Abstract
All particle therapy systems are modular systems built with smaller subsystems. The various modules are (1) the beam production system, (2) the beam transport system, and (3) the beam delivery system as shown in Fig. 2.1.
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Bibliography
Livingston MS, Lawrence EO. The production of high speed light ions without the use of high voltages. Phys Rev. 1932;40:19–35.
Veksler V. Concerning some new methods of acceleration of relativistic particles. Phys Rev. 1945;9:153.
McMillan EM. The synchrotron – a proposed high energy particle accelerator. Phys Rev. 1945;68:143.
Umezawa M. Indianapolis. HITACHI proton beam therapy system. 2013. Particle Beam Therapy Symposium, 55th AAPM Annual Meeting, Indianapolis, Indiana.
Thomas LH. The paths of ions in the cyclotron. Phys Rev. 1938;54:580.
Heyn FA, Tat KK. Operation of a radial sector fixed frequency proton cyclotron. Rev Sci Instrum. 1958;29:662.
Christofilos N. 2736799 USA, 10 Mar 1950.
Courant ED, Livingston MS, Snyder HS. The strong-focusing synchrotron – a new high energy accelerator. Phys Rev. 1952;88:1190–6.
Kerst DW, Terwilliger KM, Jones LW, Symon KR. A fixed field – alternating gradient accelerator with spirally ridged poles MURA-DWK/KMT/LWJ/KRS-3. Midwest Universities Research Assoc. s.l.: Unpublished. 1954.
Dunn PD, Mullett LB, Pickavance TG, Walkinshaw W, Wilkins JJ, editors. Accelerator Studies at A.E.R.E. Harwell, Symposium on high-energy accelerators and pion physics, vol. 1. Geneva: Edouard Regenstreiff; 1956. p. 11–23.
Hiramoto K, Coutrakon G. Synchrotron technology for particle therapy system. 2010. PTCOG 49 Educational Workshop, Chiba, Japan.
Bohm D, Foldy LL. Theory of the synchrocyclotron. Phys Rev. 1947;72:649–61.
Bohm D, Foldy LL. Theory of synchrotron. Phys Rev. 1946;70:249.
Wilson RR. Radiological use of fast protons. Radiology. 1946;47(5):487–91.
Lawrence Radiation Laboratory. LRL Accelerators. Berkeley, California 2010.
McMillan EM. Synchrocyclotron. s.l.: patent US 2615129A. 1947.
The Svedberg Laboratory Historical Notes. [Online] http://www.tsl.uu.se/About_TSL/Historical_notes/.
Published work from Harvard Cyclotron Laboratory. [Online] http://users.physics.harvard.edu/~wilson/cyclotron/cyclotron_publications.html.
Wilson RR. A brief history of the Harvard University Cyclotrons. [Online] 2003. http://users.physics.harvard.edu/~wilson/cyclotron/history.html.
Optivus Proton Therapy Inc. History of Proton Therapy, California 2008.
Mills F, et al. Technical assessment of the Loma Linda University Proton Therapy Accelerator. Batavia: Fermi National Accelerator Laboratory; 1989.
Jongen Y, Laisne A, Lannoye G. France N. Preliminary design of a reduced cost proton therapy facility using a compact, high field isochronous cyclotron. European Particle Accelerator Conference. Nice, France 1990.
Jongen Y. Review on cyclotrons for cancer therapy. Lanzhou: International Conference on Cyclotrons and their Applications. 2010.
Schillo M, et al. Compact superconducting 250 MeV proton cyclotron for the PSI PROSCAN proton therapy project. In: Cyclotrons and their applications. East Lansing: S.n.; 2001.
Antaya T. High-field superconducting synchrocyclotron. PCT/US2007/001628. 19 Jan 2007.
World’s First MEVION S250 Proton Therapy Treatment Delivered at Barnes-Jewish Hospital. [Online] Mevion Medical Systems Inc., 19 Dec 2013. [Cited: 06 27, 2014.] http://www.mevion.com/archived-news/105--worlds-first-mevion-s250-proton-therapy-treatment-delivered-at-barnes-jewish-hospital.
Kleeven W. The IBA superconducting synchrocyclotron project S2C2. Vancouver: Cyclotrons. 2013.
Ion Beam Applications. [Online] http://www.iba-protontherapy.com/proteusone-0.
Kumata Y. Particle Therapy Technologies. 55th AAPM annual meeting, Indianapolis, Indiana 2013. p. 1.
Rocken H. Commissioning and Testing of Varian’s 250 MeV Superconducting ProBeam® Cyclotrons for Proton Therapy. Villigen: European Cyclotron Progress Meeting. 2012.
Tsutsui H, Hashimoto A, Mikami Y, Mitsubori H, Mitsumoto T, Touchi Y, Ueda T, Uno K, Watazawa K, Yajima S, Yoshida J, Yumoto K, Sumitomo Heavy Industries. Design Study of a Superconducting AVF Cyclotron for Proton Therapy. Ltd. Vancouver: Cyclotrons. 2013.
Radovinsky A, Minervini JV, Miller CE, Bromberg L, Michael P, Maggiore M. Superconducting magnets for ultra light and magnetically shielded, compact cyclotrons for medical, scientific, and security applications. IEEE Tran Appl Supercond. 2014;24:3.
Radovinsky AL, Minervini JV, Michael PC, Bromberg L. Variable energy acceleration in a single iron-free. http://www.psfc.mit.edu/library1/catalog/reports/2010/13rr/13rr009/13rr009_full.pdf. [Online] September 2013.
Mevion Medical Systems. [Online] www.mevion.com.
Ueda H. Conceptual design of next generation HTS cyclotron. Osaka: IEEE Trans Appl Supercond. 2013;23:13.
Jongen Y. Cyclotrons from protons to Carbon for Hadron Therapy. Pasadena: PAC; 2013.
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Pearson, E. et al. (2016). Development of Cyclotrons for Proton and Particle Therapy. In: Rath, A., Sahoo, N. (eds) Particle Radiotherapy. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2622-2_3
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