Abstract
From the early 1930s, Frederic E. Mohs developed the idea of cancer excision with microscopic assistance, a concept which has become known as Mohs micrographic surgery [1]. Initially, a fixed tissue technique was employed using zinc chloride solution; however, today most practitioners employ a fresh-tissue approach [2]. Mohs surgery is a microscopically controlled procedure that allows maximal excision of involved tumour in cutaneous neoplasms while minimizing the excision of uninvolved tissue. It achieves this through mapping the surgical site and successive resection of tumour and subsequent histological analysis of resected borders until clear margins are achieved [3]. Mohs surgery is suited to cutaneous neoplasms in areas with high risk of local recurrence or where for functional or cosmetic reasons tissue is required to be preserved, or in recurrent neoplasms, in particular, large and aggressive tumours with irregular or incomplete resection borders [1].
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© 2015 Faruque Riffat, Carsten E. Palme, Michael Veness, Rehan Kazi, Raghav C. Dwivedi
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Robinson, D., Roth, J. (2015). Mohs Surgery and Facial Flaps. In: Riffat, F., Palme, C., Veness, M. (eds) Non-melanoma Skin Cancer of the Head and Neck. Head and Neck Cancer Clinics. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2497-6_5
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DOI: https://doi.org/10.1007/978-81-322-2497-6_5
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