Complex Scenarios in PDEK



EK may be considered in patients with symptomatic endothelial dysfunction causing oedema, decreased vision and pain. Indications include aphakic and pseudophakic bullous keratopathy, Fuchs’ dystrophy, posterior polymorphous dystrophy, ICE syndrome, endothelial dysfunction secondary to tube cornea touch, failed grafts and so on.


Anterior Chamber Vitreous Cavity Penetrating Keratoplasty Bullous Keratopathy Shallow Anterior Chamber 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Anshu A, Price MO, Price Jr FW. Risk of corneal transplant rejection significantly reduced with Descemet’s membrane endothelial kerato-plasty. Ophthalmology. 2012;119:536–40.CrossRefPubMedGoogle Scholar
  2. 2.
    Weller JM, Tourtas T, Kruse FE. Feasibility and outcome of descemet membrane endothelial keratoplasty in complex anterior segment and vitreous disease. Cornea. 2015;34(11):1351–7.CrossRefPubMedGoogle Scholar
  3. 3.
    Air pump assisted PDEK. Accessed on 8/6/15 at and on 8/6/15 at
  4. 4.
    Williams KA, Roder D, Esterman A, et al. Factors predictive of corneal graft survival. Report from the Australian Corneal Graft Registry. Ophthalmology. 1992;99:403–14.CrossRefPubMedGoogle Scholar
  5. 5.
    Mitry D, Bhogal M, Patel AK, Lee BS, Chai SM, Price MO, Price Jr FW, Jun AS, Aldave AJ, Mehta JS, Busin M, Allan BD. Descemet stripping automated endothelial keratoplasty after failed penetrating keratoplasty: survival, rejection risk, and visual outcome. JAMA Ophthalmol. 2014;132(6):742–9.CrossRefPubMedGoogle Scholar
  6. 6.
    Thompson Jr RW, Price MO, Bowers PJ, Price Jr FW. Long-term graft survival after penetrating keratoplasty. Ophthalmology. 2003;110:1396–402.CrossRefPubMedGoogle Scholar
  7. 7.
    Weisbrod DJ, Sit M, Naor J, Slomovic AR. Outcomes of repeat penetrating keratoplasty and risk factors for graft failure. Cornea. 2003;22:429–34.CrossRefPubMedGoogle Scholar
  8. 8.
    Al-Mezaine H, Wagoner, MD, King Khaled Eye Specialist Hospital Cornea Transplant Study Group. Repeat penetrating keratoplasty: indications, graft survival, and visual outcome. Br J Ophthalmol. 2006;90:324–27.Google Scholar
  9. 9.
    Weller JM, Tourtas T, Kruse FE, Schlötzer-Schrehardt U, Fuchsluger T, Bachmann BO. Descemet membrane endothelial keratoplasty as treatment for graft failure after descemet stripping automated endothelial keratoplasty. Am J Ophthalmol. 2015;159(6):1050–7.e2.CrossRefPubMedGoogle Scholar
  10. 10.
    Ang M, Ho H, Wong C, Htoon HM, Mehta JS, Tan D. Endothelial keratoplasty after failed penetrating keratoplasty: an alternative to repeat penetrating keratoplasty. Am J Ophthalmol. 2014;158(6):1221–7.CrossRefPubMedGoogle Scholar
  11. 11.
    Yoeruek E, Rubino G, Bayyoud T, Bartz-Schmidt KU. Descemet membrane endothelial keratoplasty in vitrectomized eyes: clinical results. Cornea. 2015;34(1):1–5.CrossRefPubMedGoogle Scholar
  12. 12.
    Patel AK, Luccarelli S, Ponzin D, Busin M. Transcorneal suture fixation of posterior lamellar grafts in eyes with minimal or absent iris-lens diaphragm. Am J Ophthalmol. 2011;151(3):460–4.CrossRefPubMedGoogle Scholar
  13. 13.
    Jacob S, Agarwal A, Kumar DA, Agarwal A, Agarwal A, Satish K. Modified technique for combining DMEK with glued intrascleral haptic fixation of a posterior chamber IOL as a single-stage procedure. J Refract Surg. 2014;30(7):492–6.CrossRefPubMedGoogle Scholar
  14. 14.
    Narang P, Agarwal A, Dua HS, Kumar DA, Jacob S, Agarwal A. Glued intrascleral fixation of intraocular lens with pupilloplasty and pre-descemet endothelial keratoplasty: a triple procedure. Cornea. 2015;34(12):1627–31.CrossRefPubMedGoogle Scholar
  15. 15.
    Prakash G, Agarwal A, Jacob S, Kumar DA, Chaudhary P, Agarwal A. Femtosecond-assisted descemet stripping automated endothelial keratoplasty with fibrin glue-assisted sutureless posterior chamber lens implantation. Cornea. 2010;29(11):1315–9.CrossRefPubMedGoogle Scholar
  16. 16.
    Tannan A, Vo RC, Chen JL, Yu F, Deng SX, Aldave AJ. Comparison of ACIOL retention with IOL exchange in patients undergoing descemet stripping automated endothelial keratoplasty. Cornea. 2015;34(9):1030–4.CrossRefPubMedGoogle Scholar
  17. 17.
    Kumar DA, Agarwal A, Prakash G, Jacob S, Saravanan Y, Agarwal A. Glued posterior chamber IOL in eyes with deficient capsular support: a retrospective analysis of 1-year post-operative outcomes. Eye (Lond). 2010;24(7):1143–8.CrossRefGoogle Scholar
  18. 18.
    van Cleynenbreugel H, Remeijer L, Hillenaar T. Cataract surgery in patients with Fuchs’ endothelial corneal dystrophy: when to consider a triple procedure. Ophthalmology. 2014;121(2):445–53.CrossRefPubMedGoogle Scholar
  19. 19.
    Girbardt C, Wiedemann P, Nestler A. Triple descemet membrane endothelial keratoplasty : indications, variations and results. Ophthalmologe. 2016;8.Google Scholar
  20. 20.
    MacLean KD, Apel A, Wilson J, Werner L. Calcification of hydrophilic acrylic intraocular lenses associated with intracameral air injection following DMEK. J Cataract Refract Surg. 2015;41(6):1310–4.CrossRefPubMedGoogle Scholar
  21. 21.
    Maier PC, Heinzelmann S, Böhringer D, Reinhard T. Intraocular lens opacification following posterior lamellar keratoplasty. Klin Monbl Augenheilkd. 2015;232(8):976–81.Open image in new window Open image in new window Open image in new window Open image in new window Open image in new window Open image in new window Open image in new window Google Scholar

Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Dr. Agarwal’s Refractive and Cornea FoundationDr. Agarwal’s Group of Eye HospitalsChennaiIndia

Personalised recommendations