Management of Sickle Cell Crisis in Pregnancy
Sickle cell disease is a group of inherited single-gene autosomal recessive disorders caused by the ‘sickle’ gene, which affects haemoglobin structure. SCD has its origins in sub-Saharan Africa and the Middle East; hence, it is most prevalent in individuals of African descent as well as in the Caribbean, Middle East, parts of India and the Mediterranean and South and Central America. Owing to population migration, SCD is now of increasing importance worldwide .
KeywordsSickle Cell Anaemia Sickle Cell Sickle Cell Trait Peripartum Cardiomyopathy Acute Chest Syndrome
- 2.Weatherall D, Akinyanju O, Fucharoen S, Olivieri N, Musgrove P, et al. Inherited disorders of haemoglobin. In: Jamison DT, Breman JG, Measham AR, Alleye G, Claeson M, Evans DB, editors. Disease control priorities in developing countries. 2nd ed. Washington, DC/New York: The World Bank/Oxford University Press; 2006. p. 663–80.Google Scholar
- 6.Sickle Cell Society. Standards for the clinical care of adults with sickle cell disease in the UK. London: Sickle Cell Society; 2008.Google Scholar
- 7.Rees DC, Olujohungbe AD, Parker NE, Stephens AD, Telfer P, Wright J, British Committee for Standards in Haematology General Haematology Task Force by the Sickle Cell Working Party. Guidelines for the management of acute painful crisis in sickle cell disease. Br J Haematol. 2003;120:744–52.CrossRefPubMedGoogle Scholar
- 8.National Confidential Enquiry into Patient Outcome and Death. A sickle crisis? A report of the national confidential enquiry into patient outcome and death. London: NCEPOD; 2008.Google Scholar