Abstract
Absorbed dose is considered to be the most fundamental physical quantity in describing biological effects of ionizing radiations. The effect is then expressed as a function of the dose, which enables these effects to analyze quantitatively.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Elsässer T, Scholz M. Cluster Effects within the Local Effect Model. Radiat Res. 2007;167:319–29.
Friedrich T, et al. Calculation of the biological effects of ion beams based on the microscopic spatial damage distribution pattern. Int J Radiat Biol. 2012;88:103–7.
Fossati P, et al. Dose prescription in carbon ion radiotherapy: a planning study to compare NIRS and LEM approaches with a clinically-oriented strategy. Phys Med Biol. 2012;57:7543–54.
Hawkins RB. A statistical theory of cell killing by radiation of varying linear energy transfer. Radiat Res. 1994;140:366–74.
Inaniwa T, et al. Treatment planning for a scanned carbon beam with a modified microdosimetric kinetic model. Phys Med Biol. 2010;55(2010):6721–37.
Kanai T, et al. Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy. Int J Radiat Oncol Biol Phys. 1999;44:201–10.
Kanai T, et al. Examination of GyE system for HIMAC carbon therapy. Int J Radiat Oncol Biol Phys. 2006;64:650–6.
Kase Y, et al. Microdosimetric measurements and estimation of human cell survival for heavy-ion beams. Radiat Res. 2006;166:629–38.
Kase Y, et al. Biophysical calculation of cell survival probabilities using amorphous track structure models for heavy-ion irradiation. Phys Med Biol. 2008;53:37–59.
Kellerer M, Rossi HH. A generalized formation of dual radiation action. Radiat Res. 1978;75:471–88.
Krämer M, Scholz M. Treatment planning for heavy-ion radiotherapy: calculation and optimization of biologically effective dose. Phys Med Biol. 2000;45:3319–30.
Matsufuji N, et al. 2007 Specification of carbon ion dose at the National Institute of Radiological Sciences (NIRS). J Radiat Res. 2007;48:81–6.
Miyamoto T, et al. Carbon ion radiotherapy for stage I non-small cell lung cancer. Radiother Oncol. 2003;66:127–40.
Scholz M, Elsässer T. Biophysical models in ion beam radiotherapy. Adv Space Res. 2007;40:1381–91.
Scholz M, Kraft G. Track structure and the calculation of biological effects of heavy charged particles. Adv Space Res. 1996;18:5–14.
Weyrather W, et al. RBE for carbon track-segment irradiation in cell lines of differing repair capacity. Int J of Radiation Biol. 1999;75:1357–64.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer India
About this chapter
Cite this chapter
Matsufuji, N. (2016). Modeling of Biological Effect of Charged Particles for C-Ion RT. In: Rath, A., Sahoo, N. (eds) Particle Radiotherapy. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2622-2_11
Download citation
DOI: https://doi.org/10.1007/978-81-322-2622-2_11
Publisher Name: Springer, New Delhi
Print ISBN: 978-81-322-2621-5
Online ISBN: 978-81-322-2622-2
eBook Packages: MedicineMedicine (R0)