Analysis of Motor Unit Reinnervation in Muscles of the Transplanted Hand
Sensory and motor recovery in hand-transplanted patients is conditioned by nerve regeneration . Whereas functional recovery can be evaluated clinically , there is a need for tools allowing direct assessment of muscle control in transplanted muscles at the level of their smallest functional units, the motor units (MUs). These should permit, for example, the ability to determine when MUs are innervated and whether their control strategies and physiological properties are similar to those observed in normally innervated muscles. These issues can be assessed by techniques that allow extraction of the electrical activity from single MUs, such as intramuscular electromyography (EMG). However, noninvasive methods detecting EMG signals on the skin (surface EMG) should be preferred in hand-transplanted subjects to minimise possible damage to the allograft.
KeywordsMotor Unit Conduction Velocity Intrinsic Muscle Innervation Zone Instantaneous Firing Rate
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