Skull Base Surgery in the Twenty-First Century

  • Ziv Gil
  • Dan M. Fliss
Part of the Head and Neck Cancer Clinics book series (HNCC)


Skull base tumours (SBTs) include a variety of neoplasms that originate in the paranasal sinuses, skull base, meninges or brain. These tumours can be of bone or soft tissue origin. The incidence of these tumours varies according to demographical and geographical factors, as well as exposure to different carcinogens. Tumours originating at different sites also differ in their pathophysiology, biological behaviour, and sensitivity to radiotherapy (RT) and chemotherapy. All these factors play an important role in tailoring treatment in this population. Standardization of staging paradigms has allowed uniformity in categorizing tumour status and histology, enabling common guidelines to be established for evaluating and treating skull base cancers.


Skull Base Paranasal Sinus Anterior Skull Base Skull Base Surgery Skull Base Tumour 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© The Author(s)  2012

Authors and Affiliations

  1. 1.Head and Neck Surgery Unit, Department of Otolaryngology, Head and Neck and Maxillofacial SurgeryTel Aviv Sourasky Medical Center, Tel Aviv UniversityTel AvivIsrael
  2. 2.Department of Otolaryngology, Head and Neck and Maxillofacial SurgeryTel Aviv Sourasky Medical Center, Tel Aviv UniversityTel AvivIsrael

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