Computational Proteomics



Mass Spectrometry (MS) based high throughput proteomics generates huge amount of data, which necessitates the use of computational tools and statistical software for interpreting their biological significance. Herein, we have explored the application of computational proteomics in the bottom-up approach for MS-based protein identification and quantitation. Commonly used scoring systems for interaction proteomics and various tools used in metaproteomic analyses have also been documented. Finally, community standards for proteomics data handling and publicly available proteomics data repositories have been discussed.


Proteomics Data Protein Sequence Database Spectral Count Shotgun Proteomics Human Protein Reference Database 


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Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Centre of Excellence in BioinformaticsBose InstituteKolkataIndia

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