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Structure, synthesis and characterization of contrast agents for magnetic resonance molecular imaging

  • Sophie Laurent
  • Luce Vander Elst
  • Alain Roch
  • Robert N. Muller

Abstract

Magnetic resonance imaging (MRI) is a non invasive method that, in a medical context, allows the identification and characterization of pathological tissues and lesions. The principle of this technique is based on the application of magnetic field gradients in three dimensions. The image results from the spatial identification of hydrogen nuclei. This image is constituted of elements, “pixels”, where grey levels represent the signal intensity emitted by corresponding volume elements, “voxels”. As the signal depends on the concentration in protons and on nuclear relaxation times, T1 and T2, modulations of image intensity are observed.

Keywords

Contrast Agent Relaxation Rate Paramagnetic Center Anisotropy Energy Outer Sphere 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2007

Authors and Affiliations

  • Sophie Laurent
    • 1
  • Luce Vander Elst
    • 1
  • Alain Roch
    • 1
  • Robert N. Muller
    • 1
  1. 1.Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging LaboratoryUniversity of Mons-HainautMonsBelgium

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