Laryngeal Transplantation

  • Robert R. Lorenz
  • Marshall Strome


Human laryngeal transplantation was first introduced into the literature in the 1960s with experiments using dog models by Boles [1], Ogura et al. [2], and Silver et al [3]. In 1969, Kluyskens and Ringoir attempted to reconstruct the aerodigestive tract after laryngectomy for cancer with a cadaveric transplantation [4]. This transplant was subtotal, preserving recipient perichondrium to revascularize the donor organ without the use of vascular or neural anastomoses. Rapid recurrence of the tumor quashed interest in the procedure for nearly two decades


Donor Organ Recurrent Laryngeal Nerve Vocal Fold Superior Laryngeal Nerve Superior Thyroid Artery 
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Copyright information

© Springer-Verlag Italia 2007

Authors and Affiliations

  • Robert R. Lorenz
    • 1
  • Marshall Strome
    • 2
  1. 1.Section of Head and Neck Surgery, Cleveland Clinic Lerner College of MedicineCase Western Reserve University, The Cleveland Clinic FoundationClevelandUSA
  2. 2.The Head and Neck Institute, Cleveland Clinic Lerner College of MedicineCase Western Reserve University, The Cleveland Clinic FoundationClevelandUSA

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