Psychiatric Diseases and Depression

  • Adelio Lucca
  • Enrico Smeraldi


Changes in appetite and weight loss are commonly occurring symptoms in various psychiatric diseases; however, it is clear that a disturbance of appetite is a cardinal feature of depressive disorders. There is a large amount of data available about the epidemiology, phenomenology, associated neurobiological findings, and pharmacological interventions that bear on the links between mood disorders and appetite. The findings may ultimately contribute to our understanding of appetite regulation per se.


Anorexia Nervosa Eating Disorder Hamilton Depression Rating Scale Late Life Depression Appetite Regulation 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Ivarsson T, Rastam M, Wentz E et al (2000) Depressive disorders in teenage-onset anorexia nervosa: a controlled longitudinal, partly-community-based study. Compr Psychiatry 41:398–403PubMedCrossRefGoogle Scholar
  2. 2.
    Cooper Z (1995) The development and maintenance of eating disorders. In: Brownell KD, Fairburn CG (ed) Eating disorders and obesity. The Guilford Press, New York,pp 199–206Google Scholar
  3. 3.
    Tiemeier H (2003) Biological risk factors for late life depression. Eur J Epidemiol 18:745–750PubMedCrossRefGoogle Scholar
  4. 4.
    Koo JR, Yoon JW, Kim SG et al (2003) Association of depression with malnutrition in chronic hemodialysis patient. Am J Kidney Dis 41:1037–1042PubMedCrossRefGoogle Scholar
  5. 5.
    Wang PN, Yang CL, Lin KN et al (2004) Weight loss, nutritional status and physical activity in patients with Alzheimer’s Disease: a controlled study. J Neurol 251:314–320PubMedCrossRefGoogle Scholar
  6. 6.
    Anonymous (1994) American Psychiatric Association. Diagnostic and statistical manual of mental disorders, DSM-IV. American Psychiatric Association, Washington DCGoogle Scholar
  7. 7.
    Franke L, Schewe HJ, Uebelhack R et al (2003) Platelet-5HT uptake and gastrointestinal symptoms in patients suffering from major depression. Life Sci 74:521–531PubMedCrossRefGoogle Scholar
  8. 8.
    Gershon MD (1999) Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther 13(Suppl 2):15–30PubMedGoogle Scholar
  9. 9.
    Chen JJ, Li Z, Pan H et al (2001) Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: abnormal intestinal motility and the expression of cation transporters. J Neurosci 15:6348–6361Google Scholar
  10. 10.
    Morley JE, Miller DK, Perry HM 3rd et al (1999) Anorexia of aging, leptin, and the Mini Nutritional Assessment. Nestle Nutr Workshop Ser Clin Perform Programme 1:67–76PubMedGoogle Scholar
  11. 11.
    Dubas-Slemp H, Marmurowska-Michalowska H, Szuster-Ciesielska A et al (2003) The role of cytokines in depression. Psychiatr Pol 37:787–798PubMedGoogle Scholar
  12. 12.
    Gillette-Guyonnet S, Nourhashemi F, Andrieu S et al (2000) Weight loss in Alzheimer disease. Am J Clin Nutr 71:637S–642SPubMedGoogle Scholar
  13. 13.
    Berrios GE, Luque R (1995) Cotard’s syndrome: analysis of 100 cases. Acta Psychiatr Scand 91:185–188PubMedCrossRefGoogle Scholar
  14. 14.
    Anonymous (1993) World Health Organization. ICD-10 classification of mental and behavioural disorders: diagnostic criteria for research. Geneva, SwitzerlandGoogle Scholar
  15. 15.
    Lyn P (2002) Eating disorders: a review of the literature with emphasis on medical complications and clinical nutrition. Altern Med Rev 7:184–202Google Scholar

Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • Adelio Lucca
    • 1
  • Enrico Smeraldi
    • 1
  1. 1.Psychiatric Clinic, San Raffaele HospitalMilanItaly

Personalised recommendations