Lipid Mobilising Factor in Cancer Cachexi

  • Alessandro Laviano
  • Maurizio Muscaritoli
  • Filippo Rossi Fanelli


During disease, a formidable biological fight occurs between invading cells and the defending host.As a consequence, both sides use all the available weapons to succeed: invaders will try to shut off the host defence systems while the host will try to isolate and destroy the invaders. Metabolic perturbations inevitably develop and, if the challenge is prolonged over time, changes in body composition occur. Thus, cachexia could be considered as ‘collateral damage’ in the fight between invading cells and the defending host.


Adenylate Cyclase Brown Adipose Tissue Cancer Cachexia Rest Energy Expenditure Interscapular Brown Adipose Tissue 
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Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • Alessandro Laviano
    • 1
  • Maurizio Muscaritoli
    • 1
  • Filippo Rossi Fanelli
    • 1
  1. 1.Department of Clinical MedicineUniversity of Rome La SapienzaRomeItaly

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