Merkel Cell Carcinoma, Adnexal Carcinoma and Basal Cell Carcinoma

  • Michael Veness
  • Julie Howle
Part of the Head and Neck Cancer Clinics book series (HNCC)


Merkel cell carcinomas (MCCs) are derived from the mechanoreceptor cells located in the basal layer of the epidermis and are considered a primary cutaneous neuroendocrine malignancy with characteristically small, round blue cells seen on microscopy [1]. MCC is uncommon, but the incidence is rising and markedly increased in immunosuppressed patients. Chronic sun exposure is presumed to be the chief aetiological factor but, more recently, emerging evidence suggests that merkel cell polyomavirus may also contribute to its development [2]. MCC is considered an aggressive skin malignancy in most patients, with a propensity to locoregional and distant relapse.


Adenoid Cystic Carcinoma Merkel Cell Carcinoma Sebaceous Carcinoma Mohs Micrographic Surgery Apocrine Carcinoma 
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Copyright information

© Faruque Riffat, Carsten E. Palme, Michael Veness, Rehan Kazi, Raghav C. Dwivedi 2015

Authors and Affiliations

  1. 1.Radiation Oncology, Westmead HospitalWestmead University of SydneySydneyAustralia
  2. 2.Department of Surgical Oncology, Westmead Cancer Care Centre, Westmead Hospital, WestmeadUniversity of SydneySydneyAustralia

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