Three-Dimensional Spectral Domain Optical Coherence Tomography



Optical coherence tomography (OCT) is an ever evolving technology that has revolutionized ophthalmic imaging. With the advent of spectral domain technology, an unparalleled micrometer axial resolution of 5–10 μm is achieved. With more data acquisition per scanning session, volumetric analysis and three-dimensional imaging are realized (Puliafito et al. 1995; Regatieri et al. 2012; Yannuzzi et al. 2004). Three-dimensional OCT generates OCT fundus images that enable precise registration of OCT images with the image of fundus on standard ophthalmoscopic examination techniques. This allows effortless localization of images for monitoring disease progression and response to therapy. Preservation of retinal topography enables visualization of subtle changes associated with the disease. With rapid evolution in technology, clinical usage of OCT has extended to diseases with more complex morphological features. Improved cellular level resolution has extended the application of spectral domain OCT to retinal degenerations and dystrophies. Three-dimensional imaging, with its increased potential in elucidating retinal morphology, provides a global perspective to various retinal diseases.


Optical Coherence Tomography Retinal Pigment Epithelium Retinal Nerve Fiber Layer Macular Hole Diabetic Macular Edema 
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© Springer India 2017

Authors and Affiliations

  1. 1.Department of OphthalmologyKing George’s Medical UniversityLucknowIndia

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