Descemet Membrane Endothelial Transfer (DMET)

  • María Satué
  • Fook Chang Lam
  • Isabel Dapena
  • Marieke Bruinsma
  • Gerrit R. J. Melles


Based on recent clinical observations made after DMEK, where the cornea cleared even when an endothelial graft was almost completely detached [1], a new surgical concept was presented at the Netherlands Institute for Innovative Ocular Surgery in 2012: Descemet membrane endothelial transfer (DMET) [2]. Going forward from DMEK, DMET consists of the implantation of a Descemet roll that is mostly “free floating” in the anterior chamber being attached only to the corneal incision [2]. In this chapter, we will discuss the observations that led into the development of DMET and the possible mechanism(s) behind (spontaneous) corneal clearance.


Corneal Endothelial Cell Donor Graft Bullous Keratopathy Endothelial Keratoplasty Descemet Membrane 


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Copyright information

© Springer India 2016

Authors and Affiliations

  • María Satué
    • 1
    • 2
  • Fook Chang Lam
    • 1
    • 2
  • Isabel Dapena
    • 1
    • 2
  • Marieke Bruinsma
    • 1
    • 2
  • Gerrit R. J. Melles
    • 1
    • 2
    • 3
  1. 1.Netherlands Institute for Innovative Ocular SurgeryRotterdamThe Netherlands
  2. 2.Melles Cornea Clinic RotterdamRotterdamThe Netherlands
  3. 3.Amnitrans EyeBank RotterdamRotterdamThe Netherlands

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