Applications of PET in Management of Brain Tumors
Brain tumors being structural lesions of the brain and their diagnosis and management are primarily dependent on computed tomography (CT) and magnetic resonance imaging (MRI), the latter being the standard method for evaluating both primary and metastatic tumors of the brain with excellent sensitivity. Positron emission tomography (PET) provides physiological information related to tumor metabolism, proliferation rate, aggressiveness, and invasiveness. It indirectly also provides information on the functional interaction of the tumor with the remaining brain. In fact, the first oncological application of PET was for the assessment of brain tumors. The state-of-the-art PET scanners available today provide excellent anato-metabolically coregistered images with the added utility of CT for attenuation correction of PET images. The future of fusion technology, which has recently been launched in global markets, is the integrated PET/MRI scanner, and the one important area which definitely stands to benefit from this technology is the brain.
KeywordsPositron Emission Tomography Brain Metastasis Primary Central Nervous System Lymphoma Radiation Necrosis Leptomeningeal Metastasis
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