Estratto
In seguito alla provocazione con vari stimoli, i bronchi possono rispondere con una ostruzione delle vie aeree. Gli stimoli possono essere specifici o non specifici. Gli stimoli che inducono una risposta immonologica, quale la risposta IgE-mediata evocata dagli allergeni (atopia), sono definiti “stimoli specifici”. Fra questi sono state individuate diverse sostanze con proprietà antigeniche, caratteristiche dell’asma atopico: polveri di casa, peli e forfora di animali (cane gatto, coniglio, ecc.), pollini di piante (graminacee, alberi, ecc.) e spore di muffe.
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Letture consigliate
American Thoracic Society (1991) Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 144:1202–1218
American Thoracic Society (2000) Guidelines for methacholine and exercise challenge testing. Am J Respir Crit Care Med Vol 161; pp 309–329
Beach JR, Young CL, Avery AJ et al (1993) Measurement of airway responsiveness to methacholine: relative importance of the precision of drug delivery and the method of assessing response. Thorax 48:239–243
Becklake MR, Toyota B, Stewart M et al (1983) Lung structure as a risk factor in adverse pulmonary responses to asbestos exposure. Am Rev Respir Dis 128:385–388
Braman SS, Barrows AA, De Cottis BA et al (1987) Airway responsiveness in allergic rhinitis: a risk factor for asthma. Chest 61:671–674
Burns GP, Gibson GJ (1998) Airway hyperresponsiveness in asthma: not just a problem of smooth muscle relaxation with inspiration. Am J Respir Crit Care Med 158:203–206
Chai HR, Farr S, Froehlich LA et al (1975) Standardization of bronchial inhalation challenge procedures. J Allergy Cl Immunol 56:323–327
Chatham M, Bleecker ER, Smith PL et al (1982) A comparison of histamine, methacholine, and exercise airway reactivity in normal and asthmatic subjects. Am Rev Respir Dis 126:235–240
Chatham M, Bleeker ER, Norman P et al (1982) A screening test for airways reactivity: an abbreviated methacholine inhalation challenge. Chest 82:15–18
Cockcroft DW, Berscheid BA, Murdock KY (1983) Measurement of responsiveness to inhaled histamine using FEV: comparison of PC-20 and threshold. Thorax 38:523–526
Cockcroft DW, Hargreave FE (1991) Airways hyperresponsiveness: definition, measurement and clinical relevance. In: Kaliner MA, Barnes PJ, Persson CGA (eds) Asthma: its pathology and treatment. Marcel Dekker, New York
Cockroft DW, Bersheid BA, Murdock KY (1983) Unimodal distribution of bronchial responsiveness to inhaled histamine in a random human population. Chest 83:751–754
Dales RE, Nunes F, Partyka D et al (1988) Clinical prediction of airways hyperresponsiveness. Chest 5:984–986
Dennis JH, Avery AJ, Walters EH et al (1992) Calibration of aerosol output from Mefar dosimeter implications for epidemiological studies. Eur Respir J 5:1279–1282
Dennis JH, Avery AJ, Walters EH et al (1992) Calibration of aerosol output from the Mefar dosimeter: implications for epidemiological studies. Eur Respir J 5:1279–1282
Dinh Xuan AT, Lockhart A (1991) Use of nonspecific bronchial challenges in the assessment of anti-asthmatic drugs. Eur Respir Rev 1:19–24
Ebina M, Takahashi T, Tamihiko C et al (1993) Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study. Am Rev Respir Dis 148:720–726
Eiser NM, Kerrebijn KF, Quanjer PH, (1983) Guidelines for standardization of bronchial challenges with (nonspecific) bronchcconstriction agents. Bull. Eur Physiopathol Respir 19:491–514
Ferron GA, Kerrebijn KF, Weber J (1976) Properties of aerosols produced with three nebulizers. Am Rev Respir Dir 114:899–908
Fish JE, Kelley JF (1979) Measurements of responsiveness in bronchoprovocation testing. J Allergy Clin Immunol 64:592–596
Fish JE, Rosenthal RR, Batra G et al (1976) Airway responses to methacholine in allergic and nonallergic subjects. Am Rev Respir Dis 113:579–586
Goldstein MF, Pacana SM, Dvorin DJ et al (1994) Retrospective’analyses of methacholine inhalation challenges. Chest 105:1082–1088
Greenspon LW, Gracely E (1992) A discriminant analysis applied to methacholine bronchoprovocation testing improves classification of patients as normal, asthma or COPD. Chest 102:1419–1425
Hayes RD, Beach JR, Rutherford DM et al (1998) Stability of methacholine chloride solutions under different storage conditions over a 9 month period. Eur Respir J 11:946–948
Hopp RJ, Townley RG, Biven RE et al (1990) The presence of airway reactivity before the development of asthma. Am Rev Respir Dis 141:2
Jongejan RC, De Jongste JC, Kerrebijn KF (1991) The increased responsiveness to inhaled methacholine in asthma: combination of causative factors. Am Rev Respir Dis 143:1194–1196
Juniper EF, Frith PA, Dunnett C et al (1995) Reproducibility and comparison of responses to inhaled histamine and methacholine. Thorax 33:705–710
Knox AJ, Wisniewski A, Cooper S et al (1991) A comparison of the Yan and a dosimeter method for methacholine challenge in experienced and inexperienced subjects. Eur Respir J 4:497–502
Kongerud J, Soyseth V, Johansen B (1989) Room temperature influences output from the Wright jet nebulizer. Eur Respir J 2:681–684
Laube BL., Norman PS, Adams GK (1992) The effect of aerosol distribution on airway responsiveness to inhaled methacholine in patients with asthma. J Allergy Clin Immunol 89:510–518
Loffert DT, Ikle D, Nelson HS (1994) A comparison of commercial jet nebulizers. Chest 106:1788–1792
MacDonald NC, Whitmore CK, Makoid MC (1981) Stability of methacholine chloride in bronchial provocation test solutions. Am J Hosp Pharmacy 381:868–871
Macklem PT (1996) A theoretical analysis of the effect of airway smooth muscle load on airway narrowing. Am J Respir Crit Care Med 153:83–89
Malmberg P, Larsson K, Sundblad BM et al (1993) Importance of the time interval between FEV1 measurements in a methacholine provocation test. Eur Respir J 6:680–686
Malmberg P, Larsson K, Sundblad BM et al (1993) Importance of the time interval between FEV, measurements in a methacholine provocation test. Eur Respir J 6:680–686
Martin TR, Castile RG, Fredberg JJ et al (1987) Airway size is related to sex but not lung size in normal adults. J Appl Physiol 63:2041–2047
Martinez FD, Morgan WJ, Wright AL et al (1991) Initial airway function is a risk factor for recurrent wheezing respiratory illnesses during the first three years of life. Am Rev Respir Dis 143:312–316
Moore BJ, Vergurgt LM, King GG et al (1997) The effect of deep aspiration on methacholine dose-response curves in normal subjects. Am J Respir Crit Care Med 156:1270–1281
Moreno RH, Hogg JC, Paré PD (1985) Mechanics of airway narrowing. Am Rev Respir Dis 133:1171–1180
Moreno RH, Hogg JC, Pare PD (1986) Mechanics of airway narrowing. Am Rev Respir Dis 133:1171–1180
Nadel JA, Tierney DF (1961) Effect of a previous deep inspiration on airway resistance in man. J Appl Physiol 16:717–719
Nieminen MM, Holli H, Lahdensuo A et al (1987) Aerosol deposition in automatic dosimeter nebulizer. Eur J Respir Dis 71:145–152
O’Byrne PM, (1986) Airway inflammation and airway hyperresponsiveness. Chest 90:575–577
O’Connor G, Sparrow D, Taylor D et al (1987) Analysis of dose-response curves to methacholine: an approach suitable for population studies. Am Rev Respir Dis 136:1412–1417
Parham JW, Shepard RH, Norman PS et al (1983) Analysis of time course and magnitude of lung inflation effects on airway tone: relation to airway reactivity. Am Rev Respir Dis 128:240–245
Parker CD, Bilbo RE, Reed CE (1965) Methacholine aerosol as test for bronchial asthma. Arch Intern Med 115:452–458
Postma DS, Kerstjens HA (1998) Characteristics of airway hyperresponsiveness in asthma and chronic obstructive pulmonary disease. Am J Respir Crit Cure Med 58[Suppl]:S187–S192
Pratter MR, Woodman TF, Irwin RS et al (1982) Stability of stored methacholine chloride solutions: clinically useful information. Am Rev Respir Dis 126:717–719
Prieto JL, Gutierrez V, Berto JM et al (1996) Sensitivity and maximal response to methacholine in perennial and seasonal allergic rhinitis. Clin Exp Allergy 26:6167
Quanjer PH, Tammeling GJ, Cotes JE et al (1993) Lung volumes and forced ventilatory flows. Report of working party. Standardization of lung function tests. European Community for Steel and Coal. Official statement of the European Respiratory Society. EurRespir J 6[Suppl 16]:5–40
Rosenthal RR (1989) Approved methodology for methacholine challenge. Allergy Proc 10:301–310
Ruffin RE, Dolovich MB, Wolffe RK et al (1978) The effects of preferential deposition of histamine in the human airway. Am Rev Respir Dis 117:485–492
Ryan G, Dolovich MB, Obminski G et al (1981) Standardization of inhalation provocation tests: influence of nebulizer output, particle size, and method of inhalation. J Allergy Clin Immunol 67:156–161
Ryan G, Dolovich MB, Roberts RS et al (1981) Standardization of inhalation provocation tests: two techniques of aerosol generation and inhalation compared. Am Rev Respir Dis 123:195–199
Shapiro GG, Simon RA (1992) Bronchoprovocation committee report. J Allergy Clin Immunol 89:775–778
Shen X, Wu MF, Tepper RS et al (1997) Mechanisms for the mechanical response of airway smooth muscle to length oscillations. J Appl Physiol 83:731–738
Sherman CB, Kern DG, Corwin RW et al (1994) A clinical and structural comparison of industrial methacholine and Provocholine. Chest 105:1095–1097
Skloot G, Permutt S, Togias A (1995) Airway responsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration. J Clin Invest 96:2393–2403
Skloot G, Permutt S, Togias AG (1995) Airway hyperresponsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration. J Clin Invest 96:2393–2403
Smith L, McFadden ER (1995) Bronchial hyperreactivity revisited. Ann Allergy Asthma Immunol 74:454–469
Solway J, Fredberg JJ (1997) Perhaps airway smooth muscle dysfunction contributes to asthmatic bronchial hyperresponsiveness after all. Am J Respir Cell Mol Biol 17:144–146
Sparrow D, O’Connor G, Colton T et al (1987) The relationship of nonspecific bronchial responsiveness to the occurrence of respiratory symptoms and decreased levels of pulmonary function: the Normative Aging Study. Am Rev Respir Dis 135:1255–1260
Sparrow D, O’Connor GT, Basner RC et al (1993) Predictors of the new onset of wheezing among middle-aged and older men: the Normative Aging Study. Am Rev Respir Dis 147:367–371
Sterk PJ, Fabbri LM, Quanjer PH et al (1993) Airway responsiveness: standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Statement of the European Respiratory Society Eur Respir J 6[Suppl 16]:53–73
Sterk PJ, Plomp A, van de Vate JF et al (1984) Physical properties of aerosols produced by several jet and ultrasonic nebulizers. Bull Eur Physiopathol Respir 20:65–72
Terzano C, Laurendi G, Capoccetta G et al (2003) The smooth muscle and airway hyperresponsiveness. Eur Rev Med Pharmacol Sci 7(1):9–26
Ward RJ, Reid DW, Walters EH (1997) Variation in nebuliser output and weight output from the Mefar dosimeter. Implications for multicentre studies. Eur Respir J 10:2436–2437
Watson BL, Cormier RA., Harbeck RJ (1998) Effect of pH on the stability of methacholine chloride in solution. Respir Med 921:588–592
Weiss ST, Tager IB., Weiss JW et al (1984) Airways responsiveness in a population sample of adults and children. Am Rev Respir Dis 129:898–902
Wheatley JR, Pare PD, Engel LA (1989) Reversibility of induced bronchoconstriction by deep inspiration in asthmatics and normal subjects. Eur Respir J 2:331–339
Wiggs BR, Bosken C, Pare PD et al (1992) A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 145:1251–1258
Woolcock AJ, Peat JK, Salome CM et al (1987) Prevalence of bronchial hyperresponsiveness and asthma in a rural adult population. Thorax 42:361–368
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Terzano, C. (2006). Test di iperresponsività bronchiale. In: Malattie dell’apparato respiratorio. Springer, Milano. https://doi.org/10.1007/978-88-470-0467-2_6
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