Starvation: Social, Voluntary, and Involuntary Causes of Weight Loss

  • Daniele Scevola
  • Angela Di Matteo
  • Omar Giglio
  • Filippo Uberti


Under physiological conditions, body weight remains remarkably stable because of the importance of maintaining energy stores. A complex network of neural and hormonal factors regulates appetite and metabolism. A fundamental role is played by hypothalamic centres of feeding and satiety. Neuropeptides induce anorexia by acting on the satiety centre; gastrointestinal peptides, such as glucagon, somatostatin, and cholecystokinin, induce anorexia by vagal signalling; hypoglycaemia inhibits satiety centre. Leptin, produced by adipose tissue, acts on the hypothalamus to decrease food intake and increase energy expenditure, thus achieving long-term weight homoeostasis [1].


Gross Domestic Product Food Insecurity Decrease Food Intake Body Mass Index Score Food Balance Sheet 
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Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • Daniele Scevola
    • 1
  • Angela Di Matteo
    • 2
  • Omar Giglio
    • 2
  • Filippo Uberti
    • 1
  1. 1.Department of Infectious Diseases, IRCCS S.Matteo PolyclinicUniversity of PaviaPaviaItaly
  2. 2.Department of Infectious DiseasesUniversity of Pavia, IRCCS Policlinico S.MatteoPaviaItaly

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