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Anxiety and Heart Disease

  • D. K. Moser
  • M. J. De Jong

Abstract

Despite impressive gains made in the treatment of coronary heart disease (CHD), it remains the number one cause of death and a major cause of disability among women and men in the United States (US). By the year 2020, CHD is projected to be the number one cause of death worldwide [1]–[3]. Coronary heart disease claims more lives each year than the next five causes of death combined [1]. The effect of various demographic (e.g., age, gender) and clinical (e.g., the presence of comorbidities) characteristics on development of cardiac events and on recovery has been well studied [4]. These demographic and clinical characteristics are used commonly in clinical practice to determine patient risk for future events.

Keywords

Acute Myocardial Infarction Anxiety Level Mental Stress High Anxiety Coronary Heart Disease Event 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    American Heart Association (2002) Heart disease and stroke statistics-2003 update. Dallas: American Heart AssociationGoogle Scholar
  2. 2.
    Chockalingam A, Balaguer-Vintro I, Achutti A et al (2000) The World Heart Federation’s white book: impending global pandemic of cardiovascular diseases: challenges and opportunities for the prevention and control of cardiovascular diseases in developing countries and economies in transition. Canad J Cardiol 16:227–229Google Scholar
  3. 3.
    Reddy KS, Yusuf S (1998) Emerging epidemic of cardiovascular disease in developing countries. Circulation 97:596–601PubMedGoogle Scholar
  4. 4.
    Breithardt G, Borggrefe M, Fetsch T et al (1995) Prognosis and risk stratification after myocardial infarction. Eur Heart J 16(Suppl G):10–19PubMedGoogle Scholar
  5. 5.
    Kubzansky LD, Kawachi I (2000) Going to the heart of the matter: do negative emotions cause coronary heart disease? J Psychosom Res 48:323–337PubMedGoogle Scholar
  6. 6.
    Kubzansky LD, Kawachi I, Weiss ST, Sparrow D (1998) Anxiety and coronary heart disease: a synthesis of epidemiological, psychological, and experimental evidence. Ann Behav Med 20:47–58PubMedGoogle Scholar
  7. 7.
    Rozanski A, Blumenthal JA, Kaplan J (1999) Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation 99:2192–2217PubMedGoogle Scholar
  8. 8.
    Barlow DH (1988) Anxiety and its disorders. New York: GuilfordGoogle Scholar
  9. 9.
    Lewis MA, Haviland JM (Eds) (1993) Fear and anxiety as emotional phenomena: Clinical phenomenology, evolutionary perspectives, and information-processing mechanisms. New York: Guilford PressGoogle Scholar
  10. 10.
    Smith TW, Ruiz JM (2002) Psychosocial influences on the development and course of coronary heart disease: current status and implications for research and practice. J Consult Clin Psychol 70:548–568PubMedGoogle Scholar
  11. 11.
    Kubzansky LD, Kawachi I, Spiro A et al (1997) Is worrying bad for your heart? A prospective study of worry and coronary heart disease in the Normative Aging Study. Circulation 95:818–824PubMedGoogle Scholar
  12. 12.
    Crowe JM, Runions J, Ebbesen LS et al (1996) Anxiety and depression after acute myocardial infarction. Heart and Lung 25:98–107PubMedGoogle Scholar
  13. 13.
    Januzzi JL, Jr. Stern TA, Pasternak RC, DeSanctis RW (2000) The influence of anxiety and depression on outcomes of patients with coronary artery disease. Arch Intern Med 160:1913–1921PubMedGoogle Scholar
  14. 14.
    Malan SS (1992) Psychosocial adjustment following MI: current views and nursing implications. J Cardiovascul Nurs 6:57–70Google Scholar
  15. 15.
    Moser DK, Dracup K (1996) Is anxiety early after myocardial infarction associated with subsequent ischemic and arrhythmic events? Psychosom Med 58:395–401PubMedGoogle Scholar
  16. 16.
    Moser DK, McKinley S, Riegel B et al (2002) Perceived control reduces in-hospital complications associated with anxiety in acute myocardial infarction (abstract) Circulation 106:II-369Google Scholar
  17. 17.
    Sirois BC, Burg MM (2003) Negative emotion and coronary heart disease. A review. Behav Mod 27:83–102Google Scholar
  18. 18.
    Mayou RA, Gill D, Thompson DR et al (2000) Depression and anxiety as predictors of outcome after myocardial infarction. Psychosom Med 62:212–219PubMedGoogle Scholar
  19. 19.
    Moser DK, Dracup K (1995) Psychosocial recovery from a cardiac event: the influence of perceived control. Heart and Lung 24:273–280PubMedGoogle Scholar
  20. 20.
    Rozanski A, Bairey CN, Krantz DS et al (1988) Mental stress and the induction of silent myocardial ischemia in patients with coronary artery disease. N Eng J Med 318:1005–1012Google Scholar
  21. 21.
    Rozanski A, Krantz DS, Bairey CN (1991) Ventricular responses to mental stress testing in patients with coronary artery disease. Pathophysiological implications. Circulation 83(4 Suppl):II-137–144Google Scholar
  22. 22.
    Lane D, Carroll D, Ring C et al (2000) Do depression and anxiety predict recurrent coronary events 12 months after myocardial infarction? QJM 93:739–744PubMedGoogle Scholar
  23. 23.
    Lane D, Carroll D, Ring C et al (2000) Effects of depression and anxiety on mortality and quality-of-life 4 months after myocardial infarction. J Psychosom Res 49:229–238PubMedGoogle Scholar
  24. 24.
    Lane D, Carroll D, Ring C et al (2001) Mortality and quality of life 12 months after myocardial infarction: effects of depression and anxiety. Psychosom Med 63:221–230PubMedGoogle Scholar
  25. 25.
    Mayou R (2000) Research as a basis for clinical care. J Psychosom Res 48:321–322PubMedGoogle Scholar
  26. 26.
    Maeland JG, Havik OE (1989) After the myocardial infarction. A medical and psychological study with special emphasis on perceived illness. Scand J Rehabil Med Suppl 22:1–87PubMedGoogle Scholar
  27. 27.
    Rose SK, Conn VS, Rodeman BJ (1994) Anxiety and self-care following myocardial infarction. Issues in Mental Health Nursing 15:433–444PubMedGoogle Scholar
  28. 28.
    Sullivan MD, LaCroix AZ, Baum C et al (1997) Functional status in coronary artery disease: a one-year prospective study of the role of anxiety and depression. Am J Med 103:348–356PubMedGoogle Scholar
  29. 29.
    Sullivan MD, LaCroix AZ, Spertus J A, Hecht J (2000) Five-year prospective study of the effects of anxiety and depression in patients with coronary artery disease. Ame J Cardiol 86:1135–1138Google Scholar
  30. 30.
    Havik OE, Maeland JG (1990) Patterns of emotional reactions after a myocardial infarction. J Psychosom Res 34:271–285PubMedGoogle Scholar
  31. 31.
    Rosal MC, Downing J, Littman AB, Ahern DK (1994) Sexual functioning post-myocardial infarction: effects of beta-blockers, psychological status and safety information. J Psychosom Res 38:655–667PubMedGoogle Scholar
  32. 32.
    Sykes DH, Evans AE, Boyle DM et al (1989) Discharge from a coronary care unit: psychological factors. J Psychosom Res 33:477–488PubMedGoogle Scholar
  33. 33.
    Denollet J, Brutsaert DL (1998) Personality, disease severity, and the risk of longterm cardiac events in patients with a decreased ejection fraction after myocardial infarction. Circulation 97:167–173PubMedGoogle Scholar
  34. 34.
    Frasure-Smith N, Lesperance F, Talajic M (1995) The impact of negative emotions on prognosis following myocardial infarction: is it more than depression? Health Psychol 14:388–398PubMedGoogle Scholar
  35. 35.
    Thomas SA, Friedmann E, Wimbush F, Schron E (1997) Psychological factors and survival in the cardiac arrhythmia suppression trial (CAST): a re-examination. Am J Crit Care 6:116–126PubMedGoogle Scholar
  36. 36.
    Lin KM (2001) Biological differences in depression and anxiety across races and ethnic groups. J Clinic Psychiat 62(Suppl 13):13–19Google Scholar
  37. 37.
    Lepine JP (2001) Epidemiology, burden, and disability in depression and anxiety. J Clinic Psychiat 62(Suppl 13):4–10Google Scholar
  38. 38.
    Kirmayer LJ (2001) Cultural variations in the clinical presentation of depression and anxiety: implications for diagnosis and treatment. J Clinic Psychiat 62(Suppl 13):22–28Google Scholar
  39. 39.
    DeJong MI, Chung ML, Roser LP et al (2004) A five-country comparison of anxiety early after acute myocardial infarction. Europ J Cardiovas Nursing 3:129–134Google Scholar
  40. 40.
    Derogatis LR, Melisaratos N (1983) The Brief Symptom Inventory: an introductory report. Psychologic Med 13:595–605Google Scholar
  41. 41.
    Draguns JG, Tanaka-Matsumi J (2003) Assessment of psychopathology across and within cultures: issues and findings. Behav Res Ther 41:755–776PubMedGoogle Scholar
  42. 42.
    Taylor-Piliae RE, Molassiotis A (2001) An exploration of the relationships between uncertainty, psychological distress and type of coping strategy among Chinese men after cardiac catheterization. J Advan Nursing 33:79–88Google Scholar
  43. 43.
    Leff JP (1973) Culture and the differentiation of emotional states. Bri J Psychiat 123:299–306Google Scholar
  44. 44.
    Mesquita B, Frijda NH (1992) Cultural variations in emotions: a review. Psychologic Bull 112:179–204Google Scholar
  45. 45.
    Scherer KR, Wallbott HG, Matsumoto D, Kudoh T (1988) Emotional experience in cultural context: a comparison between Europe, Japan, and the United States. In K. R. Scherer (Ed) Facets of Emotion: Recent Research (pp 5–30) Hillsdale, New Jersey: Lawrence Erlbaum AssociatesGoogle Scholar
  46. 46.
    Chiou A, Potempa K, Buschmann MB (1997) Anxiety, depression and coping meth ods of hospitalized patients with myocardial infarction in Taiwan. Int J Nursing Stud 34:305–311Google Scholar
  47. 47.
    Lepine JP (2001) Epidemiology, burden, and disability in depression and anxiety. J Clin Psychiat 62(Suppl 13):4–10Google Scholar
  48. 48.
    Derogatis LP (1993) BSI. Brief Symptom Inventory. Administration, scoring, and procedure manual. Minneapolis: National Compute Systems, Inc.Google Scholar
  49. 49.
    Legault SE, Joffe RT, Armstrong PW (1992) Psychiatric morbidity during the early phase of coronary care for myocardial infarction: association with cardiac diagnosis and outcome. Can J Psychiat 37:316–325Google Scholar
  50. 50.
    Brown N, Melville M, Gray D et al (1999) Quality of life four years after acute myocardial infarction: short form 36 scores compared with a normal population. Heart 81:352–358PubMedGoogle Scholar
  51. 51.
    Moser DK, Dracup K, McKinley S et al (2003) An international perspective on gender differences in anxiety early after acute myocardial infarction. Psychosom Me 65:511–516Google Scholar
  52. 52.
    Martin RL, Cloninger CR, Guze SB, Clayton PJ (1985) Mortality in a follow-up of 500 psychiatric outpatients. I. Total mortality. Arch Gen Psychiat 42:47–54PubMedGoogle Scholar
  53. 53.
    Haines AP, Imeson JD, Meade TW (1987) Phobic anxiety and ischaemic heart disease. Bri Med J (Clinical Research Ed) 295:297–299Google Scholar
  54. 54.
    Weissman MM, Markowitz JS, Ouellette R et al (1990) Panic disorder and cardiovascular/cerebrovascular problems: results from a community survey. Am J Psychiat 147:1504–1508PubMedGoogle Scholar
  55. 55.
    Eaker ED, Pinsky J, Castelli WP (1992) Myocardial infarction and coronary death among women: psychosocial predictors from a 20-year follow-up of women in the Framingham Study. Am J Epidemiol 135:854–864PubMedGoogle Scholar
  56. 56.
    Kawachi I, Colditz GA, Ascherio A et al (1994) Prospective study of phobic anxiety and risk of coronary heart disease in men. Circulation 89:1992–1997PubMedGoogle Scholar
  57. 57.
    Kawachi I, Sparrow D, Vokonas PS, Weiss ST (1994) Symptoms of anxiety and risk of coronary heart disease. The Normative Aging Study. Circulation 90:2225–2229PubMedGoogle Scholar
  58. 58.
    Herrmann C, Brand-Driehorst S, Kaminsky B et al (1998) Diagnostic groups and depressed mood as predictors of 22-month mortality in medical inpatients. Psychosom Med 60:570–577PubMedGoogle Scholar
  59. 59.
    Herrmann C, Brand-Driehorst S, Buss U, Ruger U (2000) Effects of anxiety and depression on 5-year mortality in 5, 057 patients referred for exercise testing. J Psychosom Res 48:455–462PubMedGoogle Scholar
  60. 60.
    Welin C, Lappas G, Wilhelmsen L (2000) Independent importance of psychosocial factors for prognosis after myocardial infarction. J Intern Med 247:629–639PubMedGoogle Scholar
  61. 61.
    Bunker SJ, Colquhoun DM, Esler MD et al (2003) “Stress” and coronary heart disease: psychosocial risk factors. Med J Aust 178:272–276PubMedGoogle Scholar
  62. 62.
    Hachamovitch R, Chang JD, Kuntz RE et al (1995) Recurrent reversible cardiogenic shock triggered by emotional distress with no obstructive coronary disease. Am Heart J 129:1026–1028PubMedGoogle Scholar
  63. 63.
    Januzzi JL, Jr Stern TA, Pasternak RC, DeSanctis RW (2000) The influence of anxiety and depression on outcomes of patients with coronary artery disease. Arch Intern Med 160:1913–1921PubMedGoogle Scholar
  64. 64.
    Carney RM, Freedland KE, Stein PK (2000) Anxiety, depression, and heart rate variability. Psychosom Med 62:84–87PubMedGoogle Scholar
  65. 65.
    Lesperance F, Frasure-Smith N (1996) Negative emotions and coronary heart disease: getting to the heart of the matter. Lancet 347:414–415PubMedGoogle Scholar
  66. 66.
    Sheps DS, Sheffield D (2001) Depression, anxiety, and the cardiovascular system: the cardiologist’s perspective. J Clin Psychiat 62(Suppl 8):12–16Google Scholar
  67. 67.
    Middlekauff HR (1997) Mechanisms and implications of autonomic nervous system dysfunction in heart failure. Curr Opin Cardiol 12:265–275PubMedGoogle Scholar
  68. 68.
    Rundqvist B, Elam M, Bergmann-Sverrisdottir Y et al (1997) Increased cardiac adrenergic drive precedes generalized sympathetic activation in human heart failure. Circulation 95:169–175PubMedGoogle Scholar
  69. 69.
    Mann DL (1999) Mechanisms and models in heart failure: a combinatorial approach. Circulation 100:999–1008PubMedGoogle Scholar
  70. 70.
    Fehder WP (1999) Alterations in immune response associated with anxiety in surgical patients. CRNA 10:124–129PubMedGoogle Scholar
  71. 71.
    Sgoutas-Emch SA, Cacioppo JT, Uchino BN et al (1994) The effects of an acute psychological stressor on cardiovascular, endocrine, and cellular immune response: a prospective study of individuals high and low in heart rate reactivity. Psychophysiol 31:264–271Google Scholar
  72. 72.
    Baggett HL, Saab PG, Carver CS (1996) Appraisal, coping, task performance, and cardiovascular responses during the evaluated speaking task. Personal Soc Psychol Bull 22:483–494Google Scholar
  73. 73.
    Madden K, Savard GK (1995) Effects of mental state on heart rate and blood pressure variability in men and women. Clin Physiol 15:557–569PubMedGoogle Scholar
  74. 74.
    Goldberg AD, Becker LC, Bonsall R et al (1996) Ischemic, hemodynamic, and neurohormonal responses to mental and exercise stress: experience from the Psychophysiological Investigations of Myocardial Ischemia Study (PIMI). Circulation 94:2402–2409PubMedGoogle Scholar
  75. 75.
    Kohn LM, Sleet DA, Carson JC, Gray RT (1983) Life changes and urinary norepinephrine in myocardial infarction. J Hum Stress 9:38–45Google Scholar
  76. 76.
    Yeung AC, Vekshtein VI, Krantz DS et al (1991) The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress. N Eng J Med 325:1551–1556Google Scholar
  77. 77.
    Thayer JF, Friedman BH, Borkovec TD (1996) Autonomic characteristics of generalized anxiety disorder and worry. Biol Psychiat 39:255–266PubMedGoogle Scholar
  78. 78.
    Watkins LL, Grossman P, Krishnan R, Sherwood A (1998) Anxiety and vagal control of heart rate. Psychosom Med 60:498–502PubMedGoogle Scholar
  79. 79.
    Watkins LL, Blumenthal JA, Carney RM (2002) Association of anxiety with reduced baroreflex cardiac control in patients after acute myocardial infarction. Am Heart J 143:460–466PubMedGoogle Scholar
  80. 80.
    Manuck SB (1994) Cardiovascular reactivity in cardiovascular disease: “Once more unto the breach”. Int J Behav Med 1:4–31PubMedGoogle Scholar
  81. 81.
    Manuck SB, Olsson G, Hjemdahl P, Rehnqvist N (1992) Does cardiovascular reactivity to mental stress have prognostic value in postinfarction patients? A pilot study. Psychosom Med 54:102–108PubMedGoogle Scholar
  82. 82.
    Kamarck T, Jennings JR (1991) Biobehavioral factors in sudden cardiac death. Psychol Bull 109:42–75PubMedGoogle Scholar
  83. 83.
    Kop WJ (1999) Chronic and acute psychological risk factors for clinical manifestations of coronary artery disease. Psychosom Med 61:476–487PubMedGoogle Scholar
  84. 84.
    Krantz DS, Kop WJ, Santiago HT, Gottdiener JS (1996) Mental stress as a trigger of myocardial ischemia and infarction. Cardiol Clin 14:271–287PubMedGoogle Scholar
  85. 85.
    Frasure-Smith N, Lesperance F, Talajic M (1995) The impact of negative emotions on prognosis following myocardial infarction: is it more than depression? Health Psychol 14:388–398PubMedGoogle Scholar
  86. 86.
    Hjemdahl P, Larsson PT, Wallen NH (1991) Effects of stress and beta-blockade on platelet function. Circulation 84(6 Suppl):VI-44–VI-61Google Scholar
  87. 87.
    Markovitz JH, Matthews KA (1991) Platelets and coronary heart disease: potential psychophysiologic mechanisms. Psychosom Med 53:643–668PubMedGoogle Scholar
  88. 88.
    von Kanel R, Mills PJ, Fainman C, Dimsdale JE (2001) Effects of psychological stress and psychiatric disorders on blood coagulation and fibrinolysis: a biobehavioral pathway to coronary artery disease? Psychosom Med 63:531–544Google Scholar
  89. 89.
    Patterson SM, Krantz DS, Gottdiener JS et al (1995) Prothrombotic effects of environmental stress: changes in platelet function, hematocrit, and total plasma protein. Psychosom Med 57:592–599PubMedGoogle Scholar
  90. 90.
    Jern C, Eriksson E, Tengborn L et al (1989) Changes of plasma coagulation and fibrinolysis in response to mental stress. Thromb Haemo 62:767–771Google Scholar
  91. 91.
    Grignani G, Soffiantino F, Zucchella M et al (1991) Platelet activation by emotional stress in patients with coronary artery disease. Circulation 83(4 Suppl):II-128–II-136Google Scholar
  92. 92.
    Wallen NH, Held C, Rehnqvist N, Hjemdahl P (1997) Effects of mental and physical stress on platelet function in patients with stable angina pectoris and healthy controls. Eur Heart J 18:807–815PubMedGoogle Scholar
  93. 93.
    Ghiadoni L, Donald AE, Cropley M et al (2000) Mental stress induces transient endothelial dysfunction in humans. Circulation 102:2473–2478PubMedGoogle Scholar
  94. 94.
    Lown B, Verrier RL (1976) Neural activity and ventricular fibrillation. N Eng J Med 294:1165–1170CrossRefGoogle Scholar
  95. 95.
    Lown B, Verrier RL, Rabinowitz SH (1977) Neural and psychologic mechanisms and the problem of sudden cardiac death. Am J Cardiol 39:890–902PubMedGoogle Scholar
  96. 96.
    Middlekauff HR, Mark AL (1998) The treatment of heart failure: the role of neurohumoral activation. Int Med 37:112–122Google Scholar
  97. 97.
    Brodsky MA, Sato DA, Iseri LT et al (1987) Ventricular tachyarrhythmia associated with psychological stress: the role of the sympathetic nervous system. JAMA 257:2064–2067PubMedGoogle Scholar
  98. 98.
    Lown B (1987) Sudden cardiac death:biobehavioral perspective. Circulation 76:I-186–I-196Google Scholar
  99. 99.
    Nadeau RA, de Champlain J (1979) Plasma catecholamines in acute myocardial infarction. Am Heart J 98:548–554PubMedGoogle Scholar
  100. 100.
    Katz C, Martin RD, Landa B, Chadda KD (1985) Relationship of psychologic factors to frequent symptomatic ventricular arrhythmia. Am J Med 78:589–594PubMedGoogle Scholar
  101. 101.
    Fava M, Abraham M, Pava J et al (1996) Cardiovascular risk factors in depression: the role of anxiety and anger. Psychosom 37:31–37Google Scholar
  102. 102.
    Lown B, DeSilva RA, Reich P, Murawski BJ (1980) Psychophysiologic factors in sudden cardiac death. Am J Psychiat 137:1325–1335PubMedGoogle Scholar
  103. 103.
    Tavazzi L, Zotti AM, Rondanelli R (1986) The role of psychologic stress in the gen esis of lethal arrhythmias in patients with coronary artery disease. Eur Heart J 7(Suppl A):99–106PubMedGoogle Scholar
  104. 104.
    Cordero DL, Cagin NA, Natelson BH (1995) Neurocardiology update: role of the nervous system in coronary vasomotion. Cardiovasc Res 29:319–328PubMedGoogle Scholar
  105. 105.
    Rozanski A, Krantz DS, Bairey CN (1991) Ventricular responses to mental stress testing in patients with coronary artery disease: pathophysiological implications. Circulation 83(Suppl 4):II-137–144Google Scholar
  106. 106.
    Kop WJ, Krantz DS, Howell RH et al (2001) Effects of mental stress on coronary epicardial vasomotion and flow velocity in coronary artery disease: relationship with hemodynamic stress responses. J Am Coll Cardiol 37:1359–1366PubMedGoogle Scholar
  107. 107.
    Lacy CR, Contrada RJ, Robbins ML et al (1995) Coronary vasoconstriction induced by mental stress (simulated public speaking) Am J Cardiol 75:503–505PubMedGoogle Scholar
  108. 108.
    LaVeau PJ, Rozanski A, Krantz DS et al (1989) Transient left ventricular dysfunction during provocative mental stress in patients with coronary artery disease. Am Heart J 118:1–8PubMedGoogle Scholar
  109. 109.
    Mazzuero G, Guagliumi G, Bosimini E et al (1989) Effects of psychophysiological activation on coronary flow, cardiac electrophysiology and central hemodynamics in patients with ischemic heart disease. Biblio Cardiol 47–58Google Scholar
  110. 110.
    Okano Y, Utsunomiya T, Yano K (1998) Effect of mental stress on hemodynamics and left ventricular diastolic function in patients with ischemic heart disease. Jap Circ J 62:173–177PubMedGoogle Scholar
  111. 111.
    Jain D, Shaker SM, Burg M et al (1998) Effects of mental stress on left ventricular and peripheral vascular performance in patients with coronary artery disease. J Am Coll Cardiol 31:1314–1322PubMedGoogle Scholar
  112. 112.
    Rozanski A, Blumenthal JA, Kaplan J (1999) Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation 99:2192–2217PubMedGoogle Scholar
  113. 113.
    Mittleman MA, Maclure M, Sherwood JB et al (1995) Triggering of acute myocardial infarction onset by episodes of anger. Circulation 92:1720–1725PubMedGoogle Scholar
  114. 114.
    L’Abbate A, Simonetti I, Carpeggiani C, Michelassi C (1991) Coronary dynamics and mental arithmetic stress in humans. Circulation 83(4 Suppl):II-94–II-99Google Scholar
  115. 115.
    Papademetriou V, Gottdiener JS, Kop WJ et al (1996) Transient coronary occlusion with mental stress. Am Heart J 132:1299–1301PubMedGoogle Scholar
  116. 116.
    Gelernt MD, Hochman JS (1992) Acute myocardial infarction triggered by emotional stress. Am J Cardiol 69:1512–1513PubMedGoogle Scholar
  117. 117.
    Marmot MG (1986) Does stress cause heart attacks? Postgrad Med J 62:683–686PubMedGoogle Scholar
  118. 118.
    Wielgosz AT, Nolan RP (2000) Biobehavioral factors in the context of ischemic cardiovascular diseases. J Psychosom Res 48:339–345PubMedGoogle Scholar
  119. 119.
    Kubzansky LD, Kawachi I, Weiss ST, Sparrow D (1998) Anxiety and coronary heart disease: a synthesis of epidemiological, psychological, and experimental evidence. Ann Behav Med 20:47–58PubMedGoogle Scholar
  120. 120.
    Dakak N, Quyyumi AA, Eisenhofer G et al (1995) Sympathetically mediated effects of mental stress on the cardiac microcirculation of patients with coronary artery disease. American Journal of Cardiology 76:125–130PubMedGoogle Scholar
  121. 121.
    Legault SE, Freeman MR, Langer A, Armstrong PW (1995) Pathophysiology and time course of silent myocardial ischaemia during mental stress: clinical, anatomical, and physiological correlates. British Heart Journal 73:242–249PubMedGoogle Scholar
  122. 122.
    Vita JA, Treasure CB, Yeung AC et al (1992) Patients with evidence of coronary endothelial dysfunction as assessed by acetylcholine infusion demonstrate marked increase in sensitivity to constrictor effects of catecholamines. Circulation 85:1390–1397PubMedGoogle Scholar
  123. 123.
    Arrighi JA, Burg M, Cohen IS et al (2000) Myocardial blood-flow response during mental stress in patients with coronary artery disease. Lancet 356:310–311PubMedGoogle Scholar
  124. 124.
    Freeman LJ, Nixon PG, Sallabank P, Reaveley D (1987) Psychological stress and silent myocardial ischemia. American Heart Journal 114:477–482PubMedGoogle Scholar
  125. 125.
    Rasmussen K, Ravnsbaek J, Funch-Jensen P, Bagger JP (1986) Oesophageal spasm in patients with coronary artery spasm. Lancet 1:174–176PubMedGoogle Scholar
  126. 126.
    Strike PC, Steptoe A (2003) Systematic review of mental stress-induced myocardial ischaemia. European Heart Journal, 24:690–703PubMedGoogle Scholar
  127. 127.
    Rozanski A, Bairey CN, Krantz DS et al (1988a) Mental stress and the induction of silent myocardial ischemia in patients with coronary artery disease. New England Journal of Medicine 318:1005–1012PubMedCrossRefGoogle Scholar
  128. 128.
    Gottdiener JS, Krantz DS, Howell RH et al (1994) Induction of silent myocardial ischemia with mental stress testing: relation to the triggers of ischemia during daily life activities and to ischemic functional severity. Journal of the American College of Cardiology 24:1645–1651PubMedCrossRefGoogle Scholar
  129. 129.
    Mazzuero G, Temporelli PL, Tavazzi L (1991) Influence of mental stress on ventricular pump function in postinfarction patients: an invasive hemodynamic investigation. Circulation 83(4 Suppl):II-145–II-154Google Scholar
  130. 130.
    Bairey CN, Krantz DS, Rozanski A (1990) Mental stress as an acute trigger of ischemic left ventricular dysfunction and blood pressure elevation in coronary artery disease. American Journal of Cardiology 66:28G–31GPubMedGoogle Scholar
  131. 131.
    Burg MM, Jain D, Soufer R et al (1993) Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. Journal of the American College of Cardiology 22:440–448PubMedCrossRefGoogle Scholar
  132. 132.
    Kuroda T, Kuwabara Y, Watanabe S et al (2000) Effect of mental stress on left ventricular ejection fraction and its relationship to the severity of coronary artery disease. European Journal of Nuclear Medicine 27:1760–1767PubMedGoogle Scholar
  133. 133.
    Giannuzzi P, Shabetai R, Imparato A et al (1991) Effects of mental exercise in patients with dilated cardiomyopathy and congestive heart failure: An echocardiographic doppler study. Circulation 83(4 Suppl):II-155–II-165Google Scholar
  134. 134.
    Blumenthal JA, Jiang W, Waugh RA et al (1995) Mental stress-induced ischemia in the laboratory and ambulatory ischemia during daily life: association and hemodynamic features. Circulation 92:2102–2108PubMedGoogle Scholar
  135. 135.
    Buselli EF, Stuart EM (1999) Influence of psychosocial factors and biopsychosocial interventions on outcomes after myocardial infarction. J Cardiovasc Nursing 13:60–72Google Scholar
  136. 136.
    Hayward C (1995) Psychiatric illness and cardiovascular disease risk. Epidemiol Rev 17:129–138PubMedGoogle Scholar
  137. 137.
    Sirois BC, Burg MM (2003) Negative emotion and coronary heart disease. A review. Behav Modif 27:83–102Google Scholar

Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • D. K. Moser
    • 1
  • M. J. De Jong
    • 2
  1. 1.The Journal of Cardiovascular NursingUniversity of Kentucky, College of NursingLexingtonUSA
  2. 2.Support Flight 59th Clinical Research SquadronWilford Hall Medical CenterLackland AFBUSA

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