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Prospects of Bioactive Chitosan-Based Scaffolds in Tissue Engineering and Regenerative Medicine

  • M. PrabaharanEmail author
  • P. R. Sivashankari
Chapter
Part of the Springer Series on Polymer and Composite Materials book series (SSPCM)

Abstract

Chitosan, a natural-based polymer obtained by alkaline deacetylation of chitin, is non-toxic, biocompatible, and biodegradable. Due to its desired properties, chitosan-based materials are widely considered to fabricate scaffolds for tissue engineering and regenerative medicine. These scaffolds provide characteristic advantages, such as preservation of cellular phenotype, binding and enhancement of bioactive factors, control of gene expression, and synthesis and deposition of tissue-specific extracellular matrix (ECM), to tissue regeneration. Therefore, the scaffolds based on chitosan and its composites have potential to be used in bone, cartilage, liver, nerve, and musculoskeletal tissue engineering.

Keywords

Chitosan Scaffolds Tissue engineering Bioactivity Regenerative medicine 

Notes

Acknowledgments

The authors thank DST-Nano Mission, Department of Science and Technology, Government of India for their financial support.

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Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Department of ChemistryHindustan Institute of Technology and ScienceChennaiIndia

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