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Moving Forward: Expected Opportunities for the Development of New Therapeutic Agents Based on Nanotechnologies

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Abstract

This chapter provides a detailed overview of the explosive, exponential growth in the use of nanomaterials as carriers for therapeutic radioisotopes using a variety of new unique concepts for radioisotope attachment and targeted delivery. These very small targeting agents for the applications discussed in this chapter are essentially platforms to which therapeutic radioisotopes can be stably attached for transport to the target sites, which are generally tumor cells. Because of their very small size—i.e., at least 100 nm in one dimension—they must be small enough for transit through the small capillaries. As discussed in this chapter, these nanocarriers can be composed of a large variety of materials to which specific targeting moieties and radioisotopes can be attached by many different strategies.

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  1. Nuclear Security and Isotope Division, Oak Ridge National Laboratory, OAK RIDGE, USA

    F. F. (Russ) Knapp

  2. Isotope Production and Applications Division, Bhabha Atomic Research Centre, Mumbai, India

    Ashutosh Dash

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Knapp, F.F.(., Dash, A. (2016). Moving Forward: Expected Opportunities for the Development of New Therapeutic Agents Based on Nanotechnologies. In: Radiopharmaceuticals for Therapy . Springer, New Delhi. https://doi.org/10.1007/978-81-322-2607-9_16

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