Microbiology of Ulcer

  • Gopal Nath
  • Gopal Kumar


The primary function of normal, intact skin is to control microbial populations that reside on the skin surface and to prevent underlying tissue from becoming colonized and invaded by potential pathogens. Ulcer causes break in continuity of skin and makes a path for entry of pathogen. Infections of the lower extremity ulcers are a major source of morbidity and important cause of amputation and sometimes mortality in patients particularly with neuropathy and diabetes. Not all ulcers are infected. Evaluation of infection should involve a thorough examination of the extremity for clinical signs of infection along with appropriate laboratory and imaging studies. The organisms implicated are often Staphylococcus aureus (often MRSA in diabetic patients) and Group B streptococci in limb-threatening infection. Chronic infected wounds often have multidrug-resistant pathogens, especially after exposure to health care procedures and use of multiple antibiotics. The presence of a foot ulcer should heighten the index of suspicion for associated infection.


Chronic Wound Fasciitis Necroticans Infected Ulcer Cutaneous Anthrax Resident Flora 
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Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Department of MicrobiologyInstitute of Medical Sciences, Banaras Hindu UniversityVaranasiIndia

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