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Squamous Cell Carcinoma

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Ulcers of the Lower Extremity

Abstract

Cutaneous squamous cell carcinoma (SCC) is a common cancer arising from malignant proliferation of epidermal keratinocytes. SCC represents a broad range of disease, from superficially invasive to aggressive, highly lethal tumors. This chapter will review the epidemiology, risk factors, pathogenesis, diagnosis, and treatment of cutaneous SCC, with a particular focus on disease in the lower extremity.

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Authors and Affiliations

  1. Department of Surgery, University of Washington Seattle, Seattle, WA, USA

    Jonathan G. Sham & Vlad V. Simianu

  2. Department of Pathology, University of Washington/VA Puget Sound, Seattle, WA, USA

    Zhao Ming Dong

  3. Division of Dermatology, Department of Medicine, University of Washington/VA Puget Sound, Seattle, WA, USA

    Nicholas L. Compton

  4. Section of Surgical Oncology, Department of Surgery, University of Washington/VA Puget Sound, Seattle, WA, USA

    Peter C. Wu

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  1. Jonathan G. Sham
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  5. Peter C. Wu
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  1. Banaras Hindu University, Institute of Medical Sciences, Varanasi, India

    Ajay K Khanna

  2. Banaras Hindu University, Institute of Medical Sciences, Varanasi, India

    Satyendra K Tiwary

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Sham, J.G., Simianu, V.V., Dong, Z.M., Compton, N.L., Wu, P.C. (2016). Squamous Cell Carcinoma. In: Khanna, A., Tiwary, S. (eds) Ulcers of the Lower Extremity. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2635-2_22

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