Depression and CHD: Prevalence, Prognosis, Pathophysiology and Treatment

  • K. Maier
  • D. Chatkoff
  • M. M. Burg


The comorbidity of depression and coronary heart disease (CHD) has been demonstrated in a broad literature published over the past two decades. In this chapter, we review the current state of this literature, with a particular focus on the prevalence of CHD and depression, the relationship of depression to CHD development and prognosis, and the pathophysiological mechanisms by which these two clinical phenomena may be linked. Key issues relevant to clinical practice and research in this area are also discussed, including assessment and treatment.


Depressive Symptom Coronary Heart Disease Heart Rate Variability Acute Coronary Syndrome Patient Beck Depression Inventory Score 


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Copyright information

© Springer-Verlag Italia 2006

Authors and Affiliations

  • K. Maier
    • 1
  • D. Chatkoff
    • 2
  • M. M. Burg
    • 3
    • 4
  1. 1.Psychology DepartmentSalisbury UniversitySalisburyUSA
  2. 2.Department of Behavioral Sciences PsychologyUniversity of Michigan-DearbornDearbornUSA
  3. 3.Behavioral Cardiovascular Health and Hypertension Program Department of MedicineColumbia University School of MedicineNew YorkUSA
  4. 4.Section of Cardiovascular MedicineYale University School of MedicineNew HavenUSA

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