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Side-Effects and Potential Complications

  • Lionel Badet
  • Palmina Petruzzo
  • Nicole Lefrançois
  • Emmanuel Morelon
  • Xavier Martin
  • Jean-Michel Dubernard

Abstract

Since the first hand transplantation carried out in September 1998, there has been a great deal of discussion concerning the potential risks inducted by the immunosuppressive therapy for the patients transplanted, as they need lifelong immunosuppression. This discussion has been particularly emotional, as composite allograft transplantations (CAT) are not considered as life saving whereas immunosuppressive therapy can expose the recipients to serious side-effects and life-threatening complications. Transplantation is routinely indicated and accepted for non-life-threatening situations, such as dialysis-dependent renal failure and poorly controlled diabetes, because it allows a significant improvement in patient’s quality of life. Consequently, the above rationale might be applied to hand transplantation when functional recovery and improvement in quality of life are demonstrated.

Keywords

Mycophenolate Mofetil Posttransplant Diabetes Posttransplant Malignancy Hand Transplantation Cutaneous Mycosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2007

Authors and Affiliations

  • Lionel Badet
  • Palmina Petruzzo
    • 1
    • 2
  • Nicole Lefrançois
  • Emmanuel Morelon
    • 3
  • Xavier Martin
    • 1
  • Jean-Michel Dubernard
    • 1
  1. 1.Department of TransplantationÉdouard Herriot HospitalLyonFrance
  2. 2.Department of SurgeryUniversity of CagliariItaly
  3. 3.Department of Immunology and Renal Transplantation, Édouard Herriot HospitalClaude Bernard Lyon 1 UniversityLyonFrance

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