Brittle Bones and Frequent Fractures
Frequent fractures following trivial trauma or during normal daily activities occur in a group of conditions where the bones are brittle. The most common of these conditions is osteogenesis imperfecta (Plotkin 2004). Various types of osteogenesis imperfecta have been described; the severity, the frequency of fractures, and other clinical features vary in each of the types (Sillence et al. 1979; Sillence 1988; Glorieux et al. 2000).