Abstract
Skull base tumours (SBTs) include a variety of neoplasms that originate in the paranasal sinuses, skull base, meninges or brain. These tumours can be of bone or soft tissue origin. The incidence of these tumours varies according to demographical and geographical factors, as well as exposure to different carcinogens. Tumours originating at different sites also differ in their pathophysiology, biological behaviour, and sensitivity to radiotherapy (RT) and chemotherapy. All these factors play an important role in tailoring treatment in this population. Standardization of staging paradigms has allowed uniformity in categorizing tumour status and histology, enabling common guidelines to be established for evaluating and treating skull base cancers.
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Gil, Z., Fliss, D.M. (2012). Skull Base Surgery in the Twenty-First Century. In: Gil, Z., Fliss, D. (eds) Tumours of the Skull Base and Paranasal Sinuses. Head and Neck Cancer Clinics. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2583-6_1
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DOI: https://doi.org/10.1007/978-81-322-2583-6_1
Publisher Name: Springer, New Delhi
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