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Functional Genomics: Applications in Plant Science

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Abstract

The completion of the Arabidopsis Genome Initiative project in the year 2000 and decoding the whole genome sequence of many plant species thereafter lead to generation of mountains of sequence information. But the function of most of these sequences remains elusive. This grand challenge of defining the function of all the sequence information and genes has been the scope of functional genomics. Functional genomics deals with the function of gene at transcription, at translation and at regulation level. Numerous techniques including microarray, serial analysis of gene expression (SAGE), gene knockout, RNA interference (RNAi), virus-induced gene silencing (VIGS), insertional mutagenesis, Targeting Induced Local Lesions in Genomes (TILLING), EcoTILLING and next-generation sequencing (NGS) technologies have been developed as component of functional genomics to elucidate the function of genes/sequences and can assist in understanding the genetic mechanism of growth, development and physiological responses of plant. Therefore, functional genomics can aid in discovery of alleles/QTLs, development of high-throughput markers, development of high-density linkage map and ultimately assigning the function of genes/QTLs related with yield and associated traits and biotic and abiotic stress tolerance to develop high yielding genotypes to mitigate the challenges of global food security.

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Correspondence to Uday Chand Jha Ph.D. .

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Jha, U.C., Bhat, J.S., Patil, B.S., Hossain, F., Barh, D. (2015). Functional Genomics: Applications in Plant Science. In: Barh, D., Khan, M., Davies, E. (eds) PlantOmics: The Omics of Plant Science. Springer, New Delhi. https://doi.org/10.1007/978-81-322-2172-2_4

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