Squamous Cell Carcinoma

  • Jonathan G. Sham
  • Vlad V. Simianu
  • Zhao Ming Dong
  • Nicholas L. Compton
  • Peter C. Wu


Cutaneous squamous cell carcinoma (SCC) is a common cancer arising from malignant proliferation of epidermal keratinocytes. SCC represents a broad range of disease, from superficially invasive to aggressive, highly lethal tumors. This chapter will review the epidemiology, risk factors, pathogenesis, diagnosis, and treatment of cutaneous SCC, with a particular focus on disease in the lower extremity.


Sentinel Lymph Node Basal Cell Carcinoma National Comprehensive Cancer Network Actinic Keratosis Cutaneous Squamous Cell Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer India 2016

Authors and Affiliations

  • Jonathan G. Sham
    • 1
  • Vlad V. Simianu
    • 1
  • Zhao Ming Dong
    • 2
  • Nicholas L. Compton
    • 3
  • Peter C. Wu
    • 4
  1. 1.Department of SurgeryUniversity of Washington SeattleSeattleUSA
  2. 2.Department of PathologyUniversity of Washington/VA Puget SoundSeattleUSA
  3. 3.Division of Dermatology, Department of MedicineUniversity of Washington/VA Puget SoundSeattleUSA
  4. 4.Section of Surgical Oncology, Department of SurgeryUniversity of Washington/VA Puget SoundSeattleUSA

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