Endothelial Keratoplasty in Eyes with Glaucoma



EK has become the standard of care for corneas with endothelial failure, most commonly Fuchs’, phakic or aphakic bullous keratopathy, failed PK, and the ICE syndromes [1–8]. EK now consists of two main procedures, DSAEK and DMEK (Figs. 3.1 and 3.2). Each procedure replaces the diseased endothelium without surface trephinations, avoiding all the pitfalls of PK. DSAEK donors are comprised of a layer of donor stroma (approximately 125 μm) as a carrier for the donor endothelium while DMEK is pure Descemet’s membrane and endothelium (15 μm). The difference in the donor’s thickness makes the two procedures surgically distinct, but the underlying principles between them are the same. The goal is donor adherence onto the host’s inner surface, thereby creating a new functioning endothelium. This is accomplished with an air bubble (or gas) to tamponade the donor into position.


Large Bubble Slit Lamp Tube Shunt Endothelial Keratoplasty Iris Opening 
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Supplementary material

Video 3.1

(WMV 93323 kb)

Video 3.2

(WMV 15490 kb)


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Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Department of OphthalmologyUniversity of CaliforniaFort MyersUSA

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