2006 Springer-Verlag Italia

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Lundholm, K., Bosaeus, I. (2006). Dietary Intake, Resting Energy Expenditure, Weight Loss, and Survival in Cancer Patients. In: Mantovani, G., et al. Cachexia and Wasting: A Modern Approach. Springer, Milano. https://doi.org/10.1007/978-88-470-0552-5_47

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  • DOI: https://doi.org/10.1007/978-88-470-0552-5_47

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0471-9

  • Online ISBN: 978-88-470-0552-5

  • eBook Packages: MedicineMedicine (R0)

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