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Nanocarriers of Antifungal Agents

  • Sevgi Güngör
  • M. Sedef Erdal
Chapter

Abstract

Fungal infections are still one of the major healthcare problems worldwide. Particularly, the treatment of invasive fungal infections has become more difficult in high-risk patient groups such as AIDS patients, organ transplant recipients, and cancer patients undergoing immunosuppressive chemotherapy. Superficial fungal infections have a less tendency to develop to systemic infection, but they could be serious due to the inefficiency of the treatment. In addition, the controlling of drug release is also important to minimize systemic absorption and to decrease the toxicity of these agents. Therefore, delivery of antifungal agents used for the treatment of superficial and systemic infections has a great impact in terms of both therapeutic aspect and safety. The novel nano-sized drug carriers play a key role to overcome the limitations of conventional dosage forms to improve the efficacy and to ensure safety of the treatment. In the present chapter, the limitations of conventional drug carriers of fungal agents are concisely emphasized, and the impact of nano-sized carriers in delivering antifungal agents has been addressed, paying particular attention toward the studies performed in recent literature.

Keywords

Fungal Infection Antifungal Agent Invasive Fungal Infection Solid Lipid Nanoparticles Nanostructured Lipid Carrier 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Faculty of Pharmacy, Department of Pharmaceutical TechnologyIstanbul UniversityIstanbulTurkey

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